AutismKB 2.0

Annotation Detail for UTRN


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Basic Information Top
Gene Symbol:UTRN ( DMDL,DRP,DRP1,FLJ23678 )
Gene Full Name: utrophin
Band: 6q24.2
Quick LinksEntrez ID:7402; OMIM: 128240; Uniprot ID:UTRO_HUMAN; ENSEMBL ID: ENSG00000152818; HGNC ID: 12635
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
4Phosphotyrosine.
10Phosphoserine.
295Phosphoserine.
1266Phosphothreonine.
3180Phosphoserine.
3182Phosphoserine.
3297Phosphoserine.
3304Phosphoserine.
Location(AA) Modifications Resource
295Phosphoserine.Swiss-Prot 53.0
295PhosphoserinePhospho.ELM 6.0
825PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
85Phosphothreonine(PKC)HMM predict
145Phosphoserine(CK1)HMM predict
163Phosphothreonine(PKC)HMM predict
167Phosphotyrosine(SRC)HMM predict
168Phosphoserine(IKK)HMM predict
174N-linkedHMM predict
268Phosphothreonine(PKC)HMM predict
295Phosphoserine(ATM)HMM predict
295PhosphoserineHMM predict
300Phosphothreonine(MAPK)HMM predict
339Phosphoserine(CK2)HMM predict
339Phosphoserine(ATM)HMM predict
365Phosphoserine(PKA)HMM predict
383Phosphoserine(CK2)HMM predict
383Phosphoserine(ATM)HMM predict
491Phosphoserine(CK1)HMM predict
491Phosphoserine(CK2)HMM predict
546Phosphothreonine(PKC)HMM predict
557Phosphothreonine(PKC)HMM predict
586Phosphothreonine(PKA)HMM predict
586Phosphothreonine(PKC)HMM predict
612Phosphoserine(CK2)HMM predict
712Phosphothreonine(PKC)HMM predict
718Phosphotyrosine(INSR)HMM predict
718Phosphotyrosine(Syk)HMM predict
749N-linkedHMM predict
782N-linkedHMM predict
833Phosphoserine(CK1)HMM predict
833Phosphoserine(IKK)HMM predict
836Phosphoserine(CK1)HMM predict
867Phosphoserine(ATM)HMM predict
952Phosphothreonine(PKC)HMM predict
952Phosphothreonine(CK2)HMM predict
1115Phosphothreonine(PKC)HMM predict
1121Phosphoserine(CK1)HMM predict
1121Phosphoserine(CK2)HMM predict
1123Phosphoserine(ATM)HMM predict
1148Phosphotyrosine(Syk)HMM predict
1155Phosphotyrosine(EGFR)HMM predict
1204Phosphothreonine(CK2)HMM predict
1205Phosphoserine(CK1)HMM predict
1259Phosphothreonine(PKA)HMM predict
1278Phosphoserine(CK1)HMM predict
1286N-linkedHMM predict
1400Phosphoserine(ATM)HMM predict
1405Phosphoserine(CDC2)HMM predict
1405Phosphoserine(MAPK)HMM predict
1498Phosphothreonine(PKC)HMM predict
1555Phosphoserine(CK1)HMM predict
1572Phosphothreonine(CK2)HMM predict
1683Phosphothreonine(PKC)HMM predict
1757Phosphotyrosine(EGFR)HMM predict
1795Phosphoserine(CK2)HMM predict
1796Phosphoserine(CK1)HMM predict
1796Phosphoserine(CK2)HMM predict
1796Phosphoserine(CK2)HMM predict
1796Phosphoserine(ATM)HMM predict
1796PhosphoserineHMM predict
1900Phosphotyrosine(EGFR)HMM predict
1900SulfotyrosineHMM predict
2036N-linkedHMM predict
2112Phosphothreonine(PKA)HMM predict
2140N-linkedHMM predict
2153Phosphoserine(PKA)HMM predict
2153Phosphoserine(CK1)HMM predict
2168N-linkedHMM predict
2172N-linkedHMM predict
2191Phosphoserine(ATM)HMM predict
2191Phosphoserine(IKK)HMM predict
2223Phosphoserine(CAMK2)HMM predict
2223Phosphoserine(CK1)HMM predict
2263N-linkedHMM predict
