AutismKB 2.0

Annotation Detail for TMPRSS2


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Basic Information Top
Gene Symbol:TMPRSS2 ( FLJ41954,PP9284,PRSS10 )
Gene Full Name: transmembrane protease, serine 2
Band: 21q22.3
Quick LinksEntrez ID:7113; OMIM: 602060; Uniprot ID:TMPS2_HUMAN; ENSEMBL ID: ENSG00000184012; HGNC ID: 11876
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
213N-linked (GlcNAc...) (Potential).
249N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
213N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
249N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
7Phosphoserine(ATM)HMM predict
20Phosphotyrosine(Syk)HMM predict
20Phosphotyrosine(SRC)HMM predict
20Phosphotyrosine(INSR)HMM predict
26Phosphotyrosine(Syk)HMM predict
31O-linkedHMM predict
37Phosphotyrosine(Abl)HMM predict
47Phosphoserine(CDK)HMM predict
47Phosphoserine(MAPK)HMM predict
47Phosphoserine(CDC2)HMM predict
47O-linkedHMM predict
67O-linkedHMM predict
71Phosphoserine(IKK)HMM predict
71Phosphoserine(CDK)HMM predict
71Phosphoserine(CDC2)HMM predict
75O-linkedHMM predict
128N-linkedHMM predict
131N-linkedHMM predict
163Phosphoserine(ATM)HMM predict
163Phosphoserine(CDK)HMM predict
204Phosphoserine(IKK)HMM predict
249N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005656
  • Location:chr21 41758350-41801947
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 41814501 41815515 1014 13061
RARG MCF7GSE15244 41814501 41814994 493 12800
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 41781488 41782760 1272 0
CBP T30-glioblastomaGSE21026 41760925 41761793 868 0
FOXA1 MCF7GSE15244 41792411 41792810 399 0
FOXA1 MCF7GSE15244 41794119 41795084 965 0
Nanog hESGSE18292 41771811 41772127 316 0
P300 T30-glioblastomaGSE21026 41760820 41761866 1046 0
RARA MCF7GSE15244 41794119 41795084 965 0
RARA MCF7GSE15244 41795440 41796613 1173 0
RARG MCF7GSE15244 41794191 41795084 893 0
RARG MCF7GSE15244 41795440 41796613 1173 0
RARG MCF7GSE15244 41799979 41800809 830 0
TFAP2C MCF7GSE21234 41799808 41800902 1094 0
hScc1 BcellGSE12603 41762367 41762856 489 0
hScc1 BcellGSE12603 41764143 41764605 462 0
hScc1 BcellGSE12603 41782052 41782399 347 0
hScc1 BcellGSE12603 41787781 41788203 422 0
hScc1 BcellGSE12603 41800541 41801288 747 0
hScc1 BcellGSE12603 41801578 41801874 296 0
hScc1 CdLSGSE12603 41769674 41770271 597 0
p130 QuiescentGSE19898 41761325 41761523 198 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-221 hsa-mir-221 X 21378318
hsa-miR-221* hsa-mir-221 X 21378318
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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