AutismKB 2.0

Annotation Detail for UBE2H


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Basic Information Top
Gene Symbol:UBE2H ( E2-20K,UBC8,UBCH,UBCH2 )
Gene Full Name: ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
Band: 7q32.2
Quick LinksEntrez ID:7328; OMIM: 601082; Uniprot ID:UBE2H_HUMAN; ENSEMBL ID: ENSG00000186591; HGNC ID: 12484
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
60N6-acetyllysine.
64N6-acetyllysine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
5Phosphoserine(CDC2)HMM predict
5Phosphoserine(CDK)HMM predict
13Phosphothreonine(PKA)HMM predict
64MethyllysineHMM predict
65Phosphoserine(CDC2)HMM predict
92N-linkedHMM predict
150Phosphothreonine(PKC)HMM predict
166O-linkedHMM predict
166Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003344
  • Location:chr7 129260230-129380024
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 129385335 129387100 1765 6193
CBP T30-glioblastomaGSE21026 129396643 129397736 1093 17165
ETS1 JurkatGSE17954 129379787 129380649 862 194
FOXA1 MCF7GSE15244 129396912 129397422 510 17143
Fos K562GSE19551 129385456 129387244 1788 6326
FoxA1 MCF7MACSdata 129396854 129397119 265 16962
Gata2 K562GSE18868 129385445 129386453 1008 5925
Myc K562GSE19551 129396815 129397268 453 17017
Oct1 HelaGSE14283 129389837 129389872 35 9830
P300 T0-glioblastomaGSE21026 129396551 129397531 980 17017
P300 T30-glioblastomaGSE21026 129385384 129386425 1041 5880
P300 T30-glioblastomaGSE21026 129396671 129397741 1070 17182
TFAP2C MCF7GSE21234 129385630 129386156 526 5869
TFAP2C MCF7GSE21234 129396738 129397428 690 17059
p130 SenescentGSE19898 129397149 129397538 389 17319
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 129252925 129253074 149 7231
CTCF CD4SISSRdata 129252925 129253074 149 7231
CTCF G2GSE9613 129252125 129253433 1308 7452
CTCF G2GSE9613 129256413 129257567 1154 3241
CTCF G2GSE9613 129258953 129259430 477 1039
NRSF pAbJurkat 129252261 129252603 342 7799
Nanog hESGSE18292 129257132 129257581 449 2874
P300 T30-glioblastomaGSE21026 129258246 129259335 1089 1440
Rb GrowingGSE19898 129258548 129258759 211 1577
Rb QuiescentGSE19898 129258437 129258684 247 1670
Rb QuiescentGSE19898 129258726 129258902 176 1417
Rb SenescentGSE19898 129252446 129253039 593 7488
Rb SenescentGSE19898 129258484 129258798 314 1590
Rb shRbSenescenceGSE19898 129252753 129252967 214 7371
Sox2 hESGSE18292 129257143 129257365 222 2977
TFAP2C MCF7GSE21234 129251825 129253001 1176 7818
hScc1 BcellGSE12603 129252125 129253198 1073 7569
hScc1 BcellGSE12603 129255468 129255685 217 4654
hScc1 BcellGSE12603 129256947 129257429 482 3043
hScc1 CdLSGSE12603 129252125 129253198 1073 7569
hScc1 CdLSGSE12603 129256636 129257462 826 3182
hScc1 G2GSE9613 129252125 129253433 1308 7452
hScc1 G2GSE9613 129256947 129257503 556 3006
p130 QuiescentGSE19898 129252668 129252967 299 7413
p130 SenescentGSE19898 129252448 129252879 431 7567
p130 SenescentGSE19898 129258517 129258869 352 1538
p130 shRbQuiescentGSE19898 129258073 129258565 492 1912
p130 shRbSenescentGSE19898 129252871 129253046 175 7272
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 129260976 129261217 241 0
CTCF G2GSE9613 129379151 129379908 757 0
ER Fulvestrant-MCF7GSE14664 129343264 129343343 79 0
ER Fulvestrant-MCF7GSE14664 129343385 129343427 42 0
ER Fulvestrant-MCF7GSE14664 129371028 129371073 45 0
ER Fulvestrant-MCF7GSE14664 129377585 129377622 37 0
FOXA1 MCF7GSE15244 129375823 129376901 1078 0
FoxA1 MCF7MACSdata 129376150 129376427 277 0
H3K4me2 HCT116GSE10453 129377501 129378942 1441 0
H3K4me3 colorectalcancer 129377501 129379465 1964 0
H3ac HepG2E 129376270 129379575 3305 0
Nanog hESGSE18292 129278877 129279328 451 0
Oct1 H2O2-HelaGSE14283 129371030 129371059 29 0
Oct1 HelaGSE14283 129270615 129270673 58 0
Oct1 HelaGSE14283 129371022 129371070 48 0
Oct1 HelaGSE14283 129372317 129372344 27 0
Oct1 HelaGSE14283 129377573 129377616 43 0
RARA MCF7GSE15244 129375754 129376932 1178 0
RNAII Tamoxifen-MCF7GSE14664 129371024 129371070 46 0
STAT1 HeLaGSE12783 129280127 129281745 1618 0
TAF HelaGSE8489 129296560 129297109 549 0
TAF HelaGSE8489 129360736 129361089 353 0
TAF HelaGSE8489 129372372 129372669 297 0
TAF HelaGSE8489 129377027 129378305 1278 0
TFAP2C MCF7GSE21234 129280713 129281285 572 0
TFAP2C MCF7GSE21234 129375888 129376977 1089 0
TFAP2C MCF7GSE21234 129379157 129379665 508 0
hScc1 G2GSE9613 129379151 129379949 798 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018