AutismKB 2.0

Annotation Detail for TNFAIP3


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Basic Information Top
Gene Symbol:TNFAIP3 ( A20,MGC104522,MGC138687,MGC138688,OTUD7C,TNFA1P2 )
Gene Full Name: tumor necrosis factor, alpha-induced protein 3
Band: 6q23.3
Quick LinksEntrez ID:7128; OMIM: 191163; Uniprot ID:TNAP3_HUMAN; ENSEMBL ID: ENSG00000118503; HGNC ID: 11896
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
459Phosphoserine.
575Phosphoserine.
Location(AA) Modifications Resource
568PhosphoserinePhospho.ELM 6.0
575Phosphoserine.Swiss-Prot 53.0
575PhosphoserinePhospho.ELM 6.0
645PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
179Phosphothreonine(MAPK)HMM predict
262Phosphothreonine(PKC)HMM predict
266Phosphoserine(CK2)HMM predict
443Phosphotyrosine(INSR)HMM predict
459O-linkedHMM predict
544O-linkedHMM predict
548O-linkedHMM predict
549Phosphoserine(CK1)HMM predict
550Phosphoserine(IKK)HMM predict
550Phosphoserine(CK1)HMM predict
550O-linkedHMM predict
550O-linkedHMM predict
552Phosphoserine(CK1)HMM predict
552O-linkedHMM predict
553O-linkedHMM predict
554Phosphoserine(IKK)HMM predict
554O-linkedHMM predict
565Phosphoserine(PKB)HMM predict
565Phosphoserine(PKA)HMM predict
573Phosphoserine(CDC2)HMM predict
597Phosphothreonine(MAPK)HMM predict
597Phosphothreonine(CDK)HMM predict
604Phosphothreonine(PKC)HMM predict
617Phosphothreonine(CDC2)HMM predict
645Phosphoserine(CDC2)HMM predict
645Phosphoserine(IKK)HMM predict
692Phosphothreonine(CK2)HMM predict
699Phosphoserine(ATM)HMM predict
711O-linkedHMM predict
749MethylarginineHMM predict
776AsparagineHMM predict
778TyrosineHMM predict
779CysteineHMM predict
780AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006290
  • Location:chr6 138230273-138246137
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 138229908 138230198 290 221
CTCF CD4SISSRdata 138229908 138230198 290 221
CTCF G2GSE9613 138229613 138230665 1052 135
PAX3-FKHR Rh4GSE19063 138215073 138217423 2350 14026
SRF HelaGSE8489 138211463 138213879 2416 17603
SRF HelaGSE8489 138214424 138216352 1928 14886
SRF k562GSE8489 138209925 138211059 1134 19782
SRF k562GSE8489 138211463 138213879 2416 17603
SRF k562GSE8489 138214424 138215406 982 15359
TAF k562GSE8489 138223794 138226687 2893 5033
USF1 HepG2E 138228644 138229832 1188 1036
hScc1 BcellGSE12603 138229383 138230945 1562 110
hScc1 CdLSGSE12603 138229319 138230665 1346 282
p130 QuiescentGSE19898 138229966 138230187 221 197
p130 SenescentGSE19898 138229312 138229695 383 770
p130 SenescentGSE19898 138229951 138230213 262 192
p130 shRbSenescentGSE19898 138229937 138230313 376 149
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 138242792 138245057 2265 0
CTCF G2GSE9613 138232086 138232532 446 0
CTCF G2GSE9613 138241629 138242157 528 0
H3K4me3 colorectalcancer 138230945 138232675 1730 0
H3ac HepG2E 138230454 138234844 4390 0
NFkBII GM10847GSE19485 138228816 138231770 2954 0
NFkBII GM10847GSE19485 138235521 138237642 2121 0
NFkBII GM12878GSE19485 138228794 138241681 12887 0
NFkBII GM12892GSE19485 138228899 138238289 9390 0
NFkBII GM15510GSE19485 138228851 138237833 8982 0
NFkBII GM18505GSE19485 138228779 138232913 4134 0
NFkBII GM18505GSE19485 138234842 138237653 2811 0
NFkBII GM18526GSE19485 138229019 138238368 9349 0
Nanog hESGSE18292 138242727 138242991 264 0
USF1 HepG2E 138230491 138232710 2219 0
USF2 HepG2E 138230518 138231610 1092 0
VDR GM10861-stimGSE22484 138228782 138247721 18939 0
hScc1 BcellGSE12603 138232050 138232496 446 0
hScc1 CdLSGSE12603 138232012 138232888 876 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-17 hsa-mir-17 13 20014148
hsa-miR-17* hsa-mir-17 13 20014148
hsa-miR-92a hsa-mir-92a-1 13 20014148
hsa-miR-92a hsa-mir-92a-2 X 20014148
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23232 HTC TNFAIP3 chr6 138230416 138246143 95 mRNA chr6 138186504 138231063Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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