AutismKB 2.0

Annotation Detail for TMPO


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TMPO ( CMD1T,LAP2,LEMD4,MGC61508,PRO0868,TP )
Gene Full Name: thymopoietin
Band: 12q23.1
Quick LinksEntrez ID:7112; OMIM: 188380; Uniprot ID:LAP2A_HUMAN; ENSEMBL ID: ENSG00000120802; HGNC ID: 11875
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
66Phosphoserine.
67Phosphoserine.
74Phosphothreonine.
79Phosphoserine.
154Phosphothreonine.
156Phosphoserine.
159Phosphoserine.
160Phosphothreonine.
164Phosphothreonine.
168Phosphoserine.
177Phosphoserine (By similarity).
180Phosphoserine (By similarity).
184Phosphoserine.
196Nuclear localization signal (Potential).
272Phosphoserine.
310Phosphoserine.
351Phosphoserine.
370Phosphoserine.
424Phosphoserine.
656N6-acetyllysine.
Location(AA) Modifications Resource
65PhosphoserinePhospho.ELM 6.0
65PhosphoserinePhospho.ELM 6.0
66PhosphoserinePhospho.ELM 6.0
66PhosphoserinePhospho.ELM 6.0
66Phosphoserine (By similarity).Swiss-Prot 53.0
66Phosphoserine.Swiss-Prot 53.0
67Phosphoserine.Swiss-Prot 53.0
67Phosphoserine (By similarity).Swiss-Prot 53.0
73PhosphothreoninePhospho.ELM 6.0
74Phosphothreonine (By similarity).Swiss-Prot 53.0
74Phosphothreonine (By similarity).Swiss-Prot 53.0
78PhosphoserinePhospho.ELM 6.0
79Phosphoserine.Swiss-Prot 53.0
153PhosphothreoninePhospho.ELM 6.0
155PhosphoserinePhospho.ELM 6.0
155PhosphoserinePhospho.ELM 6.0
156Phosphoserine.Swiss-Prot 53.0
156Phosphoserine (By similarity).Swiss-Prot 53.0
159PhosphothreoninePhospho.ELM 6.0
160Phosphothreonine.Swiss-Prot 53.0
160Phosphothreonine (By similarity).Swiss-Prot 53.0
164Phosphothreonine (By similarity).Swiss-Prot 53.0
166PhosphoserinePhospho.ELM 6.0
167PhosphoserinePhospho.ELM 6.0
167PhosphoserinePhospho.ELM 6.0
168Phosphoserine.Swiss-Prot 53.0
177Phosphoserine (By similarity).Swiss-Prot 53.0
177Phosphoserine (By similarity).Swiss-Prot 53.0
180Phosphoserine (By similarity).Swiss-Prot 53.0
180Phosphoserine (By similarity).Swiss-Prot 53.0
183PhosphoserinePhospho.ELM 6.0
183PhosphoserinePhospho.ELM 6.0
184Phosphoserine.Swiss-Prot 53.0
184Phosphoserine.Swiss-Prot 53.0
305PhosphoserinePhospho.ELM 6.0
306Phosphoserine.Swiss-Prot 53.0
350PhosphoserinePhospho.ELM 6.0
351Phosphoserine.Swiss-Prot 53.0
377PhosphoserinePhospho.ELM 6.0
378Phosphoserine.Swiss-Prot 53.0
424Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
24N-linkedHMM predict
24N-linkedHMM predict
37Phosphotyrosine(EGFR)HMM predict
37Phosphotyrosine(EGFR)HMM predict
67PhosphoserineHMM predict
67PhosphoserineHMM predict
67Phosphoserine(CK2)HMM predict
67Phosphoserine(CK2)HMM predict
96Phosphothreonine(PKA)HMM predict
96Phosphothreonine(PKA)HMM predict
158O-linkedHMM predict
158O-linkedHMM predict
159O-linkedHMM predict
159O-linkedHMM predict
159O-linkedHMM predict
159Phosphoserine(CK1)HMM predict
159Phosphoserine(CK1)HMM predict
159O-linkedHMM predict
160O-linkedHMM predict
160Phosphothreonine(MAPK)HMM predict
160Phosphothreonine(CDK)HMM predict
160Phosphothreonine(CDK)HMM predict
160Phosphothreonine(MAPK)HMM predict
160O-linkedHMM predict
164O-linkedHMM predict
164O-linkedHMM predict
164O-linkedHMM predict
164O-linkedHMM predict
166O-linkedHMM predict
166O-linkedHMM predict
175N-linkedHMM predict
175N-linkedHMM predict
178N-linkedHMM predict
178N-linkedHMM predict
183Phosphotyrosine(INSR)HMM predict
183Phosphotyrosine(INSR)HMM predict
184Phosphoserine(CK1)HMM predict
184Phosphoserine(CK2)HMM predict
184Phosphoserine(CK1)HMM predict
184Phosphoserine(CK2)HMM predict
190Phosphoserine(CK1)HMM predict
208Phosphothreonine(CDK)HMM predict
224Phosphoserine(ATM)HMM predict
228O-linkedHMM predict
235O-linkedHMM predict
