AutismKB 2.0

Annotation Detail for UBE2N


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UBE2N ( MGC131857,MGC8489,UBC13,UbcH-ben )
Gene Full Name: ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
Band: 12q22
Quick LinksEntrez ID:7334; OMIM: 603679; Uniprot ID:UBE2N_HUMAN; ENSEMBL ID: ENSG00000177889; HGNC ID: 12492
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
10N6-acetyllysine.
82N6-acetyllysine.
94N6-acetyllysine.
Location(AA) Modifications Resource
92Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in ISG15).Swiss-Prot 53.0
Location(AA) Modification Resource
96Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003348
  • Location:chr12 92326218-92360156
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP HelaGSE8489 92368702 92368991 289 8690
H3K4me2 HCT116GSE10453 92360444 92361041 597 586
H3K4me3 colorectalcancer 92360524 92361188 664 700
H3ac HepG2E 92360407 92361523 1116 809
Oct1 H2O2-HelaGSE14283 92370051 92370080 29 9909
Oct1 HelaGSE14283 92362785 92362816 31 2644
Oct1 HelaGSE14283 92370050 92370078 28 9908
RARG MCF7GSE15244 92360478 92361041 563 603
RNAII Tamoxifen-MCF7GSE14664 92362711 92362805 94 2602
Rb SenescentGSE19898 92359896 92360448 552 16
TAF HelaGSE8489 92360407 92361598 1191 846
TAF k562GSE8489 92360190 92361227 1037 552
VDR GM10861-stimGSE22484 92366571 92367887 1316 7073
p130 QuiescentGSE19898 92360117 92360346 229 75
p130 SenescentGSE19898 92359962 92360681 719 165
p130 shRbQuiescentGSE19898 92359879 92360717 838 142
p130 shRbSenescentGSE19898 92359969 92360864 895 260
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 92337305 92337642 337 0
CTCF CD4SISSRdata 92337305 92337642 337 0
CTCF G2GSE9613 92359043 92360190 1147 0
ETS1 JurkatGSE17954 92359035 92360553 1518 0
GABP k562GSE8489 92357414 92359205 1791 0
H3K4me2 HCT116GSE10453 92358011 92358830 819 0
H3K4me3 colorectalcancer 92358336 92359169 833 0
H3ac HepG2E 92357414 92359141 1727 0
PHF8 HeLaGSE20725 92358899 92360710 1811 0
RARA MCF7GSE15244 92326698 92327202 504 0
RARA MCF7GSE15244 92346333 92346835 502 0
RARG MCF7GSE15244 92332379 92332513 134 0
TAF HelaGSE8489 92357414 92359253 1839 0
TAF k562GSE8489 92357414 92359141 1727 0
hScc1 BcellGSE12603 92358966 92360190 1224 0
hScc1 CdLSGSE12603 92337357 92337858 501 0
hScc1 CdLSGSE12603 92359008 92360190 1182 0
hScc1 G2GSE9613 92359008 92360444 1436 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-125a-3p hsa-mir-125a 19 20542030
hsa-miR-125a-5p hsa-mir-125a 19 20542030
hsa-miR-125b hsa-mir-125b-1 11 20542030
hsa-miR-125b hsa-mir-125b-2 21 20542030
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved