AutismKB 2.0

Annotation Detail for TPR


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Basic Information Top
Gene Symbol:TPR ( - )
Gene Full Name: translocated promoter region (to activated MET oncogene)
Band: 1q31.1
Quick LinksEntrez ID:7175; OMIM: 189940; Uniprot ID:TPR_HUMAN; ENSEMBL ID: ENSG00000047410; HGNC ID: 12017
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
252N6-acetyllysine.
312N6-acetyllysine.
345N6-acetyllysine.
379Phosphoserine.
381Phosphothreonine.
428N6-acetyllysine.
457N6-acetyllysine.
646Phosphoserine.
713N6-acetyllysine.
723N6-acetyllysine.
748N6-acetyllysine.
755N6-acetyllysine.
920Phosphoserine.
1185Phosphoserine.
1677Phosphothreonine.
1725Phosphoserine.
1804Phosphoserine.
2034Phosphoserine.
2037Phosphoserine.
2048Phosphoserine.
2050Phosphoserine.
2073Phosphoserine.
2155Phosphoserine.
Location(AA) Modifications Resource
1185Phosphoserine.Swiss-Prot 53.0
2023Phosphoserine.Swiss-Prot 53.0
2036PhosphoserinePhospho.ELM 6.0
2059Phosphoserine.Swiss-Prot 53.0
2141Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
54Phosphotyrosine(SRC)HMM predict
54Phosphotyrosine(Syk)HMM predict
62Phosphoserine(CK1)HMM predict
64Phosphoserine(ATM)HMM predict
70N-linkedHMM predict
156N-linkedHMM predict
270Phosphoserine(CK2)HMM predict
334Phosphoserine(IKK)HMM predict
444Phosphotyrosine(Syk)HMM predict
522Phosphoserine(CK2)HMM predict
528Phosphoserine(CK1)HMM predict
637Phosphoserine(IKK)HMM predict
641Phosphothreonine(CDC2)HMM predict
641Phosphothreonine(CDK)HMM predict
646Phosphoserine(IKK)HMM predict
648O-linkedHMM predict
648O-linkedHMM predict
648Phosphoserine(ATM)HMM predict
652O-linkedHMM predict
652O-linkedHMM predict
652Phosphoserine(IKK)HMM predict
653O-linkedHMM predict
653O-linkedHMM predict
709Phosphoserine(ATM)HMM predict
799Phosphoserine(PKG)HMM predict
920Phosphoserine(ATM)HMM predict
960Phosphoserine(IKK)HMM predict
1104O-linkedHMM predict
1187Phosphoserine(CK2)HMM predict
1192Phosphoserine(ATM)HMM predict
1386N-linkedHMM predict
1391N-linkedHMM predict
1392N-linkedHMM predict
1408Phosphothreonine(PKC)HMM predict
1445Phosphotyrosine(Syk)HMM predict
1462Phosphoserine(CK2)HMM predict
1472Phosphoserine(ATM)HMM predict
1492Phosphoserine(IKK)HMM predict
1495Phosphoserine(ATM)HMM predict
1505Phosphoserine(CK1)HMM predict
1505Phosphoserine(CK2)HMM predict
1526Phosphoserine(CK1)HMM predict
1547Phosphothreonine(CK2)HMM predict
1611Phosphoserine(PKG)HMM predict
1660O-linkedHMM predict
1672O-linkedHMM predict
1676O-linkedHMM predict
1676O-linkedHMM predict
1677Phosphothreonine(CDK)HMM predict
1679O-linkedHMM predict
1689N-linkedHMM predict
1692Phosphothreonine(MAPK)HMM predict
1708N-linkedHMM predict
1710O-linkedHMM predict
1716O-linkedHMM predict
1725Phosphoserine(ATM)HMM predict
1743Phosphoserine(IKK)HMM predict
1747O-linkedHMM predict
1747Phosphoserine(IKK)HMM predict
1760Phosphoserine(ATM)HMM predict
1804Phosphoserine(CDC2)HMM predict
1812O-linkedHMM predict
1818O-linkedHMM predict
