AutismKB 2.0

Annotation Detail for TNS1


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Basic Information Top
Gene Symbol:TNS1 ( DKFZp586K0617,MGC88584,MST091,MST122,MST127,MSTP122,MSTP127,MXRA6,TNS )
Gene Full Name: tensin 1
Band: 2q35
Quick LinksEntrez ID:7145; OMIM: 600076; Uniprot ID:TENS1_HUMAN; ENSEMBL ID: ENSG00000079308; HGNC ID: 11973
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
327Phosphotyrosine.
338Phosphoserine.
339Phosphotyrosine.
366Phosphotyrosine.
445Phosphoserine.
733Phosphoserine.
746Phosphoserine.
796Phosphotyrosine.
858Phosphoserine.
903Phosphotyrosine.
1048Phosphoserine.
1107Phosphothreonine.
1124Phosphoserine.
1149Phosphotyrosine.
1155Phosphoserine.
1157Phosphoserine.
1177Phosphoserine.
1189Phosphothreonine.
1192Phosphoserine.
1254Phosphotyrosine.
1266Phosphothreonine.
1269Phosphoserine.
1297Phosphoserine.
1314Phosphoserine.
1323Phosphotyrosine.
1326Phosphotyrosine.
1328Phosphothreonine.
1381Phosphoserine.
1404Phosphotyrosine.
1446Phosphoserine.
Location(AA) Modifications Resource
1297Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
231Phosphoserine(IKK)HMM predict
257Phosphoserine(CDC2)HMM predict
257PhosphoserineHMM predict
297Phosphotyrosine(EGFR)HMM predict
328N-linkedHMM predict
341N-linkedHMM predict
383N-linkedHMM predict
388O-linkedHMM predict
388Phosphothreonine(PKA)HMM predict
390O-linkedHMM predict
392Phosphothreonine(MAPK)HMM predict
401Phosphoserine(CK1)HMM predict
404Phosphoserine(CK1)HMM predict
406O-linkedHMM predict
408N-linkedHMM predict
412O-linkedHMM predict
426O-linkedHMM predict
429O-linkedHMM predict
429O-linkedHMM predict
476O-linkedHMM predict
476Phosphoserine(CDK)HMM predict
527N-linkedHMM predict
538Phosphoserine(CDC2)HMM predict
581Phosphoserine(PKG)HMM predict
621Phosphoserine(IKK)HMM predict
681Phosphoserine(CDC2)HMM predict
681Phosphoserine(MAPK)HMM predict
701Phosphoserine(PKG)HMM predict
742O-linkedHMM predict
742Phosphoserine(CDC2)HMM predict
746O-linkedHMM predict
746Phosphoserine(ATM)HMM predict
766Phosphotyrosine(INSR)HMM predict
772Phosphoserine(IKK)HMM predict
775O-linkedHMM predict
783O-linkedHMM predict
813Phosphoserine(CDC2)HMM predict
813Phosphoserine(CDK)HMM predict
813Phosphoserine(IKK)HMM predict
828O-linkedHMM predict
828Phosphoserine(CDC2)HMM predict
828Phosphoserine(CDK)HMM predict
828Phosphoserine(IKK)HMM predict
838O-linkedHMM predict
838Phosphoserine(MAPK)HMM predict
849Phosphoserine(CDC2)HMM predict
849Phosphoserine(MAPK)HMM predict
860Phosphothreonine(CDC2)HMM predict
860Phosphothreonine(MAPK)HMM predict
860Phosphothreonine(CDK)HMM predict
860PhosphothreonineHMM predict
899Phosphoserine(PKG)HMM predict
903Phosphotyrosine(INSR)HMM predict
903Phosphotyrosine(Syk)HMM predict
903PhosphotyrosineHMM predict
905N-linkedHMM predict
912O-linkedHMM predict
912Phosphoserine(CDC2)HMM predict
912Phosphoserine(MAPK)HMM predict
912Phosphoserine(CDK)HMM predict
912Phosphoserine(IKK)HMM predict
915Phosphoserine(CDC2)HMM predict
960O-linkedHMM predict
960Phosphoserine(CDK)HMM predict
