AutismKB 2.0

Annotation Detail for VDAC2


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Basic Information Top
Gene Symbol:VDAC2 ( FLJ23841,POR )
Gene Full Name: voltage-dependent anion channel 2
Band: 10q22.2
Quick LinksEntrez ID:7417; OMIM: 193245; Uniprot ID:VDAC2_HUMAN; ENSEMBL ID: ENSG00000165637; HGNC ID: 12672
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
31N6-acetyllysine.
39N6-acetyllysine.
72N6-acetyllysine.
74N6-acetyllysine.
115Phosphoserine.
206Phosphotyrosine (By similarity).
236Phosphotyrosine (By similarity).
Location(AA) Modifications Resource
46N6-acetyllysine (By similarity).Swiss-Prot 53.0
89N6-acetyllysine (By similarity).Swiss-Prot 53.0
130Phosphoserine.Swiss-Prot 53.0
130PhosphoserinePhospho.ELM 6.0
251Phosphotyrosine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
70Phosphoserine(CK2)HMM predict
75O-linkedHMM predict
77O-linkedHMM predict
128O-linkedHMM predict
221Phosphotyrosine(EGFR)HMM predict
241N-linkedHMM predict
265N-linkedHMM predict
276Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003375
  • Location:chr10 76640568-76661209
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 76639627 76641178 1551 166
FoxA1 MCF7MACSdata 76635948 76636171 223 4509
H3ac HepG2E 76637903 76638243 340 2496
Oct1 HelaGSE14283 76626176 76626203 27 14379
P300 T30-glioblastomaGSE21026 76632425 76633081 656 7816
PHF8 HeLaGSE20725 76639406 76641282 1876 225
Rb QuiescentGSE19898 76640264 76640496 232 189
Rb SenescentGSE19898 76638191 76638367 176 2290
Rb SenescentGSE19898 76640138 76640647 509 176
hScc1 BcellGSE12603 76640130 76640866 736 71
p130 SenescentGSE19898 76632559 76632849 290 7865
p130 SenescentGSE19898 76638046 76638402 356 2345
p130 SenescentGSE19898 76639786 76640373 587 489
p130 shRbSenescentGSE19898 76638122 76638333 211 2341
p130 shRbSenescentGSE19898 76639687 76639880 193 785
p130 shRbSenescentGSE19898 76639904 76640613 709 310
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
USF1 HepG2E 76660405 76662429 2024 208
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 76660351 76660672 321 0
CTCF CD4SISSRdata 76660351 76660672 321 0
H3K4me2 HCT116GSE10453 76641583 76642159 576 0
H3K4me3 colorectalcancer 76641230 76642159 929 0
H3ac HepG2E 76640987 76642159 1172 0
H3ac HepG2E 76646080 76646463 383 0
Rb GrowingGSE19898 76641334 76641535 201 0
TAF HelaGSE8489 76641077 76642120 1043 0
TAF k562GSE8489 76641077 76642159 1082 0
USF2 HepG2E 76660405 76660876 471 0
hScc1 BcellGSE12603 76660441 76660876 435 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018