AutismKB 2.0

Annotation Detail for TRIO


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Basic Information Top
Gene Symbol:TRIO ( ARHGEF23,FLJ42780,tgat )
Gene Full Name: triple functional domain (PTPRF interacting)
Band: 5p15.2
Quick LinksEntrez ID:7204; OMIM: 601893; Uniprot ID:TRIO_HUMAN; ENSEMBL ID: ENSG00000038382; HGNC ID: 12303
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1545Phosphothreonine.
1903Phosphothreonine.
2282Phosphoserine.
2455Phosphoserine.
2459Phosphoserine.
2467Phosphoserine.
Location(AA) Modifications Resource
1486Phosphothreonine.Swiss-Prot 53.0
1486PhosphothreoninePhospho.ELM 6.0
1844Phosphothreonine.Swiss-Prot 53.0
1844PhosphothreoninePhospho.ELM 6.0
2737Phosphotyrosine (FAK)Phospho.ELM 6.0
Location(AA) Modification Resource
93S-palmitoylHMM predict
115Phosphoserine(CDK)HMM predict
164Phosphotyrosine(INSR)HMM predict
167N-linkedHMM predict
240Phosphoserine(CK2)HMM predict
355Phosphotyrosine(INSR)HMM predict
355Phosphotyrosine(Abl)HMM predict
398Phosphotyrosine(INSR)HMM predict
458Phosphothreonine(MAPK)HMM predict
458Phosphothreonine(CDK)HMM predict
464O-linkedHMM predict
464Phosphoserine(IKK)HMM predict
470N-linkedHMM predict
562Phosphotyrosine(INSR)HMM predict
587Phosphotyrosine(SRC)HMM predict
587Phosphotyrosine(Syk)HMM predict
687N-linkedHMM predict
689Phosphothreonine(CDC2)HMM predict
692N-linkedHMM predict
696N-linkedHMM predict
781N-linkedHMM predict
796Phosphotyrosine(INSR)HMM predict
975Phosphotyrosine(Syk)HMM predict
1107O-linkedHMM predict
1133Phosphothreonine(PKC)HMM predict
1169Phosphotyrosine(EGFR)HMM predict
1193Phosphoserine(IKK)HMM predict
1194N-linkedHMM predict
1197Phosphoserine(CK1)HMM predict
1303Phosphotyrosine(EGFR)HMM predict
1423Phosphoserine(ATM)HMM predict
1503Phosphothreonine(CDC2)HMM predict
1503Phosphothreonine(MAPK)HMM predict
1503Phosphothreonine(CDK)HMM predict
1568Phosphoserine(CK1)HMM predict
1568Phosphoserine(ATM)HMM predict
1574Phosphoserine(ATM)HMM predict
1574Phosphoserine(IKK)HMM predict
1654S-palmitoylHMM predict
1679Phosphoserine(CK1)HMM predict
1679Phosphoserine(CK2)HMM predict
1679Phosphoserine(IKK)HMM predict
1686Phosphoserine(ATM)HMM predict
1686Phosphoserine(IKK)HMM predict
1704Phosphoserine(CDK)HMM predict
1720Phosphoserine(CDC2)HMM predict
1726Phosphoserine(PKG)HMM predict
1726PhosphoserineHMM predict
1750Phosphoserine(PKG)HMM predict
1755Phosphoserine(ATM)HMM predict
1765Phosphothreonine(CDC2)HMM predict
1765Phosphothreonine(MAPK)HMM predict
1786Phosphoserine(IKK)HMM predict
1820Phosphoserine(IKK)HMM predict
1826Phosphoserine(ATM)HMM predict
1842O-linkedHMM predict
1844Phosphothreonine(MAPK)HMM predict
1844Phosphothreonine(CDK)HMM predict
1846O-linkedHMM predict
1869Phosphoserine(CK1)HMM predict
1880Phosphoserine(CDC2)HMM predict
1882Phosphoserine(IKK)HMM predict
1884N-linkedHMM predict
1888N-linkedHMM predict
1889Phosphoserine(CK1)HMM predict
1889Phosphoserine(IKK)HMM predict