960Phosphoserine(IKK)HMM predict
962O-linkedHMM predict
963O-linkedHMM predict
963Phosphoserine(ATM)HMM predict
967O-linkedHMM predict
971Phosphoserine(CDC2)HMM predict
978Phosphothreonine(CDK)HMM predict
1019Phosphoserine(CK2)HMM predict
1025Phosphotyrosine(EGFR)HMM predict
1046Phosphoserine(IKK)HMM predict
1063N-linkedHMM predict
1074O-linkedHMM predict
1074Phosphoserine(CDC2)HMM predict
1074Phosphoserine(CDK)HMM predict
1074Phosphoserine(IKK)HMM predict
1077Phosphoserine(IKK)HMM predict
1078O-linkedHMM predict
1078O-linkedHMM predict
1105Phosphothreonine(MAPK)HMM predict
1105Phosphothreonine(CDK)HMM predict
1107Phosphothreonine(PKA)HMM predict
1119O-linkedHMM predict
1119Phosphoserine(IKK)HMM predict
1135Phosphoserine(CDC2)HMM predict
1135Phosphoserine(CDK)HMM predict
1139O-linkedHMM predict
1139Phosphothreonine(PKC)HMM predict
1145Phosphoserine(CK2)HMM predict
1146Phosphoserine(CDC2)HMM predict
1146Phosphoserine(ATM)HMM predict
1149SulfotyrosineHMM predict
1157Phosphoserine(CDC2)HMM predict
1160Phosphoserine(ATM)HMM predict
1177Phosphoserine(CDC2)HMM predict
1189Phosphothreonine(MAPK)HMM predict
1192O-linkedHMM predict
1192Phosphoserine(CDC2)HMM predict
1208O-linkedHMM predict
1209O-linkedHMM predict
1209Phosphoserine(IKK)HMM predict
1211O-linkedHMM predict
1211Phosphoserine(CK1)HMM predict
1228O-linkedHMM predict
1231Phosphoserine(IKK)HMM predict
1232Phosphoserine(CDC2)HMM predict
1235O-linkedHMM predict
1235O-linkedHMM predict
1235Phosphoserine(IKK)HMM predict
1236O-linkedHMM predict
1236O-linkedHMM predict
1239O-linkedHMM predict
1240O-linkedHMM predict
1240Phosphothreonine(CDC2)HMM predict
1240Phosphothreonine(MAPK)HMM predict
1240Phosphothreonine(CDK)HMM predict
1243Phosphoserine(IKK)HMM predict
1266Phosphothreonine(CDC2)HMM predict
1266Phosphothreonine(MAPK)HMM predict
1271O-linkedHMM predict
1289O-linkedHMM predict
1294Phosphoserine(CDC2)HMM predict
1294Phosphoserine(MAPK)HMM predict
1297Phosphoserine(IKK)HMM predict
1328Phosphothreonine(CDK)HMM predict
1335Phosphothreonine(PKA)HMM predict
1335Phosphothreonine(PKC)HMM predict
1341Phosphoserine(PKG)HMM predict
1345Phosphotyrosine(Syk)HMM predict
1349O-linkedHMM predict
1364O-linkedHMM predict
1365Phosphoserine(CDC2)HMM predict
1368O-linkedHMM predict
1369O-linkedHMM predict
1369Phosphoserine(CDC2)HMM predict
1369Phosphoserine(MAPK)HMM predict
1369Phosphoserine(ATM)HMM predict
1369PhosphoserineHMM predict
1371Phosphoserine(CDC2)HMM predict
1371Phosphoserine(CDK)HMM predict
1381O-linkedHMM predict
1393Phosphoserine(PKG)HMM predict
1404Phosphotyrosine(INSR)HMM predict
1413Phosphoserine(CDC2)HMM predict
1413Phosphoserine(MAPK)HMM predict
1417O-linkedHMM predict
1417O-linkedHMM predict
1421Phosphoserine(CDC2)HMM predict
1421Phosphoserine(CDK)HMM predict
1421Phosphoserine(ATM)HMM predict
1423O-linkedHMM predict
1423Phosphoserine(IKK)HMM predict
1427O-linkedHMM predict
1429Phosphoserine(IKK)HMM predict
1440Phosphotyrosine(Syk)HMM predict
1504Phosphoserine(PKG)HMM predict
1583Phosphoserine(IKK)HMM predict
1587N-linkedHMM predict
1619O-linkedHMM predict
1625O-linkedHMM predict
1631O-linkedHMM predict
1631Phosphothreonine(MAPK)HMM predict
1699Phosphoserine(IKK)HMM predict
1700Phosphothreonine(CK2)HMM predict
1731AlanineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_022648
  • Location:chr2 218375756-218517005
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 218519880 218520510 630 3190
CTCF G2GSE9613 218523298 218523660 362 6474
CTCF G2GSE9613 218525798 218526133 335 8960
CTCF G2GSE9613 218527835 218528640 805 11232
CTCF G2GSE9613 218536048 218536360 312 19199
TFAP2C MCF7GSE21234 218516933 218517732 799 327
TFAP2C MCF7GSE21234 218524349 218524959 610 7649
TFAP2C MCF7GSE21234 218527333 218528011 678 10667
TFAP2C MCF7GSE21234 218528042 218528722 680 11377
hScc1 BcellGSE12603 218516867 218517172 305 14
hScc1 G2GSE9613 218536048 218536360 312 19199
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 218358427 218358816 389 17135
CTCF CD4GSE12889 218362203 218362516 313 13397
CTCF CD4SISSRdata 218358427 218358816 389 17135
CTCF CD4SISSRdata 218362203 218362516 313 13397
CTCF JurkatGSE12889 218362251 218362521 270 13371
CTCF G2GSE9613 218357854 218359227 1373 17216
CTCF G2GSE9613 218361725 218362864 1139 13462
CTCF G2GSE9613 218370090 218370512 422 5456
CTCF G2GSE9613 218372845 218373112 267 2778
NRSF JurkatGSE13047 218370735 218371053 318 4863
NRSF-mono JurkatQuESTdata 218370735 218371081 346 4849
STAT1 HeLaGSE12783 218361707 218362715 1008 13546
STAT1 IFNSISSRdata 218362093 218362684 591 13368
hScc1 BcellGSE12603 218358311 218359192 881 17005
hScc1 BcellGSE12603 218362097 218362832 735 13292
hScc1 CdLSGSE12603 218358215 218358826 611 17236
hScc1 CdLSGSE12603 218361957 218362628 671 13464
hScc1 G2GSE9613 218358180 218358864 684 17235
hScc1 G2GSE9613 218361725 218362628 903 13580
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 218459643 218460063 420 0
CTCF CD4SISSRdata 218459643 218460063 420 0
CTCF HelaGSE12889 218472580 218472829 249 0
CTCF JurkatGSE12889 218472519 218472758 239 0
CTCF JurkatGSE12889 218491277 218491502 225 0
CTCF G2GSE9613 218376258 218376552 294 0
CTCF G2GSE9613 218377456 218377796 340 0
CTCF G2GSE9613 218378895 218379261 366 0
CTCF G2GSE9613 218386174 218386475 301 0
CTCF G2GSE9613 218390452 218391590 1138 0
CTCF G2GSE9613 218393911 218394086 175 0
CTCF G2GSE9613 218395760 218396955 1195 0
CTCF G2GSE9613 218398718 218399005 287 0
CTCF G2GSE9613 218401015 218401454 439 0
CTCF G2GSE9613 218403091 218403554 463 0
CTCF G2GSE9613 218404290 218404650 360 0
CTCF G2GSE9613 218407079 218407214 135 0
CTCF G2GSE9613 218407702 218407886 184 0
CTCF G2GSE9613 218409921 218410470 549 0
CTCF G2GSE9613 218411559 218413061 1502 0
CTCF G2GSE9613 218413635 218414235 600 0
CTCF G2GSE9613 218417237 218417443 206 0
CTCF G2GSE9613 218420550 218420815 265 0
CTCF G2GSE9613 218421511 218421881 370 0
CTCF G2GSE9613 218423485 218423799 314 0
CTCF G2GSE9613 218425887 218426684 797 0
CTCF G2GSE9613 218431028 218431827 799 0
CTCF G2GSE9613 218436732 218437129 397 0