2285SulfotyrosineHMM predict
2407Phosphoserine(CK2)HMM predict
2419Phosphotyrosine(Jak)HMM predict
2419Phosphotyrosine(Syk)HMM predict
2444Phosphothreonine(PKC)HMM predict
2614Phosphotyrosine(INSR)HMM predict
2614Phosphotyrosine(SRC)HMM predict
2614Phosphotyrosine(Jak)HMM predict
2615Phosphoserine(CK1)HMM predict
2649Phosphothreonine(MAPK)HMM predict
2665Phosphoserine(PKG)HMM predict
3100Phosphoserine(CDK)HMM predict
3180Phosphoserine(ATM)HMM predict
3208N-linkedHMM predict
3217Phosphoserine(CK1)HMM predict
3217Phosphoserine(IKK)HMM predict
3243O-linkedHMM predict
3243O-linkedHMM predict
3243Phosphoserine(ATM)HMM predict
3243Phosphoserine(IKK)HMM predict
3247Phosphoserine(CDC2)HMM predict
3247Phosphoserine(IKK)HMM predict
3304Phosphoserine(ATM)HMM predict
3309Phosphoserine(CK2)HMM predict
3370Phosphoserine(CDK)HMM predict
3417SerineHMM predict
3421Phosphoserine(IKK)HMM predict
3422CysteineHMM predict
3425AsparagineHMM predict
3426ValineHMM predict
3427ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_007124
  • Location:chr6 144654565-145215860
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 144647477 144648649 1172 6503
ER E2-MCF7GSE14664 144642031 144642065 34 12518
FOXA1 MCF7GSE15244 144649388 144650340 952 4702
FoxA1 MCF7MACSdata 144646540 144646850 310 7871
FoxA1 MCF7MACSdata 144650001 144650329 328 4401
GABP k562GSE8489 144651930 144652250 320 2476
H3K4me3 colorectalcancer 144649570 144650164 594 4699
H3ac HepG2E 144648227 144649026 799 5939
H3ac HepG2E 144649323 144651009 1686 4400
Myc hESGSE17917 144647821 144648095 274 6608
Oct1 HelaGSE14283 144642034 144642094 60 12502
Oct1 HelaGSE14283 144643372 144643400 28 11180
PHF8 HeLaGSE20725 144647432 144650204 2772 5748
TAF k562GSE8489 144651930 144652250 320 2476
TFAP2C MCF7GSE21234 144641333 144641961 628 12919
TFAP2C MCF7GSE21234 144649881 144650310 429 4470
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 144707417 144707542 125 0
CTCF CD4GSE12889 144844996 144845238 242 0
CTCF CD4SISSRdata 144707417 144707542 125 0
CTCF CD4SISSRdata 144844996 144845238 242 0
CTCF G2GSE9613 144669104 144669318 214 0
CTCF G2GSE9613 144698982 144699276 294 0
CTCF G2GSE9613 144701389 144701570 181 0
CTCF G2GSE9613 144844877 144845286 409 0
CTCF G2GSE9613 144944772 144945009 237 0
CTCF G2GSE9613 145141948 145142173 225 0
ER E2-MCF7GSE14664 144920012 144920049 37 0
ER Fulvestrant-MCF7GSE14664 144920016 144920049 33 0
FOXA1 MCF7GSE15244 144684907 144685457 550 0
FOXA1 MCF7GSE15244 144738233 144738766 533 0
Fos K562GSE19551 144905861 144906614 753 0
Fos K562GSE19551 144956182 144956428 246 0
FoxA1 MCF7MACSdata 144777954 144778152 198 0
FoxA1 MCF7MACSdata 144923100 144923232 132 0
H3ac HepG2E 144703034 144703280 246 0
H3ac HepG2E 145016957 145017363 406 0
H3ac HepG2E 145022281 145023610 1329 0
KLF4 hESGSE17917 144692607 144692806 199 0
Myc K562GSE19551 144844963 144845191 228 0
Oct1 H2O2-HelaGSE14283 144791224 144791283 59 0
Oct1 H2O2-HelaGSE14283 145088158 145088187 29 0
Oct1 H2O2-HelaGSE14283 145096797 145096854 57 0
Oct1 H2O2-HelaGSE14283 145120260 145120287 27 0
