AutismKB 2.0

Annotation Detail for TIAM1


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Basic Information Top
Gene Symbol:TIAM1 ( FLJ36302 )
Gene Full Name: T-cell lymphoma invasion and metastasis 1
Band: 21q22.11
Quick LinksEntrez ID:7074; OMIM: 600687; Uniprot ID:TIAM1_HUMAN; ENSEMBL ID: ENSG00000156299; HGNC ID: 11805
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
231Phosphoserine.
356Phosphoserine.
358Phosphoserine.
1323Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
2N-myristoyl glycine (Potential).Swiss-Prot 53.0
231Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
6Phosphoserine(ATM)HMM predict
24N-linkedHMM predict
26Phosphothreonine(PKC)HMM predict
26Phosphothreonine(PKA)HMM predict
39Phosphothreonine(PKA)HMM predict
43PhosphoserineHMM predict
55O-linkedHMM predict
58O-linkedHMM predict
59O-linkedHMM predict
60Phosphoserine(PKB)HMM predict
61O-linkedHMM predict
63Phosphoserine(IKK)HMM predict
63Phosphoserine(CK1)HMM predict
63O-linkedHMM predict
77Phosphoserine(ATM)HMM predict
111Phosphoserine(IKK)HMM predict
114O-linkedHMM predict
115Phosphoserine(IKK)HMM predict
119O-linkedHMM predict
141Phosphotyrosine(Syk)HMM predict
151Phosphoserine(CAMK2)HMM predict
151Phosphoserine(PKB)HMM predict
151PhosphoserineHMM predict
151Phosphoserine(IKK)HMM predict
158O-linkedHMM predict
170Phosphoserine(PKG)HMM predict
184Phosphoserine(CK1)HMM predict
189Phosphoserine(ATM)HMM predict
189Phosphoserine(CK1)HMM predict
194Phosphothreonine(CK2)HMM predict
195Phosphoserine(CK1)HMM predict
219Phosphoserine(CDC2)HMM predict
224Phosphoserine(IKK)HMM predict
280Phosphothreonine(MAPK)HMM predict
283Phosphotyrosine(SRC)HMM predict
286Phosphotyrosine(Syk)HMM predict
319Phosphothreonine(PKC)HMM predict
351N-linkedHMM predict
354N-linkedHMM predict
358O-linkedHMM predict
358O-linkedHMM predict
370O-linkedHMM predict
372Phosphoserine(CK1)HMM predict
373O-linkedHMM predict
394Phosphoserine(CK1)HMM predict
409Phosphoserine(ATM)HMM predict
409Phosphoserine(CK1)HMM predict
413Phosphoserine(CK1)HMM predict
419Phosphoserine(CDC2)HMM predict
433Phosphothreonine(PKC)HMM predict
456Phosphoserine(PKA)HMM predict
531Phosphoserine(IKK)HMM predict
590Phosphoserine(IKK)HMM predict
679Phosphothreonine(PKA)HMM predict
694Phosphoserine(CK1)HMM predict
779Phosphothreonine(PKC)HMM predict
829Phosphotyrosine(EGFR)HMM predict
829Phosphotyrosine(INSR)HMM predict
829Phosphotyrosine(SRC)HMM predict
829Phosphotyrosine(Syk)HMM predict
829SulfotyrosineHMM predict
887MethyllysineHMM predict
890MethyllysineHMM predict
907N-linkedHMM predict
939Phosphoserine(ATM)HMM predict
965Phosphoserine(PKA)HMM predict
972Phosphoserine(IKK)HMM predict
989Phosphoserine(CK2)HMM predict
989Phosphoserine(CK1)HMM predict
995Phosphoserine(IKK)HMM predict
998Phosphoserine(CK1)HMM predict
1013N-linkedHMM predict
1018N-linkedHMM predict
1020O-linkedHMM predict
1020Phosphoserine(CDC2)HMM predict
1087N-linkedHMM predict
1211Phosphoserine(CK1)HMM predict
1321Phosphoserine(CK1)HMM predict
1323SulfotyrosineHMM predict
1376S-palmitoylHMM predict
1377S-palmitoylHMM predict
1379Phosphoserine(CDC2)HMM predict
1407Phosphoserine(IKK)HMM predict
1410Phosphoserine(CK1)HMM predict
1411Phosphoserine(ATM)HMM predict
1414Phosphotyrosine(Syk)HMM predict
1433O-linkedHMM predict
1433O-linkedHMM predict
1437Phosphoserine(PKG)HMM predict
1437Phosphoserine(PKB)HMM predict
1456Phosphothreonine(PKA)HMM predict
1463Phosphoserine(IKK)HMM predict
1466Phosphoserine(CDC2)HMM predict
1493Phosphotyrosine(Syk)HMM predict
1506Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003253
  • Location:chr21 31412606-31853160
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 31852358 31854348 1990 193
p130 QuiescentGSE19898 31853626 31853829 203 567
p130 SenescentGSE19898 31853291 31853497 206 234
p130 shRbSenescentGSE19898 31853316 31853499 183 247
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 31392704 31393153 449 19678
CTCF CD4SISSRdata 31392704 31393153 449 19678
CTCF JurkatGSE12889 31392822 31393044 222 19674
CTCF G2GSE9613 31392556 31393305 749 19676
Oct4 hESGSE17917 31392822 31393173 351 19609
hScc1 BcellGSE12603 31392480 31393385 905 19674