CTCF G2GSE9613 218439174 218439731 557 0
CTCF G2GSE9613 218442580 218442757 177 0
CTCF G2GSE9613 218443929 218444323 394 0
CTCF G2GSE9613 218444838 218445142 304 0
CTCF G2GSE9613 218448975 218449428 453 0
CTCF G2GSE9613 218451230 218452171 941 0
CTCF G2GSE9613 218453472 218453793 321 0
CTCF G2GSE9613 218455026 218455164 138 0
CTCF G2GSE9613 218459390 218460142 752 0
CTCF G2GSE9613 218462785 218462957 172 0
CTCF G2GSE9613 218463603 218463787 184 0
CTCF G2GSE9613 218468070 218468379 309 0
CTCF G2GSE9613 218470052 218471111 1059 0
CTCF G2GSE9613 218471388 218471536 148 0
CTCF G2GSE9613 218472076 218473288 1212 0
CTCF G2GSE9613 218473700 218474054 354 0
CTCF G2GSE9613 218475670 218476051 381 0
CTCF G2GSE9613 218476994 218477531 537 0
CTCF G2GSE9613 218480046 218480291 245 0
CTCF G2GSE9613 218481611 218482448 837 0
CTCF G2GSE9613 218482966 218483379 413 0
CTCF G2GSE9613 218485731 218486977 1246 0
CTCF G2GSE9613 218489200 218489437 237 0
CTCF G2GSE9613 218491095 218491770 675 0
CTCF G2GSE9613 218492043 218492711 668 0
CTCF G2GSE9613 218495256 218495522 266 0
CTCF G2GSE9613 218501048 218501969 921 0
CTCF G2GSE9613 218505650 218506622 972 0
CTCF G2GSE9613 218507253 218507832 579 0
CTCF G2GSE9613 218508935 218509296 361 0
CTCF G2GSE9613 218510812 218511470 658 0
CTCF G2GSE9613 218512266 218512514 248 0
CTCF G2GSE9613 218512747 218513020 273 0
CTCF G2GSE9613 218513805 218514462 657 0
CTCF G2GSE9613 218516317 218517137 820 0
ER MCF7GSE19013 218516370 218517599 1229 0
Fos K562GSE19551 218460642 218461071 429 0
HIF1 HypoHepG2 218475377 218476534 1157 0
NRSF JurkatGSE13047 218377319 218377869 550 0
NRSF-mono JurkatQuESTdata 218377357 218377812 455 0
NRSF-poly JurkatQuESTdata 218377262 218377835 573 0
Nanog hESGSE18292 218409178 218409506 328 0
Nanog hESGSE18292 218508683 218508955 272 0
P300 T30-glioblastomaGSE21026 218423106 218423934 828 0
Rb GrowingGSE19898 218472543 218472679 136 0
Rb SenescentGSE19898 218472555 218472870 315 0
Rb shRbQuiescentGSE19898 218468378 218468563 185 0
TFAP2C MCF7GSE21234 218492051 218492662 611 0
USF1 HepG2E 218473566 218474383 817 0
USF1 HepG2E 218474953 218478668 3715 0
USF2 HepG2E 218474988 218476994 2006 0
hScc1 BcellGSE12603 218396610 218396955 345 0
hScc1 BcellGSE12603 218407079 218407287 208 0
hScc1 BcellGSE12603 218442401 218442721 320 0
hScc1 BcellGSE12603 218459682 218460142 460 0
hScc1 BcellGSE12603 218506191 218506549 358 0
hScc1 CdLSGSE12603 218459086 218460108 1022 0
hScc1 G2GSE9613 218451230 218451969 739 0
hScc1 G2GSE9613 218459050 218460108 1058 0
hScc1 G2GSE9613 218505650 218505832 182 0
hScc1 G2GSE9613 218506092 218506549 457 0
hScc1 G2GSE9613 218507384 218507832 448 0
p130 QuiescentGSE19898 218462937 218463209 272 0
p130 QuiescentGSE19898 218472540 218472707 167 0
p130 shRbSenescentGSE19898 218502243 218502417 174 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
15641 mRNA chr2 218649456 218649902 446 mRNA TNS1 chr2 218490030 218669048 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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