AutismKB 2.0

Annotation Detail for TIAL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TIAL1 ( MGC33401,TCBP,TIAR )
Gene Full Name: TIA1 cytotoxic granule-associated RNA binding protein-like 1
Band: 10q26.11
Quick LinksEntrez ID:7073; OMIM: 603413; Uniprot ID:TIAR_HUMAN; ENSEMBL ID: ENSG00000151923; HGNC ID: 11804
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
50Phosphotyrosine.
122N6-acetyllysine.
201Phosphoserine.
Location(AA) Modifications Resource
50Phosphotyrosine.Swiss-Prot 53.0
Location(AA) Modification Resource
85Phosphothreonine(CDC2)HMM predict
85Phosphothreonine(CDK)HMM predict
87Phosphoserine(CDK)HMM predict
87Phosphoserine(CDC2)HMM predict
88Phosphoserine(ATM)HMM predict
109Phosphothreonine(CK2)HMM predict
186N-linkedHMM predict
187N-linkedHMM predict
198N-linkedHMM predict
204N-linkedHMM predict
226Phosphoserine(CDK)HMM predict
226Phosphoserine(CDC2)HMM predict
242Phosphotyrosine(SRC)HMM predict
261N-linkedHMM predict
293C-linkedHMM predict
296C-linkedHMM predict
306Phosphotyrosine(Abl)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001033925
  • Location:chr10 121322969-121346530
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 121357889 121358084 195 11456
CTCF CD4SISSRdata 121357889 121358084 195 11456
CTCF HelaGSE12889 121357882 121358190 308 11506
E2F4 G0GSE7516 121346422 121347886 1464 624
LIN9 G0GSE7516 121346349 121347614 1265 451
LIN9 SGSE7516 121346218 121347075 857 116
Oct1 HelaGSE14283 121351966 121351995 29 5450
Rb shRbQuiescentGSE19898 121365925 121366055 130 19460
TFAP2C MCF7GSE21234 121346356 121346918 562 107
hScc1 CdLSGSE12603 121357823 121358246 423 11504
hScc1 G2GSE9613 121357823 121358319 496 11541
p130 QuiescentGSE19898 121346320 121346957 637 108
p130 SenescentGSE19898 121346495 121347093 598 264
p130 shRbQuiescentGSE19898 121346222 121347414 1192 288
p130 shRbSenescentGSE19898 121346641 121347173 532 377
p130 G0GSE7516 121346307 121347587 1280 417
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 121313471 121313505 34 9482
Oct1 HelaGSE14283 121307871 121307902 31 15083
Oct1 HelaGSE14283 121313467 121313493 26 9490
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 121345689 121347223 1534 0
H3K4me2 HCT116GSE10453 121344441 121345354 913 0
H3K4me3 colorectalcancer 121344772 121345389 617 0
H3ac HepG2E 121344441 121345767 1326 0
H3ac HepG2E 121346218 121346707 489 0
Oct1 H2O2-HelaGSE14283 121331003 121331034 31 0
Oct1 H2O2-HelaGSE14283 121341552 121341588 36 0
Oct1 HelaGSE14283 121330999 121331039 40 0
Oct1 HelaGSE14283 121341553 121341587 34 0
PHF8 HeLaGSE20725 121345478 121347078 1600 0
PolII HeLaGSE12783 121345147 121347789 2642 0
SRF HelaGSE8489 121324796 121325464 668 0
TAF HelaGSE8489 121324831 121325464 633 0
TAF k562GSE8489 121344441 121345295 854 0
hScc1 BcellGSE12603 121345422 121346648 1226 0
p130 QuiescentGSE19898 121345112 121345527 415 0
p130 QuiescentGSE19898 121346094 121346308 214 0
p130 SenescentGSE19898 121344967 121345508 541 0
p130 shRbSenescentGSE19898 121344791 121345503 712 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7g hsa-let-7g 3 21293479
hsa-let-7g* hsa-let-7g 3 21293479
hsa-miR-125b hsa-mir-125b-1 11 20435889
hsa-miR-125b hsa-mir-125b-2 21 20435889
hsa-miR-126 hsa-mir-126 9 21293479
hsa-miR-126* hsa-mir-126 9 21293479
hsa-miR-196a hsa-mir-196a-1 17 21293479
hsa-miR-196a hsa-mir-196a-2 12 21293479
hsa-miR-221 hsa-mir-221 X 20435889
hsa-miR-221* hsa-mir-221 X 20435889
hsa-miR-31 hsa-mir-31 9 21293479
hsa-miR-31* hsa-mir-31 9 21293479
hsa-miR-338-3p hsa-mir-338 17 21293479
hsa-miR-338-5p hsa-mir-338 17 21293479
hsa-miR-579 hsa-mir-579 5 20435889
hsa-miR-7 hsa-mir-7-1 9 21293479
hsa-miR-7 hsa-mir-7-2 15 21293479
hsa-miR-7 hsa-mir-7-3 19 21293479
hsa-miR-98 hsa-mir-98 X 21293479
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved