AutismKB 2.0

Annotation Detail for UBE2E2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UBE2E2 ( FLJ25157,UBCH8 )
Gene Full Name: ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
Band: 3p24.3
Quick LinksEntrez ID:7325; OMIM: 602163; Uniprot ID:UB2E2_HUMAN; ENSEMBL ID: ENSG00000182247; HGNC ID: 12478
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
19Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
11Phosphoserine(IKK)HMM predict
13Phosphoserine(CK1)HMM predict
15Phosphoserine(ATM)HMM predict
19Phosphoserine(CK2)HMM predict
46Phosphoserine(PKG)HMM predict
55Phosphothreonine(PKC)HMM predict
85Phosphotyrosine(Syk)HMM predict
111Phosphoserine(CDC2)HMM predict
114SulfotyrosineHMM predict
146N-linkedHMM predict
148Phosphoserine(IKK)HMM predict
152Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_152653
  • Location:chr3 23219811-23607073
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K27me3 colorectalcancer 23217212 23218594 1382 1909
KLF4 hESGSE17917 23219411 23219603 192 305
PHF8 HeLaGSE20725 23218955 23220571 1616 49
Rb GrowingGSE19898 23219029 23219178 149 708
hScc1 CdLSGSE12603 23200438 23200705 267 19240
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
FOXA1 MCF7GSE15244 23616306 23617238 932 9699
P300 T30-glioblastomaGSE21026 23616658 23617276 618 9894
PAX3-FKHR Rh4GSE19063 23606598 23608250 1652 351
hScc1 BcellGSE12603 23607419 23607715 296 494
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23219752 23219924 172 0
CTCF G2GSE9613 23337795 23338014 219 0
FOXA1 MCF7GSE15244 23235680 23235967 287 0
FOXA1 MCF7GSE15244 23337795 23338014 219 0
FOXA1 MCF7GSE15244 23593136 23593339 203 0
FoxA1 MCF7MACSdata 23337428 23337986 558 0
FoxA1 MCF7MACSdata 23405554 23405810 256 0
NRSF JurkatGSE13047 23304805 23305100 295 0
NRSF mAbJurkat 23305860 23306103 243 0
NRSF-mono JurkatQuESTdata 23304819 23305099 280 0
Nanog ESGSE20650 23588915 23589298 383 0
Oct1 H2O2-HelaGSE14283 23466365 23466403 38 0
Oct1 HelaGSE14283 23302541 23302569 28 0
Oct1 HelaGSE14283 23466365 23466403 38 0
P300 T30-glioblastomaGSE21026 23596674 23597252 578 0
Rb shRbQuiescentGSE19898 23220274 23220451 177 0
Rb shRbSenescenceGSE19898 23341376 23341541 165 0
STAT1 HeLaGSE12782 23534461 23535816 1355 0
STAT1 HeLaGSE12783 23534547 23535816 1269 0
Sox2 hESGSE18292 23497737 23498285 548 0
TFAP2C MCF7GSE21234 23337296 23337724 428 0
TFAP2C MCF7GSE21234 23405511 23406014 503 0
USF1 HepG2E 23376951 23377275 324 0
hScc1 BcellGSE12603 23219752 23220413 661 0
hScc1 CdLSGSE12603 23219752 23220645 893 0
hScc1 CdLSGSE12603 23567986 23568276 290 0
p63 keratinocytesGSE17611 23565396 23566264 868 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018