AutismKB 2.0

Annotation Detail for TNFAIP1


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Basic Information Top
Gene Symbol:TNFAIP1 ( B12,B61,EDP1,MGC2317,hBACURD2 )
Gene Full Name: tumor necrosis factor, alpha-induced protein 1 (endothelial)
Band: 17q11.2
Quick LinksEntrez ID:7126; OMIM: 191161; Uniprot ID:BACD2_HUMAN; ENSEMBL ID: ENSG00000109079; HGNC ID: 11894
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
278Phosphoserine.
280Phosphoserine; by CK2.
285Phosphothreonine.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021137
  • Location:chr17 23686912-23698159
  • strand:+
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 23693854 23695640 1786 0
H3K4me2 HCT116GSE10453 23687742 23688368 626 0
H3K4me3 colorectalcancer 23687566 23688012 446 0
H3ac HepG2E 23687708 23688899 1191 0
Rb GrowingGSE19898 23686726 23687112 386 0
TFAP2C MCF7GSE21234 23687048 23688021 973 0
VDR GM10861-stimGSE22484 23693663 23699632 5969 0
p130 QuiescentGSE19898 23686852 23687682 830 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 15685193
hsa-miR-1 hsa-mir-1-1 20 15685193
hsa-miR-124 hsa-mir-124-1 8 15685193
hsa-miR-124 hsa-mir-124-2 8 15685193
hsa-miR-124 hsa-mir-124-3 20 15685193
hsa-miR-373 hsa-mir-373 19 15685193
hsa-miR-373* hsa-mir-373 19 15685193
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
685 Unknown MicroArray miR-373 TNFAIP1 n_a 15685193
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000109079 n_a n_a n_a "epithelium, squamous cell, leukocyte, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
10844 mRNA TNFAIP1 chr17 23686912 23698160 374 mRNA POLDIP2 chr17 23697786 23708693Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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