Annotation Detail for TTK
Basic Information Top
Gene Symbol: | TTK ( CT96,ESK,FLJ38280,MPS1,MPS1L1,PYT ) |
---|---|
Gene Full Name: | TTK protein kinase |
Band: | 6q14.1 |
Quick Links | Entrez ID:7272; OMIM: 604092; Uniprot ID:TTK_HUMAN; ENSEMBL ID: ENSG00000112742; HGNC ID: 12401 |
Relate to Another Database: | SFARIGene; denovo-db |
Location(AA) | Modification | |
---|---|---|
3 | Phosphoserine. | |
7 | Phosphoserine. | |
33 | Phosphothreonine. | |
37 | Phosphoserine. | |
49 | Phosphoserine. | |
80 | Phosphoserine. | |
216 | Phosphoserine. | |
218 | Phosphoserine. | |
281 | Phosphoserine. | |
317 | Phosphoserine. | |
321 | Phosphoserine. | |
393 | Phosphoserine. | |
431 | Phosphoserine. | |
436 | Phosphoserine. | |
453 | Phosphothreonine. | |
455 | Phosphoserine. | |
821 | Phosphoserine. | |
824 | Phosphoserine. |
Location(AA) | Modifications | Resource |
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Location(AA) | Modification | Resource |
---|---|---|
90 | N-linked | HMM predict |
115 | Sulfotyrosine | HMM predict |
198 | Phosphoserine(IKK) | HMM predict |
200 | Phosphoserine(CK1) | HMM predict |
210 | N-linked | HMM predict |
211 | N-linked | HMM predict |
219 | Phosphothreonine(PKC) | HMM predict |
247 | N-linked | HMM predict |
285 | Phosphothreonine(PKA) | HMM predict |
285 | Phosphothreonine(PKC) | HMM predict |
286 | Phosphoserine(PKC) | HMM predict |
329 | Phosphoserine(CK1) | HMM predict |
342 | N-linked | HMM predict |
358 | Phosphotyrosine(INSR) | HMM predict |
358 | Phosphotyrosine(SRC) | HMM predict |
358 | Phosphotyrosine(EGFR) | HMM predict |
358 | Phosphotyrosine(Syk) | HMM predict |
417 | Phosphoserine(CDK) | HMM predict |
433 | Phosphoserine(IKK) | HMM predict |
446 | Phosphotyrosine(INSR) | HMM predict |
452 | Phosphothreonine(CDC2) | HMM predict |
469 | Phosphotyrosine(Abl) | HMM predict |
546 | N-linked | HMM predict |
583 | Sulfotyrosine | HMM predict |
583 | Phosphotyrosine(Syk) | HMM predict |
583 | Phosphotyrosine(INSR) | HMM predict |
673 | Phosphotyrosine(INSR) | HMM predict |
765 | Phosphoserine(PKG) | HMM predict |
827 | N-linked | HMM predict |
828 | Phosphoserine(CDK) | HMM predict |
829 | Phosphoserine(CDC2) | HMM predict |
- RefSeq ID: NM_003318
- Location:chr6 80771077-80808955
- strand:+
Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
---|---|---|---|---|---|---|
Fos | K562 | GSE19551 | 80770669 | 80771364 | 695 | 61 |
H3K4me3 | colorectal | cancer | 80769990 | 80770693 | 703 | 736 |
H3ac | HepG2 | E | 80769847 | 80770693 | 846 | 808 |
Oct1 | H2O2-Hela | GSE14283 | 80753600 | 80753629 | 29 | 17463 |
PHF8 | Hs68plusFBS | GSE20725 | 80770264 | 80771766 | 1502 | 63 |
TAF | k562 | GSE8489 | 80769368 | 80770436 | 1068 | 1176 |
TFAP2C | MCF7 | GSE21234 | 80770234 | 80771121 | 887 | 400 |
p130 | shRbQuiescent | GSE19898 | 80770429 | 80771653 | 1224 | 37 |
No data |
Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
---|---|---|---|---|---|---|
E2F4 | G0 | GSE7516 | 80770811 | 80771742 | 931 | 0 |
E2F4 | S | GSE7516 | 80770849 | 80771596 | 747 | 0 |
LIN54 | G0 | GSE7516 | 80770849 | 80771669 | 820 | 0 |
LIN9 | G0 | GSE7516 | 80770388 | 80772032 | 1644 | 0 |
LIN9 | S | GSE7516 | 80770693 | 80772180 | 1487 | 0 |
TAF | k562 | GSE8489 | 80771407 | 80772584 | 1177 | 0 |
p130 | Quiescent | GSE19898 | 80770921 | 80771663 | 742 | 0 |
p130 | Senescent | GSE19898 | 80770540 | 80771711 | 1171 | 0 |
p130 | shRbSenescent | GSE19898 | 80770423 | 80771756 | 1333 | 0 |
p130 | G0 | GSE7516 | 80770307 | 80772000 | 1693 | 0 |
p130 | S | GSE7516 | 80770620 | 80771779 | 1159 | 0 |
Micro RNA Name | Stem Loop Name | The chromosome that miRNA located | Publication |
---|---|---|---|
hsa-miR-376a | hsa-mir-376a-1 | 0 | 17322061 |
hsa-miR-376a | hsa-mir-376a-2 | 0 | 17322061 |
hsa-miR-376a* | hsa-mir-376a-1 | 0 | 17322061 |
hsa-miR-376b | hsa-mir-376b | 0 | 17322061 |
hsa-miR-376c | hsa-mir-376c | 0 | 17322061 |
ID in Tarbase | Data Type | Support Type | miRNA | Gene | Direct Support | Publication |
---|---|---|---|---|---|---|
695 | mRNA repression | TRUE | miR-376a-5p | TTK | in vitro reporter gene assay (Luciferase) | 17322061 |
Ensembl | Protein Type | Differentially expressed in | Pathology or Event | Mis Regulation | Gene Expression | Tumour Involvement |
ENSG00000112742 | n_a | n_a | n_a | "lymphocyte, muscle cell" | "malignant tumour, carcinoma, leukaemia, sarcoma" |