AutismKB 2.0

Annotation Detail for TRPC4


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Basic Information Top
Gene Symbol:TRPC4 ( HTRP4,MGC119570,MGC119571,MGC119572,MGC119573,TRP4 )
Gene Full Name: transient receptor potential cation channel, subfamily C, member 4
Band: 13q13.3
Quick LinksEntrez ID:7223; OMIM: 603651; Uniprot ID:TRPC4_HUMAN; ENSEMBL ID: ENSG00000133107; HGNC ID: 12336
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
193Phosphoserine.
195Phosphoserine.
959Phosphotyrosine; by FYN.
972Phosphotyrosine; by FYN.
Location(AA) Modifications Resource
193Phosphoserine.Swiss-Prot 53.0
195Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
30Phosphoserine(ATM)HMM predict
45Phosphotyrosine(INSR)HMM predict
51Phosphoserine(PKG)HMM predict
189Phosphoserine(CK1)HMM predict
193Phosphoserine(PKA)HMM predict
241Phosphotyrosine(EGFR)HMM predict
384Phosphoserine(ATM)HMM predict
621N-linkedHMM predict
622N-linkedHMM predict
655Phosphothreonine(MAPK)HMM predict
662Phosphoserine(CDC2)HMM predict
706Phosphotyrosine(Syk)HMM predict
766N-linkedHMM predict
777Phosphoserine(CK1)HMM predict
781Phosphoserine(CK1)HMM predict
783Phosphoserine(CK1)HMM predict
793N-linkedHMM predict
819N-linkedHMM predict
852Phosphoserine(PKG)HMM predict
955Phosphoserine(CK1)HMM predict
955Phosphoserine(CK2)HMM predict
959SulfotyrosineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_016179
  • Location:chr13 37108794-37341934
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37341982 37342903 921 508
H3K27me3 colorectalcancer 37342507 37343570 1063 1104
Oct1 HelaGSE14283 37348464 37348492 28 6544
RARG MCF7GSE15244 37343048 37343293 245 1236
hScc1 BcellGSE12603 37341916 37342690 774 369
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 37102955 37103329 374 5653
hScc1 BcellGSE12603 37093899 37094074 175 14808
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 37130372 37130413 41 0
Oct1 H2O2-HelaGSE14283 37280062 37280094 32 0
Oct1 H2O2-HelaGSE14283 37317493 37317531 38 0
Oct1 HelaGSE14283 37130372 37130411 39 0
Oct1 HelaGSE14283 37280062 37280094 32 0
Oct1 HelaGSE14283 37317493 37317531 38 0
P300 T30-glioblastomaGSE21026 37128462 37129202 740 0
P300 T30-glioblastomaGSE21026 37219155 37219854 699 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018