AutismKB 2.0

Annotation Detail for TLR5


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Basic Information Top
Gene Symbol:TLR5 ( FLJ10052,MGC126430,MGC126431,SLEB1,TIL3 )
Gene Full Name: toll-like receptor 5
Band: 1q41
Quick LinksEntrez ID:7100; OMIM: 603031; Uniprot ID:TLR5_HUMAN; ENSEMBL ID: ENSG00000187554; HGNC ID: 11851
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
37N-linked (GlcNAc...) (Potential).
46N-linked (GlcNAc...) (Potential).
245N-linked (GlcNAc...) (Potential).
342N-linked (GlcNAc...) (Potential).
422N-linked (GlcNAc...) (Potential).
595N-linked (GlcNAc...) (Potential).
598N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
37N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
46N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
245N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
342N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
422N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
595N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
598N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
37N-linkedHMM predict
46N-linkedHMM predict
79Phosphoserine(ATM)HMM predict
251Phosphoserine(CK1)HMM predict
388Phosphothreonine(PKC)HMM predict
417Phosphothreonine(PKC)HMM predict
422N-linkedHMM predict
426N-linkedHMM predict
464Phosphoserine(ATM)HMM predict
468Phosphothreonine(MAPK)HMM predict
468Phosphothreonine(CDK)HMM predict
474Phosphoserine(CK1)HMM predict
595N-linkedHMM predict
598N-linkedHMM predict
600O-linkedHMM predict
615O-linkedHMM predict
623O-linkedHMM predict
841LysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003268
  • Location:chr1 221350271-221383246
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 221401371 221401726 355 18302
RARA MCF7GSE15244 221383407 221384043 636 479
RARA MCF7GSE15244 221389171 221389707 536 6193
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 221363754 221364046 292 0
CTCF CD4GSE12889 221369264 221369620 356 0
CTCF CD4GSE12889 221373643 221374040 397 0
CTCF CD4SISSRdata 221363754 221364046 292 0
CTCF CD4SISSRdata 221369264 221369620 356 0
CTCF CD4SISSRdata 221373643 221374040 397 0
CTCF G2GSE9613 221363300 221364089 789 0
CTCF G2GSE9613 221369010 221369818 808 0
CTCF G2GSE9613 221373490 221374220 730 0
CTCF G2GSE9613 221376085 221376319 234 0
CTCF G2GSE9613 221382316 221383219 903 0
Myc K562GSE19551 221363630 221363940 310 0
RARA MCF7GSE15244 221374412 221375307 895 0
hScc1 BcellGSE12603 221363576 221363916 340 0
hScc1 BcellGSE12603 221368974 221369677 703 0
hScc1 BcellGSE12603 221373490 221374268 778 0
hScc1 BcellGSE12603 221383063 221383407 344 0
hScc1 CdLSGSE12603 221363469 221364089 620 0
hScc1 CdLSGSE12603 221373490 221374148 658 0
hScc1 G2GSE9613 221363433 221364089 656 0
hScc1 G2GSE9613 221373490 221374305 815 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 21178010
hsa-miR-146a hsa-mir-146a 5 21178010
hsa-miR-146a* hsa-mir-146a 5 21178010
hsa-miR-146a* hsa-mir-146a 5 21178010
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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