AutismKB 2.0

Annotation Detail for TPI1


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Basic Information Top
Gene Symbol:TPI1 ( MGC88108,TPI )
Gene Full Name: triosephosphate isomerase 1
Band: 12p13.31
Quick LinksEntrez ID:7167; OMIM: 190450; Uniprot ID:TPIS_HUMAN; ENSEMBL ID: ENSG00000111669; HGNC ID: 12009
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
14N6-acetyllysine.
21Phosphoserine.
80Phosphoserine.
188N6-acetyllysine.
194N6-acetyllysine.
238N6-acetyllysine.
Location(AA) Modifications Resource
20PhosphoserinePhospho.ELM 6.0
21Phosphoserine.Swiss-Prot 53.0
188N6-acetyllysine.Swiss-Prot 53.0
Location(AA) Modification Resource
21Phosphoserine(PKG)HMM predict
21Phosphoserine(CAMK2)HMM predict
176O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000365
  • Location:chr12 6846966-6850252
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
p130 shRbQuiescentGSE19898 6846504 6846791 287 319
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 6846914 6847711 797 0
CTCF G2GSE9613 6848345 6849407 1062 0
FOXA1 MCF7GSE15244 6848506 6848975 469 0
H3K4me3 colorectalcancer 6847818 6848110 292 0
H3ac HepG2E 6847894 6849129 1235 0
Oct1 H2O2-HelaGSE14283 6848590 6848617 27 0
PHF8 HeLaGSE20725 6846201 6847919 1718 0
RARA MCF7GSE15244 6848506 6849407 901 0
RARG MCF7GSE15244 6848506 6849593 1087 0
hScc1 BcellGSE12603 6846950 6847678 728 0
hScc1 CdLSGSE12603 6846789 6847522 733 0
p130 SenescentGSE19898 6846909 6847141 232 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018