AutismKB 2.0

Annotation Detail for C2


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Basic Information Top
Gene Symbol:C2 ( CO2,DKFZp779M0311 )
Gene Full Name: complement component 2
Band: 6p21.33
Quick LinksEntrez ID:717; OMIM: 217000; Uniprot ID:CO2_HUMAN; ENSEMBL ID: ENSG00000166278; HGNC ID: 1248
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
29N-linked (GlcNAc...) (Potential).
112N-linked (GlcNAc...).
290N-linked (GlcNAc...) (Potential).
333N-linked (GlcNAc...).
467N-linked (GlcNAc...).
471N-linked (GlcNAc...).
621N-linked (GlcNAc...).
651N-linked (GlcNAc...).
Location(AA) Modifications Resource
29N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
112N-linked (GlcNAc...).Swiss-Prot 53.0
290N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
333N-linked (GlcNAc...).Swiss-Prot 53.0
467N-linked (GlcNAc...).Swiss-Prot 53.0
471N-linked (GlcNAc...).Swiss-Prot 53.0
621N-linked (GlcNAc...).Swiss-Prot 53.0
651N-linked (GlcNAc...).Swiss-Prot 53.0
Location(AA) Modification Resource
49Phosphotyrosine(INSR)HMM predict
58Phosphoserine(CDK)HMM predict
58PhosphoserineHMM predict
58Phosphoserine(CDC2)HMM predict
72Phosphothreonine(MAPK)HMM predict
106Phosphoserine(PKB)HMM predict
157O-linkedHMM predict
232N-linkedHMM predict
262Phosphoserine(ATM)HMM predict
328Phosphotyrosine(EGFR)HMM predict
333N-linkedHMM predict
338N-linkedHMM predict
339O-linkedHMM predict
405Phosphotyrosine(INSR)HMM predict
405Phosphotyrosine(Syk)HMM predict
471N-linkedHMM predict
478Phosphothreonine(CDC2)HMM predict
478Phosphothreonine(MAPK)HMM predict
488Phosphoserine(IKK)HMM predict
621N-linkedHMM predict
626N-linkedHMM predict
651N-linkedHMM predict
715MethyllysineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000063
  • Location:chr6 32003472-32021426
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 31998802 31998969 167 4587
CTCF CD4SISSRdata 31998802 31998969 167 4587
CTCF G2GSE9613 31996117 31996365 248 7232
CTCF G2GSE9613 31998993 31999200 207 4376
hScc1 CdLSGSE12603 31998632 31999200 568 4557
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 32018548 32019135 587 0
H3ac HepG2E 32003160 32004961 1801 0
P300 T30-glioblastomaGSE21026 32015756 32016426 670 0
hScc1 BcellGSE12603 32009455 32009703 248 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
22437 mRNA C2 chr6 32003458 32010812 159 EST chr6 32010229 32017480Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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