235O-linkedHMM predict
257Phosphothreonine(CDK)HMM predict
257Phosphothreonine(PKC)HMM predict
257Phosphothreonine(CDC2)HMM predict
293Phosphoserine(CK1)HMM predict
294Phosphoserine(CK1)HMM predict
294O-linkedHMM predict
296Phosphoserine(IKK)HMM predict
296Phosphoserine(CK1)HMM predict
296Phosphoserine(ATM)HMM predict
296Phosphoserine(CK2)HMM predict
306O-linkedHMM predict
310Phosphoserine(CDK)HMM predict
310Phosphoserine(CDC2)HMM predict
312O-linkedHMM predict
348Phosphoserine(ATM)HMM predict
351Phosphoserine(IKK)HMM predict
354Phosphoserine(CDK)HMM predict
363Phosphoserine(CK1)HMM predict
365Phosphoserine(CK2)HMM predict
365Phosphoserine(CK1)HMM predict
366Phosphoserine(IKK)HMM predict
366Phosphoserine(ATM)HMM predict
366Phosphoserine(CK1)HMM predict
368O-linkedHMM predict
387Phosphoserine(CK1)HMM predict
424Phosphoserine(CDC2)HMM predict
528Phosphothreonine(PKA)HMM predict
560Phosphoserine(IKK)HMM predict
598Phosphoserine(ATM)HMM predict
609Phosphoserine(CK1)HMM predict
622Phosphotyrosine(Syk)HMM predict
627Phosphotyrosine(Jak)HMM predict
645N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001032283
  • Location:chr12 97433539-97466864
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
E2F4 G0GSE7516 97432936 97433877 941 133
FOXA1 MCF7GSE15244 97421038 97422029 991 12006
Fos K562GSE19551 97432981 97433949 968 75
H3K4me3 colorectalcancer 97432086 97433937 1851 528
H3ac HepG2E 97420959 97421697 738 12212
H3ac HepG2E 97430799 97433428 2629 1426
LIN9 SGSE7516 97433020 97433840 820 110
P300 T30-glioblastomaGSE21026 97432984 97433957 973 69
PHF8 293TGSE20725 97432798 97434143 1345 69
PHF8 Hs68minusFBSGSE20725 97420891 97422650 1759 11769
PHF8 Hs68plusFBSGSE20725 97420724 97422565 1841 11895
Pol3 GM12878GSE19551 97421030 97421848 818 12101
Pol3 GM12878GSE19551 97421871 97422611 740 11299
RARA MCF7GSE15244 97420959 97422471 1512 11825
RARG MCF7GSE15244 97420959 97422395 1436 11863
TAF HelaGSE8489 97420316 97420603 287 13080
TAF HelaGSE8489 97420959 97421833 874 12144
TAF HelaGSE8489 97430910 97432018 1108 2076
TAF HelaGSE8489 97432276 97433283 1007 760
TAF k562GSE8489 97420959 97422652 1693 11734
p130 QuiescentGSE19898 97420954 97421568 614 12279
p130 QuiescentGSE19898 97421582 97421919 337 11789
p130 QuiescentGSE19898 97421950 97422167 217 11481
p130 QuiescentGSE19898 97422187 97422363 176 11265
p130 QuiescentGSE19898 97433156 97433727 571 98
p130 SenescentGSE19898 97420819 97422412 1593 11924
p130 SenescentGSE19898 97432757 97433690 933 316
p130 shRbQuiescentGSE19898 97421046 97422319 1273 11857
p130 shRbQuiescentGSE19898 97432891 97434007 1116 91
p130 shRbSenescentGSE19898 97420973 97422354 1381 11876
p130 shRbSenescentGSE19898 97432924 97433844 920 156
p130 G0GSE7516 97432867 97433910 1043 151
p130 SGSE7516 97432973 97433671 698 218
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 97484727 97485001 274 18000
CTCF CD4SISSRdata 97484727 97485001 274 18000
CTCF HelaGSE12889 97484838 97485017 179 18063
CTCF JurkatGSE12889 97484710 97485002 292 17992
CTCF G2GSE9613 97484801 97484989 188 18031
ER Fulvestrant-MCF7GSE14664 97475799 97475892 93 8981
Nanog hESGSE18292 97484783 97484994 211 18024
Oct1 HelaGSE14283 97475820 97475891 71 8991
Sox2 hESGSE18292 97484581 97485005 424 17929
hScc1 BcellGSE12603 97484801 97484989 188 18031
hScc1 CdLSGSE12603 97484733 97484989 256 17997
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 97457276 97457447 171 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
6479 mRNA TMPO chr12 97411909 97430789 390 mRNA chr12 97411158 97412416Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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