Oct1 HelaGSE14283 144677548 144677579 31 0
Oct1 HelaGSE14283 144906599 144906628 29 0
Oct1 HelaGSE14283 144920017 144920052 35 0
Oct1 HelaGSE14283 144939185 144939214 29 0
Oct1 HelaGSE14283 145047300 145047328 28 0
Oct1 HelaGSE14283 145055997 145056069 72 0
Oct1 HelaGSE14283 145060512 145060583 71 0
Oct1 HelaGSE14283 145065274 145065345 71 0
Oct1 HelaGSE14283 145088157 145088193 36 0
Oct1 HelaGSE14283 145156425 145156456 31 0
Oct4 hESGSE17917 144844979 144845238 259 0
Oct4 hESGSE17917 145009576 145009976 400 0
Oct4 hESGSE21916 144753110 144753403 293 0
Oct4 hESGSE21916 145020479 145021047 568 0
P300 T30-glioblastomaGSE21026 145073054 145073592 538 0
RARA MCF7GSE15244 144693482 144694006 524 0
RARA MCF7GSE15244 145160681 145161504 823 0
RARG MCF7GSE15244 144693517 144694962 1445 0
Rb QuiescentGSE19898 144994001 144994193 192 0
SRF GMOGSE8489 144999447 144999763 316 0
Stat6 IL-4-hr4GSE17850 145088762 145089220 458 0
TAF HelaGSE8489 144667428 144667597 169 0
TAF HelaGSE8489 144727949 144728217 268 0
TAF k562GSE8489 144927900 144929674 1774 0
TFAP2C MCF7GSE21234 144723063 144723693 630 0
TFAP2C MCF7GSE21234 145052417 145052857 440 0
TFAP2C MCF7GSE21234 145073132 145073560 428 0
TFAP2C MCF7GSE21234 145088823 145089352 529 0
USF2 HepG2E 144706108 144706882 774 0
VDR GM10855-stimGSE22484 144951047 144952474 1427 0
hScc1 BcellGSE12603 144844877 144845348 471 0
hScc1 BcellGSE12603 144944477 144945047 570 0
hScc1 BcellGSE12603 145141948 145142173 225 0
hScc1 BcellGSE12603 145198493 145198756 263 0
hScc1 CdLSGSE12603 144844877 144845383 506 0
hScc1 CdLSGSE12603 144944772 144945118 346 0
hScc1 CdLSGSE12603 144948030 144948586 556 0
hScc1 CdLSGSE12603 145141797 145142173 376 0
p130 QuiescentGSE19898 144993995 144994126 131 0
p130 SenescentGSE19898 144779128 144779378 250 0
p63 keratinocytesGSE17611 144735305 144736668 1363 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-181b hsa-mir-181b-1 1 20347265
hsa-miR-181b hsa-mir-181b-2 9 20347265
hsa-miR-198 hsa-mir-198 0 20347265
hsa-miR-206 hsa-mir-206 6 20347265
hsa-miR-206 hsa-mir-206 6 17030984
hsa-miR-24 hsa-mir-24-1 9 20347265
hsa-miR-24 hsa-mir-24-2 19 20347265
hsa-miR-24-1* hsa-mir-24-1 9 20347265
hsa-miR-24-2* hsa-mir-24-2 19 20347265
hsa-miR-26b hsa-mir-26b 2 20347265
hsa-miR-26b* hsa-mir-26b 2 20347265
hsa-miR-30b hsa-mir-30b 8 20347265
hsa-miR-30b* hsa-mir-30b 8 20347265
hsa-miR-30e hsa-mir-30e 1 20347265
hsa-miR-30e* hsa-mir-30e 1 20347265
hsa-miR-92a hsa-mir-92a-1 13 20347265
hsa-miR-92a hsa-mir-92a-2 X 20347265
hsa-miR-92a-1* hsa-mir-92a-1 13 20347265
hsa-miR-92a-2* hsa-mir-92a-2 X 20347265
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
523 mRNA repression TRUE miR-206 UTRN in vitro reporter gene assay (Luciferase) 17030984
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000152818 mesenchymal-epithelial transition (MET) n_a n_a n_a n_a
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
23284 mRNA UTRN chr6 144654657 145209657 93 EST chr6 145203115 145203739Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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