AutismKB 2.0

Annotation Detail for THBS2


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Basic Information Top
Gene Symbol:THBS2 ( TSP2 )
Gene Full Name: thrombospondin 2
Band: 6q27
Quick LinksEntrez ID:7058; OMIM: 188061; Uniprot ID:TSP2_HUMAN; ENSEMBL ID: ENSG00000186340; HGNC ID: 11786
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
151N-linked (GlcNAc...) (Potential).
316N-linked (GlcNAc...) (Potential).
330N-linked (GlcNAc...) (Potential).
457N-linked (GlcNAc...) (Potential).
584N-linked (GlcNAc...).
710N-linked (GlcNAc...).
930Cell attachment site (Potential).
1069N-linked (GlcNAc...).
Location(AA) Modifications Resource
151N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
316N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
330N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
457N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
584N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
710N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1069N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
109Phosphoserine(ATM)HMM predict
151N-linkedHMM predict
180SulfotyrosineHMM predict
316N-linkedHMM predict
330N-linkedHMM predict
337O-linkedHMM predict
362Phosphoserine(CDC2)HMM predict
362O-linkedHMM predict
384C-linkedHMM predict
387C-linkedHMM predict
390C-linkedHMM predict
394O-linkedHMM predict
407Phosphoserine(PKB)HMM predict
422Phosphothreonine(PKC)HMM predict
440C-linkedHMM predict
443C-linkedHMM predict
446C-linkedHMM predict
457N-linkedHMM predict
466Phosphoserine(CDC2)HMM predict
466Phosphoserine(CDK)HMM predict
497C-linkedHMM predict
500C-linkedHMM predict
503C-linkedHMM predict
509O-linkedHMM predict
518Phosphothreonine(PKA)HMM predict
523Phosphoserine(IKK)HMM predict
523Phosphoserine(CDC2)HMM predict
523Phosphoserine(CDK)HMM predict
566Phosphoserine(IKK)HMM predict
577S-palmitoylHMM predict
584N-linkedHMM predict
641Phosphothreonine(PKC)HMM predict
710N-linkedHMM predict
781Phosphotyrosine(Jak)HMM predict
800Phosphoserine(ATM)HMM predict
878Phosphotyrosine(Jak)HMM predict
1024Phosphotyrosine(EGFR)HMM predict
1024SulfotyrosineHMM predict
1069N-linkedHMM predict
1088Phosphothreonine(MAPK)HMM predict
1122Phosphotyrosine(Jak)HMM predict
1141Phosphotyrosine(INSR)HMM predict
1141SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003247
  • Location:chr6 169357800-169396061
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 169401846 169402443 597 6083
CTCF G2GSE9613 169404754 169406180 1426 9406
CTCF G2GSE9613 169407730 169408163 433 11885
USF2 HepG2E 169402214 169402987 773 6539
hScc1 BcellGSE12603 169401956 169402297 341 6065
hScc1 BcellGSE12603 169404729 169405466 737 9036
p63 keratinocytesGSE17611 169396360 169397641 1281 939
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 169339137 169339318 181 18573
CTCF G2GSE9613 169355032 169355841 809 2364
Oct4 hESGSE17917 169355043 169355294 251 2632
P300 T30-glioblastomaGSE21026 169356662 169357481 819 729
c MYCMCF7 169339137 169339318 181 18573
hScc1 BcellGSE12603 169339137 169339318 181 18573
hScc1 BcellGSE12603 169339754 169340054 300 17897
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 169364314 169364486 172 0
CTCF G2GSE9613 169367377 169367597 220 0
CTCF G2GSE9613 169368845 169369162 317 0
CTCF G2GSE9613 169373517 169373806 289 0
CTCF G2GSE9613 169374061 169376293 2232 0
CTCF G2GSE9613 169378936 169379182 246 0
CTCF G2GSE9613 169379615 169379995 380 0
CTCF G2GSE9613 169383941 169384468 527 0
ER MCF7GSE19013 169367180 169367691 511 0
Oct4 hESGSE21916 169394441 169395187 746 0
TAF k562GSE8489 169375509 169376293 784 0
hScc1 BcellGSE12603 169373517 169373875 358 0
hScc1 BcellGSE12603 169374349 169375651 1302 0
hScc1 BcellGSE12603 169376661 169376911 250 0
hScc1 BcellGSE12603 169390227 169390550 323 0
hScc1 G2GSE9613 169374274 169375615 1341 0
p63 keratinocytesGSE17611 169365657 169366802 1145 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23495 EST chr6 169431126 169457288 23781 mRNA THBS2 chr6 169433507 169471769 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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