Annotation Detail for TPM2
Basic Information Top
| Gene Symbol: | TPM2 ( AMCD1,DA1,DA2B,NEM4,TMSB ) |
|---|---|
| Gene Full Name: | tropomyosin 2 (beta) |
| Band: | 9p13.3 |
| Quick Links | Entrez ID:7169; OMIM: 190990; Uniprot ID:TPM2_HUMAN; ENSEMBL ID: ENSG00000198467; HGNC ID: 12011 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 1 | N-acetylmethionine (By similarity). | |
| 252 | Phosphothreonine (By similarity). | |
| 283 | Phosphoserine (By similarity). | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 1 | N-acetylmethionine (By similarity). | Swiss-Prot 53.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 79 | Phosphothreonine(CK2) | HMM predict |
| 162 | Phosphotyrosine(Syk) | HMM predict |
| 179 | Phosphoserine(CK1) | HMM predict |
| 188 | Phosphoserine(CK2) | HMM predict |
| 215 | Phosphoserine(CK2) | HMM predict |
| 216 | Phosphothreonine(PKC) | HMM predict |
| 221 | Phosphotyrosine(EGFR) | HMM predict |
| 221 | Phosphotyrosine(INSR) | HMM predict |
| 261 | Phosphotyrosine(Abl) | HMM predict |
| 261 | Phosphotyrosine(Syk) | HMM predict |
| 277 | Alanine | HMM predict |
- RefSeq ID: NM_003289
- Location:chr9 35672923-35680052
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| PHF8 | HeLa | GSE20725 | 35679141 | 35681634 | 2493 | 335 |
| p130 | Senescent | GSE19898 | 35681121 | 35681423 | 302 | 1220 |
| p130 | shRbQuiescent | GSE19898 | 35681193 | 35681441 | 248 | 1265 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| Nanog | hES | GSE18292 | 35678753 | 35678983 | 230 | 0 |
| Rb | Growing | GSE19898 | 35679813 | 35680019 | 206 | 0 |
| p130 | Quiescent | GSE19898 | 35679823 | 35680056 | 233 | 0 |
| Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
|---|---|---|---|
| hsa-let-7b | hsa-let-7b | 22 | 18668040 |
| hsa-let-7b* | hsa-let-7b | 22 | 18668040 |
| hsa-miR-1 | hsa-mir-1-2 | 18 | 18668040 |
| hsa-miR-1 | hsa-mir-1-1 | 20 | 18668040 |
| hsa-miR-155 | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-155* | hsa-mir-155 | 21 | 18668040 |
| hsa-miR-16 | hsa-mir-16-1 | 13 | 18668040 |
| hsa-miR-16 | hsa-mir-16-2 | 3 | 18668040 |
| hsa-miR-30a | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30a* | hsa-mir-30a | 6 | 18668040 |
| hsa-miR-30b | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30b* | hsa-mir-30b | 8 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30c | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-1* | hsa-mir-30c-1 | 1 | 18668040 |
| hsa-miR-30c-2* | hsa-mir-30c-2 | 6 | 18668040 |
| hsa-miR-30d | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30d* | hsa-mir-30d | 8 | 18668040 |
| hsa-miR-30e | hsa-mir-30e | 1 | 18668040 |
| hsa-miR-30e* | hsa-mir-30e | 1 | 18668040 |
| ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
|---|---|---|---|---|---|---|
| 932 | Unknown | pSILAC | LNA_let-7b | TPM2 | up 25-50% | 18668040 |
| 1207 | Unknown | pSILAC | miR-1 | TPM2 | down 50-25% | 18668040 |
| Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
| ENSG00000198467 | n_a | n_a | n_a | "lymphocyte, muscle cell" | malignant tumour | |
| ENSG00000198467 | n_a | n_a | n_a | "lymphocyte, muscle cell" | malignant tumour |
Cis-Nats regulation