1818O-linkedHMM predict
1820O-linkedHMM predict
1822O-linkedHMM predict
1822O-linkedHMM predict
1822Phosphothreonine(MAPK)HMM predict
1822Phosphothreonine(CDK)HMM predict
1824O-linkedHMM predict
1838Phosphoserine(CK1)HMM predict
1863PhosphothreonineHMM predict
1877Phosphothreonine(CK2)HMM predict
1886Phosphotyrosine(Syk)HMM predict
1903Phosphotyrosine(INSR)HMM predict
1903PhosphotyrosineHMM predict
1903SulfotyrosineHMM predict
1904Phosphothreonine(INSR)HMM predict
1913Phosphoserine(CK1)HMM predict
1913Phosphoserine(IKK)HMM predict
1931O-linkedHMM predict
1931Phosphothreonine(CK2)HMM predict
1948Phosphoserine(CK2)HMM predict
1987Phosphotyrosine(Syk)HMM predict
2020Phosphoserine(ATM)HMM predict
2023Phosphoserine(CK1)HMM predict
2023PhosphoserineHMM predict
2036Phosphoserine(CK1)HMM predict
2036Phosphoserine(ATM)HMM predict
2046Phosphoserine(CK2)HMM predict
2059Phosphoserine(CDC2)HMM predict
2059Phosphoserine(CDK)HMM predict
2094Phosphoserine(PKG)HMM predict
2094PhosphoserineHMM predict
2123Phosphothreonine(MAPK)HMM predict
2149MethylarginineHMM predict
2166Phosphoserine(CK1)HMM predict
2166PhosphoserineHMM predict
2192Phosphoserine(CK1)HMM predict
2200Phosphothreonine(MAPK)HMM predict
2215O-linkedHMM predict
2217Phosphoserine(CK2)HMM predict
2220Phosphoserine(CK2)HMM predict
2224Phosphoserine(ATM)HMM predict
2233O-linkedHMM predict
2236O-linkedHMM predict
2240O-linkedHMM predict
2241N-linkedHMM predict
2271Phosphoserine(CK2)HMM predict
2271Phosphoserine(ATM)HMM predict
2281Phosphoserine(CK2)HMM predict
2288Phosphoserine(CK1)HMM predict
2290O-linkedHMM predict
2290Phosphoserine(ATM)HMM predict
2295O-linkedHMM predict
2296O-linkedHMM predict
2298Phosphoserine(CK1)HMM predict
2298Phosphoserine(IKK)HMM predict
2301O-linkedHMM predict
2302Phosphoserine(CK1)HMM predict
2302Phosphoserine(IKK)HMM predict
2303Phosphoserine(CDK)HMM predict
2304Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003292
  • Location:chr1 184547410-184611079
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 184610671 184611856 1185 184
ETS1 JurkatGSE17954 184610271 184612152 1881 132
PHF8 Hs68minusFBSGSE20725 184610466 184612115 1649 211
hScc1 BcellGSE12603 184610967 184611215 248 12
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 184561107 184561274 167 0
CTCF CD4SISSRdata 184561107 184561274 167 0
ER Fulvestrant-MCF7GSE14664 184551713 184551753 40 0
H3K4me3 colorectalcancer 184609935 184610846 911 0
H3ac HepG2E 184610132 184610777 645 0
Oct1 HelaGSE14283 184551720 184551748 28 0
Oct1 HelaGSE14283 184597667 184597698 31 0
RARA MCF7GSE15244 184610209 184610846 637 0
TAF HelaGSE8489 184610052 184610814 762 0
TAF k562GSE8489 184609709 184610967 1258 0
TFAP2C MCF7GSE21234 184583875 184584312 437 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2067 mRNA PRG4 chr1 182997646 183015343 200 mRNA TPR chr1 183014615 183076114Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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