AutismKB 2.0

Annotation Detail for THBS3


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Basic Information Top
Gene Symbol:THBS3 ( MGC119564,MGC119565,TSP3 )
Gene Full Name: thrombospondin 3
Band: 1q22
Quick LinksEntrez ID:7059; OMIM: 188062; Uniprot ID:TSP3_HUMAN; ENSEMBL ID: ENSG00000169231; HGNC ID: 11787
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
228Phosphothreonine.
310N-linked (GlcNAc...) (Potential).
407N-linked (GlcNAc...) (Potential).
644N-linked (GlcNAc...) (Potential).
937N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
310N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
407N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
644N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
937N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
310N-linkedHMM predict
349O-linkedHMM predict
397S-palmitoylHMM predict
400S-palmitoylHMM predict
420Phosphoserine(IKK)HMM predict
420Phosphoserine(CDK)HMM predict
420Phosphoserine(CDC2)HMM predict
420O-linkedHMM predict
464SulfotyrosineHMM predict
530Phosphoserine(CK2)HMM predict
587Phosphothreonine(PKC)HMM predict
600Phosphoserine(IKK)HMM predict
606N-linkedHMM predict
644N-linkedHMM predict
646Phosphoserine(ATM)HMM predict
671Phosphotyrosine(INSR)HMM predict
791Phosphotyrosine(Syk)HMM predict
791SulfotyrosineHMM predict
816Phosphotyrosine(SRC)HMM predict
937N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007112
  • Location:chr1 153432004-153444313
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 153443288 153445757 2469 209
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 153430928 153431293 365 894
Rb QuiescentGSE19898 153431159 153431641 482 605
Rb SenescentGSE19898 153431096 153431939 843 487
TAF k562GSE8489 153430746 153431062 316 1101
p130 QuiescentGSE19898 153431237 153431467 230 653
p130 shRbSenescentGSE19898 153431141 153431500 359 684
p130 shRbSenescentGSE19898 153431717 153432023 306 135
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 153443280 153443606 326 0
CTCF CD4SISSRdata 153443280 153443606 326 0
CTCF G2GSE9613 153433599 153433780 181 0
CTCF G2GSE9613 153437868 153438361 493 0
CTCF G2GSE9613 153442520 153442905 385 0
H3ac HepG2E 153443733 153444058 325 0
Oct1 HelaGSE14283 153435599 153435655 56 0
TAF k562GSE8489 153443288 153443474 186 0
hScc1 BcellGSE12603 153443288 153443987 699 0
hScc1 CdLSGSE12603 153443288 153443733 445 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018