AutismKB 2.0

Annotation Detail for TPP2


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Basic Information Top
Gene Symbol:TPP2 ( FLJ40359,TPP-2 )
Gene Full Name: tripeptidyl peptidase II
Band: 13q33.1
Quick LinksEntrez ID:7174; OMIM: 190470; Uniprot ID:TPP2_HUMAN; ENSEMBL ID: ENSG00000134900; HGNC ID: 12016
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
708N6-acetyllysine.
Location(AA) Modifications Resource
2N-acetylalanine.Swiss-Prot 53.0
Location(AA) Modification Resource
21Phosphothreonine(PKA)HMM predict
105N-linkedHMM predict
161N-linkedHMM predict
167N-linkedHMM predict
176Phosphoserine(ATM)HMM predict
379O-linkedHMM predict
386Phosphotyrosine(INSR)HMM predict
436N-linkedHMM predict
446N-linkedHMM predict
576N-linkedHMM predict
640N-linkedHMM predict
679O-linkedHMM predict
701Phosphotyrosine(Jak)HMM predict
701Phosphotyrosine(EGFR)HMM predict
733S-palmitoylHMM predict
850Phosphoserine(CK2)HMM predict
915Phosphoserine(PKA)HMM predict
937Phosphoserine(PKA)HMM predict
938N-linkedHMM predict
976Phosphoserine(CK1)HMM predict
1002N-linkedHMM predict
1042Phosphotyrosine(Syk)HMM predict
1042SulfotyrosineHMM predict
1147Phosphothreonine(CK2)HMM predict
1158Phosphoserine(ATM)HMM predict
1247CysteineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003291
  • Location:chr13 102047373-102129521
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 102030989 102031306 317 16226
CTCF CD4GSE12889 102042319 102042590 271 4919
CTCF CD4SISSRdata 102030989 102031306 317 16226
CTCF CD4SISSRdata 102042319 102042590 271 4919
CTCF G2GSE9613 102030783 102031208 425 16378
CTCF G2GSE9613 102031747 102032040 293 15480
CTCF G2GSE9613 102039718 102039980 262 7525
CTCF G2GSE9613 102042185 102042560 375 5001
CTCF G2GSE9613 102046672 102047817 1145 129
ER E2-MCF7GSE14664 102046707 102046797 90 622
ER E2-MCF7GSE14664 102046914 102046995 81 419
Fos K562GSE19551 102046927 102047528 601 146
H3ac HepG2E 102046405 102046909 504 717
PHF8 293TGSE20725 102042417 102042811 394 4760
PHF8 293TGSE20725 102046610 102047672 1062 233
PHF8 HeLaGSE20725 102046284 102048035 1751 214
PHF8 Hs68plusFBSGSE20725 102046231 102047953 1722 282
TAF HelaGSE8489 102046405 102046740 335 801
TAF k562GSE8489 102046405 102046827 422 758
USF2 HepG2E 102042095 102042560 465 5046
hScc1 BcellGSE12603 102030819 102031208 389 16360
hScc1 BcellGSE12603 102042378 102042560 182 4905
hScc1 CdLSGSE12603 102030783 102031208 425 16378
hScc1 CdLSGSE12603 102042165 102042560 395 5011
hScc1 G2GSE9613 102030783 102031280 497 16342
hScc1 G2GSE9613 102039718 102039980 262 7525
hScc1 G2GSE9613 102042185 102042560 375 5001
hScc1 G2GSE9613 102046672 102047817 1145 129
p130 SenescentGSE19898 102046560 102047647 1087 270
p130 shRbQuiescentGSE19898 102042378 102042925 547 4722
p130 shRbQuiescentGSE19898 102046340 102047499 1159 454
p130 shRbSenescentGSE19898 102046838 102047400 562 255
p63 keratinocytesGSE17611 102036778 102037684 906 10143
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 HelaGSE14283 102129945 102129976 31 439
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FoxA1 MCF7MACSdata 102105254 102105457 203 0
H3K4me3 colorectalcancer 102048001 102048775 774 0
H3ac HepG2E 102048001 102049071 1070 0
Oct1 HelaGSE14283 102064104 102064133 29 0
Oct1 HelaGSE14283 102070379 102070413 34 0
Oct1 HelaGSE14283 102073712 102073787 75 0
Oct1 HelaGSE14283 102091462 102091496 34 0
Oct1 HelaGSE14283 102107226 102107270 44 0
TAF k562GSE8489 102048070 102049274 1204 0
hScc1 BcellGSE12603 102047166 102047793 627 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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