hScc1 CdLSGSE12603 31392378 31393533 1155 19651
hScc1 G2GSE9613 31392590 31393305 715 19659
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T0-glioblastomaGSE21026 31767615 31767854 239 0
CBP T0-glioblastomaGSE21026 31800932 31801445 513 0
CBP T30-glioblastomaGSE21026 31837180 31838078 898 0
CTCF CD4GSE12889 31436865 31437069 204 0
CTCF CD4GSE12889 31508129 31508273 144 0
CTCF CD4GSE12889 31803845 31804048 203 0
CTCF CD4SISSRdata 31436865 31437069 204 0
CTCF CD4SISSRdata 31508129 31508273 144 0
CTCF CD4SISSRdata 31803845 31804048 203 0
CTCF G2GSE9613 31558775 31558904 129 0
CTCF G2GSE9613 31641494 31642035 541 0
CTCF G2GSE9613 31753539 31753994 455 0
CTCF G2GSE9613 31803547 31804189 642 0
ER MCF7GSE19013 31786659 31787120 461 0
ER MCF7GSE19013 31823482 31824029 547 0
FOXA1 MCF7GSE15244 31489169 31489545 376 0
FOXA1 MCF7GSE15244 31572034 31572593 559 0
FOXA1 MCF7GSE15244 31604672 31605443 771 0
FOXA1 MCF7GSE15244 31610827 31611223 396 0
FOXA1 MCF7GSE15244 31628405 31629396 991 0
FOXA1 MCF7GSE15244 31641527 31642035 508 0
FOXA1 MCF7GSE15244 31719329 31719611 282 0
FOXA1 MCF7GSE15244 31799188 31799903 715 0
FOXA1 MCF7GSE15244 31802887 31804189 1302 0
FOXA1 MCF7GSE15244 31823416 31825954 2538 0
FOXA1 MCF7GSE15244 31847959 31848331 372 0
Fos K562GSE19551 31784566 31785001 435 0
Fos K562GSE19551 31803848 31804270 422 0
FoxA1 MCF7MACSdata 31489182 31489358 176 0
FoxA1 MCF7MACSdata 31530419 31530791 372 0
FoxA1 MCF7MACSdata 31823575 31823795 220 0
KLF4 hESGSE17917 31414877 31415157 280 0
KLF4 hESGSE17917 31546169 31546334 165 0
Myc K562GSE19551 31431094 31431328 234 0
Myc K562GSE19551 31576555 31576870 315 0
Myc K562GSE19551 31803736 31804289 553 0
NFkBII GM12878GSE19485 31811759 31812721 962 0
Nanog ESGSE20650 31487955 31488346 391 0
Nanog hESGSE18292 31453324 31453804 480 0
Nanog hESGSE18292 31633281 31633582 301 0
P300 T0-glioblastomaGSE21026 31702301 31703105 804 0
P300 T0-glioblastomaGSE21026 31820188 31820808 620 0
P300 T0-glioblastomaGSE21026 31837418 31838157 739 0
P300 T30-glioblastomaGSE21026 31576086 31576997 911 0
P300 T30-glioblastomaGSE21026 31587948 31588704 756 0
P300 T30-glioblastomaGSE21026 31628703 31629793 1090 0
P300 T30-glioblastomaGSE21026 31660728 31661612 884 0
P300 T30-glioblastomaGSE21026 31820221 31820690 469 0
P300 T30-glioblastomaGSE21026 31837163 31838065 902 0
RARA MCF7GSE15244 31641527 31641963 436 0
RARA MCF7GSE15244 31799473 31799903 430 0
RARA MCF7GSE15244 31803912 31804189 277 0
RARA MCF7GSE15244 31823416 31824257 841 0
RARA MCF7GSE15244 31824717 31825954 1237 0
RARG MCF7GSE15244 31641494 31642035 541 0
RARG MCF7GSE15244 31803912 31804189 277 0
RARG MCF7GSE15244 31823416 31825954 2538 0
SRF HelaGSE8489 31551091 31551697 606 0
STAT1 HeLaGSE12783 31648230 31649771 1541 0
TFAP2C MCF7GSE21234 31513241 31513775 534 0
TFAP2C MCF7GSE21234 31530142 31530686 544 0
TFAP2C MCF7GSE21234 31576590 31577009 419 0
TFAP2C MCF7GSE21234 31628827 31629570 743 0
TFAP2C MCF7GSE21234 31630245 31630724 479 0
TFAP2C MCF7GSE21234 31645635 31646074 439 0
TFAP2C MCF7GSE21234 31803353 31804368 1015 0
TFAP2C MCF7GSE21234 31820035 31820544 509 0
TFAP2C MCF7GSE21234 31825088 31825716 628 0
TFAP2C MCF7GSE21234 31839168 31839648 480 0
hScc1 BcellGSE12603 31474762 31475055 293 0
hScc1 BcellGSE12603 31545924 31546412 488 0
hScc1 BcellGSE12603 31621952 31622382 430 0
hScc1 BcellGSE12603 31641664 31642035 371 0
hScc1 BcellGSE12603 31803547 31804189 642 0
hScc1 BcellGSE12603 31852568 31853530 962 0
hScc1 CdLSGSE12603 31436863 31437475 612 0
hScc1 CdLSGSE12603 31474721 31475318 597 0
hScc1 CdLSGSE12603 31492660 31493105 445 0
hScc1 CdLSGSE12603 31803442 31804189 747 0
hScc1 G2GSE9613 31641527 31641998 471 0
p63 keratinocytesGSE17611 31592702 31594098 1396 0
p63 keratinocytesGSE17611 31797852 31798756 904 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-21 hsa-mir-21 17 20826792
hsa-miR-21* hsa-mir-21 17 20826792
hsa-miR-31 hsa-mir-31 9 20826792
hsa-miR-31* hsa-mir-31 9 20826792
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16858 EST chr21 31555970 31556645 675 mRNA TIAM1 chr21 31238437 31853161 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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