1892Phosphoserine(CK1)HMM predict
1905Phosphoserine(CK2)HMM predict
1905PhosphoserineHMM predict
1906Phosphoserine(PKG)HMM predict
1906Phosphoserine(CDC2)HMM predict
2063Phosphoserine(CAMK2)HMM predict
2063Phosphoserine(IKK)HMM predict
2066Phosphothreonine(CK2)HMM predict
2124S-palmitoylHMM predict
2196Phosphoserine(CDC2)HMM predict
2198Phosphoserine(IKK)HMM predict
2230N-linkedHMM predict
2243O-linkedHMM predict
2249O-linkedHMM predict
2256O-linkedHMM predict
2262O-linkedHMM predict
2262Phosphoserine(ATM)HMM predict
2274Phosphothreonine(PKC)HMM predict
2275O-linkedHMM predict
2280O-linkedHMM predict
2295O-linkedHMM predict
2296O-linkedHMM predict
2299Phosphoserine(CK2)HMM predict
2300Phosphoserine(ATM)HMM predict
2308Phosphoserine(IKK)HMM predict
2311Phosphoserine(IKK)HMM predict
2312Phosphothreonine(MAPK)HMM predict
2316O-linkedHMM predict
2332O-linkedHMM predict
2343Phosphoserine(CK2)HMM predict
2358Phosphoserine(CDC2)HMM predict
2365N-linkedHMM predict
2367O-linkedHMM predict
2369O-linkedHMM predict
2370Phosphoserine(CDC2)HMM predict
2370Phosphoserine(ATM)HMM predict
2396Phosphoserine(CDC2)HMM predict
2400Phosphoserine(CDC2)HMM predict
2400Phosphoserine(MAPK)HMM predict
2400Phosphoserine(CDK)HMM predict
2418Phosphoserine(CDC2)HMM predict
2429O-linkedHMM predict
2433Phosphoserine(CDC2)HMM predict
2433Phosphoserine(CDK)HMM predict
2440Phosphoserine(IKK)HMM predict
2454Phosphothreonine(MAPK)HMM predict
2468Phosphoserine(IKK)HMM predict
2472Phosphoserine(IKK)HMM predict
2477Phosphoserine(IKK)HMM predict
2484N-linkedHMM predict
2486Phosphoserine(CK1)HMM predict
2486Phosphoserine(CK2)HMM predict
2490Phosphoserine(CK1)HMM predict
2491Phosphoserine(CK1)HMM predict
2492O-linkedHMM predict
2537Phosphothreonine(PKA)HMM predict
2566Phosphothreonine(PKC)HMM predict
2583Phosphoserine(PKG)HMM predict
2600Phosphotyrosine(Jak)HMM predict
2622SulfotyrosineHMM predict
2698Phosphotyrosine(INSR)HMM predict
2759Phosphothreonine(PKC)HMM predict
2802Phosphothreonine(MAPK)HMM predict
2885N-linkedHMM predict
2914Phosphoserine(CK1)HMM predict
3028AsparagineHMM predict
3038ValineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007118
  • Location:chr5 14196828-14562449
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 14195636 14197314 1678 354
TAF HelaGSE8489 14190732 14191424 692 5751
hScc1 BcellGSE12603 14196286 14196649 363 361
hScc1 CdLSGSE12603 14195808 14197460 1652 195
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 14582015 14582478 463 19797
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 14405181 14405511 330 0
CTCF CD4GSE12889 14458491 14458626 135 0
CTCF CD4SISSRdata 14405181 14405511 330 0
CTCF CD4SISSRdata 14458491 14458626 135 0
CTCF JurkatGSE12889 14405240 14405568 328 0
CTCF G2GSE9613 14197761 14198183 422 0
CTCF G2GSE9613 14207337 14207649 312 0
CTCF G2GSE9613 14253101 14253282 181 0
CTCF G2GSE9613 14322103 14322387 284 0
CTCF G2GSE9613 14323067 14323910 843 0
CTCF G2GSE9613 14356567 14356713 146 0
CTCF G2GSE9613 14379095 14379888 793 0
CTCF G2GSE9613 14387814 14388072 258 0
CTCF G2GSE9613 14405093 14405539 446 0
CTCF G2GSE9613 14411080 14411281 201 0
CTCF G2GSE9613 14412617 14412974 357 0
CTCF G2GSE9613 14417272 14418859 1587 0
CTCF G2GSE9613 14439019 14439463 444 0
CTCF G2GSE9613 14451355 14452891 1536 0
CTCF G2GSE9613 14458274 14459812 1538 0
CTCF G2GSE9613 14479688 14479983 295 0
CTCF G2GSE9613 14494035 14494286 251 0
CTCF G2GSE9613 14535634 14535880 246 0
CTCF G2GSE9613 14536454 14537117 663 0
CTCF G2GSE9613 14540515 14541471 956 0
CTCF G2GSE9613 14544142 14544748 606 0
CTCF G2GSE9613 14545713 14545924 211 0
CTCF G2GSE9613 14552001 14552459 458 0
CTCF G2GSE9613 14556427 14557531 1104 0
CTCF G2GSE9613 14557835 14558841 1006 0
ER E2-MCF7GSE14664 14258622 14258716 94 0
ER E2-MCF7GSE14664 14260677 14260710 33 0
ER Fulvestrant-MCF7GSE14664 14305876 14305911 35 0
ERG prostate-cancerGSE14092 14399996 14400374 378 0
FOXA1 MCF7GSE15244 14209844 14210330 486 0
FOXA1 MCF7GSE15244 14309931 14310519 588 0
Fos K562GSE19551 14321189 14321922 733 0
FoxA1 MCF7MACSdata 14309770 14310294 524 0
H3ac HepG2E 14198264 14198870 606 0
KLF4 hESGSE17917 14323627 14323792 165 0
KLF4 hESGSE17917 14510470 14510818 348 0
Myc K562GSE19551 14303053 14303657 604 0
Myc K562GSE19551 14317641 14318208 567 0
Nanog hESGSE18292 14394906 14395268 362 0
Nanog hESGSE18292 14486051 14486485 434 0
Oct1 H2O2-HelaGSE14283 14351290 14351326 36 0
Oct1 H2O2-HelaGSE14283 14464482 14464509 27 0
Oct1 HelaGSE14283 14305875 14305910 35 0
Oct1 HelaGSE14283 14351287 14351326 39 0
Oct1 HelaGSE14283 14408142 14408191 49 0
P300 T30-glioblastomaGSE21026 14217326 14220310 2984 0
P300 T30-glioblastomaGSE21026 14459561 14460237 676 0
Pol2 GM12878GSE19551 14196790 14198692 1902 0
RARA MCF7GSE15244 14209844 14210439 595 0
Rb GrowingGSE19898 14307640 14307830 190 0
Rb shRbQuiescentGSE19898 14373963 14374192 229 0
STAT1 HeLaGSE12782 14207928 14212242 4314 0
STAT1 HeLaGSE12783 14208020 14211327 3307 0
TAF HelaGSE8489 14225965 14226274 309 0
TAF HelaGSE8489 14454606 14455576 970 0
TFAP2C MCF7GSE21234 14209741 14210411 670 0
TFAP2C MCF7GSE21234 14233598 14233976 378 0
TFAP2C MCF7GSE21234 14309836 14310548 712 0
TFAP2C MCF7GSE21234 14542665 14543423 758 0
VDR GM10861-stimGSE22484 14301305 14306629 5324 0
hScc1 BcellGSE12603 14196984 14197431 447 0
hScc1 BcellGSE12603 14265277 14265511 234 0
hScc1 BcellGSE12603 14323139 14323830 691 0
hScc1 BcellGSE12603 14417650 14418165 515 0
hScc1 BcellGSE12603 14545602 14545971 369 0
hScc1 CdLSGSE12603 14262044 14262322 278 0
hScc1 CdLSGSE12603 14323105 14323721 616 0
hScc1 CdLSGSE12603 14417380 14418056 676 0
hScc1 G2GSE9613 14195636 14198449 2813 0
hScc1 G2GSE9613 14322931 14323721 790 0
hScc1 G2GSE9613 14417492 14418204 712 0
p130 SenescentGSE19898 14303256 14303537 281 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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