AutismKB 2.0

Annotation Detail for TPO


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TPO ( MSA,TDH2A,TPX )
Gene Full Name: thyroid peroxidase
Band: 2p25.3
Quick LinksEntrez ID:7173; OMIM: 606765; Uniprot ID:PERT_HUMAN; ENSEMBL ID: ENSG00000115705; HGNC ID: 12015
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
129N-linked (GlcNAc...) (Potential).
307N-linked (GlcNAc...) (Potential).
342N-linked (GlcNAc...) (Potential).
569N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
129N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
307N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
342N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
569N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
40Phosphoserine(CK2)HMM predict
41Phosphoserine(CK1)HMM predict
129N-linkedHMM predict
186Phosphoserine(ATM)HMM predict
189MethylarginineHMM predict
226Phosphotyrosine(Syk)HMM predict
244Phosphothreonine(MAPK)HMM predict
248O-linkedHMM predict
307N-linkedHMM predict
312N-linkedHMM predict
342N-linkedHMM predict
434Phosphotyrosine(EGFR)HMM predict
466SulfotyrosineHMM predict
473Phosphotyrosine(Syk)HMM predict
478N-linkedHMM predict
482O-linkedHMM predict
482O-linkedHMM predict
483N-linkedHMM predict
569N-linkedHMM predict
690Phosphoserine(CK1)HMM predict
723Phosphoserine(CK1)HMM predict
723Phosphoserine(IKK)HMM predict
867O-linkedHMM predict
881Phosphothreonine(PKA)HMM predict
891Phosphothreonine(CDK)HMM predict
905Phosphoserine(CDC2)HMM predict
914Phosphoserine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000547
  • Location:chr2 1396241-1525501
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1378803 1379246 443 17217
CTCF G2GSE9613 1381487 1381883 396 14557
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1528860 1529060 200 3459
CTCF CD4GSE12889 1533512 1533792 280 8151
CTCF CD4SISSRdata 1528860 1529060 200 3459
CTCF CD4SISSRdata 1533512 1533792 280 8151
CTCF HelaGSE12889 1533609 1533917 308 8262
CTCF G2GSE9613 1526940 1527211 271 1574
CTCF G2GSE9613 1528358 1529033 675 3194
CTCF G2GSE9613 1529391 1529756 365 4072
CTCF G2GSE9613 1532811 1534264 1453 8036
CTCF G2GSE9613 1545210 1545351 141 19779
ER Breast-CancerGSE22609 1539224 1540076 852 14149
GABP k562GSE8489 1537570 1539305 1735 12936
Rb SenescentGSE19898 1528819 1529205 386 3511
TAF k562GSE8489 1537989 1539052 1063 13019
hScc1 G2GSE9613 1528285 1530049 1764 3666
hScc1 G2GSE9613 1533056 1534506 1450 8280
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1397812 1398158 346 0
CTCF G2GSE9613 1400023 1400756 733 0
CTCF G2GSE9613 1410987 1411201 214 0
CTCF G2GSE9613 1419838 1420698 860 0
CTCF G2GSE9613 1428145 1428305 160 0
CTCF G2GSE9613 1430786 1431431 645 0
CTCF G2GSE9613 1443839 1445150 1311 0
CTCF G2GSE9613 1458603 1458740 137 0
CTCF G2GSE9613 1460048 1460719 671 0
CTCF G2GSE9613 1461358 1461744 386 0
CTCF G2GSE9613 1470584 1470937 353 0
CTCF G2GSE9613 1471632 1471890 258 0
CTCF G2GSE9613 1472583 1472984 401 0
CTCF G2GSE9613 1474585 1474902 317 0
CTCF G2GSE9613 1476284 1476458 174 0
CTCF G2GSE9613 1480272 1480529 257 0
CTCF G2GSE9613 1495791 1496188 397 0
CTCF G2GSE9613 1497839 1498386 547 0
CTCF G2GSE9613 1498876 1499497 621 0
CTCF G2GSE9613 1504326 1505023 697 0
CTCF G2GSE9613 1507272 1507658 386 0
CTCF G2GSE9613 1508356 1508864 508 0
CTCF G2GSE9613 1510377 1510849 472 0
CTCF G2GSE9613 1516115 1516223 108 0
CTCF G2GSE9613 1517196 1517534 338 0
CTCF G2GSE9613 1522145 1522459 314 0
HIF1 HypoHepG2 1506110 1508059 1949 0
HIF1 HypoHepG2 1509491 1510722 1231 0
HIF1 HypoHepG2 1513153 1515206 2053 0
Nanog hESGSE18292 1412756 1413004 248 0
STAT1 IFNSISSRdata 1491959 1493383 1424 0
TAF HelaGSE8489 1452894 1453230 336 0
TAF k562GSE8489 1472699 1473266 567 0
TFAP2C MCF7GSE21234 1478650 1479521 871 0
hScc1 BcellGSE12603 1399926 1400756 830 0
hScc1 BcellGSE12603 1419838 1420530 692 0
hScc1 BcellGSE12603 1458603 1458978 375 0
hScc1 BcellGSE12603 1467365 1467654 289 0
hScc1 BcellGSE12603 1471664 1471890 226 0
hScc1 BcellGSE12603 1474723 1474902 179 0
hScc1 BcellGSE12603 1487119 1487694 575 0
hScc1 BcellGSE12603 1504579 1505405 826 0
hScc1 BcellGSE12603 1507080 1507921 841 0
hScc1 BcellGSE12603 1508356 1509390 1034 0
hScc1 BcellGSE12603 1513857 1514322 465 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved