AutismKB 2.0

Annotation Detail for TLR3


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Basic Information Top
Gene Symbol:TLR3 ( CD283 )
Gene Full Name: toll-like receptor 3
Band: 4q35.1
Quick LinksEntrez ID:7098; OMIM: 603029; Uniprot ID:TLR3_HUMAN; ENSEMBL ID: ENSG00000164342; HGNC ID: 11849
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
52N-linked (GlcNAc...).
57N-linked (GlcNAc...).
70N-linked (GlcNAc...).
124N-linked (GlcNAc...).
196N-linked (GlcNAc...).
247N-linked (GlcNAc...) (Potential).
252N-linked (GlcNAc...).
265N-linked (GlcNAc...).
275N-linked (GlcNAc...).
291N-linked (GlcNAc...).
398N-linked (GlcNAc...).
413N-linked (GlcNAc...).
507N-linked (GlcNAc...).
636N-linked (GlcNAc...).
662N-linked (GlcNAc...) (Potential).
759Phosphotyrosine.
858Phosphotyrosine.
Location(AA) Modifications Resource
52N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
57N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
70N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
124N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
196N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
247N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
252N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
265N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
275N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
291N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
398N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
413N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
507N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
636N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
662N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
759PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
29O-linkedHMM predict
52N-linkedHMM predict
57N-linkedHMM predict
61N-linkedHMM predict
70N-linkedHMM predict
112Phosphoserine(ATM)HMM predict
112Phosphoserine(CK1)HMM predict
124N-linkedHMM predict
205Phosphoserine(CK1)HMM predict
254Phosphoserine(PKG)HMM predict
254Phosphoserine(CAMK2)HMM predict
258Phosphoserine(ATM)HMM predict
258Phosphoserine(IKK)HMM predict
262O-linkedHMM predict
265N-linkedHMM predict
275N-linkedHMM predict
389Phosphoserine(IKK)HMM predict
398N-linkedHMM predict
407Phosphoserine(ATM)HMM predict
413N-linkedHMM predict
417N-linkedHMM predict
420Phosphoserine(PKG)HMM predict
500Phosphoserine(CDC2)HMM predict
507N-linkedHMM predict
636N-linkedHMM predict
662N-linkedHMM predict
667N-linkedHMM predict
735N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003265
  • Location:chr4 187227302-187243243
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 187227212 187227906 694 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-147 hsa-mir-147 9 19721002
hsa-miR-148a hsa-mir-148a 7 21068402
hsa-miR-148a* hsa-mir-148a 7 21068402
hsa-miR-148b hsa-mir-148b 12 21068402
hsa-miR-148b* hsa-mir-148b 12 21068402
hsa-miR-152 hsa-mir-152 17 21068402
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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