AutismKB 2.0

Annotation Detail for TNFAIP2


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Basic Information Top
Gene Symbol:TNFAIP2 ( B94 )
Gene Full Name: tumor necrosis factor, alpha-induced protein 2
Band: 14q32
Quick LinksEntrez ID:7127; OMIM: 603300; Uniprot ID:TNAP2_HUMAN; ENSEMBL ID: ENSG00000185215; HGNC ID: 11895
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
6Phosphoserine(CK1)HMM predict
78Phosphothreonine(PKC)HMM predict
123Phosphoserine(PKG)HMM predict
176O-linkedHMM predict
275Phosphotyrosine(INSR)HMM predict
507Phosphoserine(CK1)HMM predict
621N-linkedHMM predict
624N-linkedHMM predict
651IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006291
  • Location:chr14 102662416-102673528
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102659183 102659547 364 3052
CTCF G2GSE9613 102659882 102660274 392 2339
NFkBII GM12878GSE19485 102657967 102659301 1334 3783
STAT1 HeLaGSE12782 102653766 102655452 1686 7808
STAT1 HeLaGSE12783 102653873 102655472 1599 7744
hScc1 BcellGSE12603 102658681 102659402 721 3375
hScc1 BcellGSE12603 102659701 102660236 535 2448
p130 shRbQuiescentGSE19898 102659774 102660181 407 2439
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF JurkatGSE12889 102677383 102677580 197 3953
CTCF G2GSE9613 102675025 102675225 200 1597
CTCF G2GSE9613 102691377 102691790 413 18055
NFkBII GM10847GSE19485 102675996 102677972 1976 3456
NFkBII GM12878GSE19485 102675803 102678143 2340 3445
NFkBII GM12892GSE19485 102675679 102678059 2380 3341
NFkBII GM18526GSE19485 102676050 102678069 2019 3531
Oct1 HelaGSE14283 102682125 102682168 43 8618
RARA MCF7GSE15244 102691341 102691790 449 18037
RNAII Tamoxifen-MCF7GSE14664 102687976 102688052 76 14486
TFAP2C MCF7GSE21234 102691147 102691535 388 17813
TFAP2C MCF7GSE21234 102692610 102693383 773 19468
hScc1 BcellGSE12603 102674474 102675129 655 1273
hScc1 BcellGSE12603 102677081 102677617 536 3821
hScc1 BcellGSE12603 102691414 102692127 713 18242
hScc1 CdLSGSE12603 102677151 102677829 678 3962
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 102662546 102663144 598 0
CTCF G2GSE9613 102665643 102666488 845 0
CTCF G2GSE9613 102666907 102667267 360 0
CTCF G2GSE9613 102668805 102668978 173 0
Fos K562GSE19551 102672625 102673526 901 0
RARG MCF7GSE15244 102667052 102667565 513 0
TFAP2C MCF7GSE21234 102665710 102666549 839 0
TFAP2C MCF7GSE21234 102666560 102667710 1150 0
hScc1 BcellGSE12603 102667832 102668195 363 0
hScc1 BcellGSE12603 102669542 102669886 344 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1298 Unknown pSILAC miR-30 TNFAIP2 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000185215 n_a n_a n_a "epithelium, lymphocyte, leukocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, leukaemia, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018