AutismKB 2.0

Annotation Detail for TPTE


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Basic Information Top
Gene Symbol:TPTE ( CT44,PTEN2 )
Gene Full Name: transmembrane phosphatase with tensin homology
Band: 21p11.2
Quick LinksEntrez ID:7179; OMIM: 604336; Uniprot ID:TPTE_HUMAN; ENSEMBL ID: ENSG00000166157; HGNC ID: 12023
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
20N-linkedHMM predict
22Phosphoserine(CDC2)HMM predict
22Phosphoserine(ATM)HMM predict
25Phosphothreonine(PKC)HMM predict
121Phosphotyrosine(INSR)HMM predict
224Phosphoserine(PKG)HMM predict
231Phosphothreonine(PKA)HMM predict
368Phosphotyrosine(Jak)HMM predict
387Phosphothreonine(CDK)HMM predict
456N-linkedHMM predict
491N-linkedHMM predict
542Phosphothreonine(PKC)HMM predict
542Phosphothreonine(CK2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_199259
  • Location:chr21 9928613-10012790
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct4 hESGSE17917 10012713 10013100 387 116
SRF HelaGSE8489 10025033 10025210 177 12331
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
SRF HelaGSE8489 9952738 9953549 811 0
TFAP2C MCF7GSE21234 9944396 9945117 721 0
hScc1 BcellGSE12603 10011921 10013104 1183 0
hScc1 CdLSGSE12603 10011787 10013277 1490 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018