AutismKB 2.0

Annotation Detail for VIM


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Basic Information Top
Gene Symbol:VIM ( FLJ36605 )
Gene Full Name: vimentin
Band: 10p13
Quick LinksEntrez ID:7431; OMIM: 193060; Uniprot ID:VIME_HUMAN; ENSEMBL ID: ENSG00000026025; HGNC ID: 12692
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylserine.
5Phosphoserine.
7Phosphoserine; by PKA and PKC.
8Phosphoserine.
9Phosphoserine; by PKC.
10Phosphoserine; by PKC.
20Phosphothreonine.
25Phosphoserine; by PKA and PKC (By
26Phosphoserine; by PKC (By similarity).
27Phosphoserine.
29Phosphoserine.
33Phosphothreonine.
34Phosphoserine.
38Phosphotyrosine.
39Phosphoserine; by CaMK2, PKA and PKC.
42Phosphoserine; by PKC.
47Phosphoserine.
49Phosphoserine (By similarity).
51Phosphoserine; by PKA and PKC (By
53Phosphotyrosine.
55Phosphoserine.
56Phosphoserine.
61Phosphotyrosine.
66Phosphoserine; by PKA and PKC (By
72Phosphoserine.
73Phosphoserine.
83Phosphoserine.
104N6-acetyllysine.
117Phosphotyrosine.
120N6-acetyllysine.
139N6-acetyllysine.
144Phosphoserine.
214Phosphoserine.
226Phosphoserine.
261Phosphoserine.
266Phosphothreonine.
292N6-acetyllysine.
299Phosphoserine.
373N6-acetyllysine.
402N6-acetyllysine.
409Phosphoserine.
412Phosphoserine.
419Phosphoserine (By similarity).
420Phosphoserine.
430Phosphoserine.
445N6-acetyllysine.
446Phosphothreonine.
458Phosphothreonine.
459Phosphoserine.
Location(AA) Modifications Resource
2N-acetylserine.Swiss-Prot 53.0
5Phosphoserine.Swiss-Prot 53.0
7Phosphoserine (by PKA and PKC).Swiss-Prot 53.0
8Phosphoserine.Swiss-Prot 53.0
9Phosphoserine (by PKC).Swiss-Prot 53.0
10Phosphoserine (by PKC).Swiss-Prot 53.0
25Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
25Phosphoserine (PAK
26Phosphoserine (by PKC) (By similarity).Swiss-Prot 53.0
26PhosphoserinePhospho.ELM 6.0
27Phosphoserine.Swiss-Prot 53.0
34Phosphoserine (by PKC) (By similarity).Swiss-Prot 53.0
38Phosphoserine (MAPKAPK2;PAK)Phospho.ELM 6.0
39Phosphoserine (by CaMK2, PKA and PKC).Swiss-Prot 53.0
42Phosphoserine (by PKC).Swiss-Prot 53.0
47Phosphoserine (by PKA) (By similarity).Swiss-Prot 53.0
50Phosphoserine (MAPKAPK2;PAK)Phospho.ELM 6.0
51Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
52PhosphotyrosinePhospho.ELM 6.0
55Phosphoserine (MAPKAPK2;CDK)Phospho.ELM 6.0
56Phosphoserine.Swiss-Prot 53.0
60PhosphotyrosinePhospho.ELM 6.0
65Phosphoserine (PAK
66Phosphoserine (by PKA and PKC) (Bysimilarity).Swiss-Prot 53.0
71Phosphoserine (ROCK1;ROCK
72Phosphoserine.Swiss-Prot 53.0
72Phosphoserine (PAK1;PAK
73Phosphoserine.Swiss-Prot 53.0
82Phosphoserine (MAPKAPK2;CaM)Phospho.ELM 6.0
83Phosphoserine (by CaMK2) (By similarity).Swiss-Prot 53.0
117Phosphotyrosine.Swiss-Prot 53.0
213PhosphoserinePhospho.ELM 6.0
214Phosphoserine.Swiss-Prot 53.0
411PhosphoserinePhospho.ELM 6.0
412Phosphoserine.Swiss-Prot 53.0
420Phosphoserine.Swiss-Prot 53.0
425PhosphothreoninePhospho.ELM 6.0
429PhosphoserinePhospho.ELM 6.0
430Phosphoserine.Swiss-Prot 53.0
458Phosphothreonine.Swiss-Prot 53.0
458PhosphoserinePhospho.ELM 6.0
459Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
5Phosphoserine(IKK)HMM predict
7PhosphoserineHMM predict
7Phosphoserine(PKG)HMM predict
9Phosphoserine(CDC2)HMM predict
10Phosphoserine(PKC)HMM predict
22O-linkedHMM predict
25Phosphoserine(CK1)HMM predict
25Phosphoserine(PKA)HMM predict
27O-linkedHMM predict
27O-linkedHMM predict
29Phosphoserine(IKK)HMM predict
32O-linkedHMM predict
35O-linkedHMM predict
39Phosphoserine(CAMK2)HMM predict
39Phosphoserine(PKA)HMM predict
47Phosphoserine(PKA)HMM predict
47O-linkedHMM predict
51Phosphoserine(PKA)HMM predict
56Phosphoserine(CDC2)HMM predict
66Phosphoserine(PKA)HMM predict
72PhosphoserineHMM predict
276Phosphotyrosine(Syk)HMM predict
417N-linkedHMM predict
422N-linkedHMM predict
436Phosphothreonine(CDK)HMM predict
456N-linkedHMM predict
459Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003380
  • Location:chr10 17311303-17319597
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 17298153 17298801 648 12827
Fos K562GSE19551 17309892 17310969 1077 873
H3K27me3 colorectalcancer 17306883 17307028 145 4348
H3K27me3 colorectalcancer 17308965 17310029 1064 1807
LIN9 SGSE7516 17310194 17310603 409 905
Rb QuiescentGSE19898 17310778 17310963 185 433
Rb SenescentGSE19898 17310083 17311445 1362 540
hScc1 BcellGSE12603 17310420 17311709 1289 239
hScc1 CdLSGSE12603 17309283 17311328 2045 998
p130 SenescentGSE19898 17310144 17311290 1146 587
p130 shRbQuiescentGSE19898 17310169 17311046 877 696
p130 shRbSenescentGSE19898 17310159 17310924 765 762
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP HelaGSE8489 17325271 17325579 308 5828
GABP HelaGSE8489 17334076 17334502 426 14692
Myc K562GSE19551 17329311 17329674 363 9895
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Myc hESGSE17917 17311545 17311770 225 0
TFAP2C MCF7GSE21234 17312119 17313042 923 0
hScc1 BcellGSE12603 17312507 17312863 356 0
hScc1 CdLSGSE12603 17312471 17313103 632 0
p130 SenescentGSE19898 17312007 17313400 1393 0
p130 shRbQuiescentGSE19898 17311681 17312006 325 0
p130 shRbQuiescentGSE19898 17312116 17312575 459 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-124 hsa-mir-124-1 8 19843643
hsa-miR-124 hsa-mir-124-2 8 19843643
hsa-miR-124 hsa-mir-124-3 20 19843643
hsa-miR-124* hsa-mir-124-1 8 19843643
hsa-miR-124* hsa-mir-124-2 8 19843643
hsa-miR-124* hsa-mir-124-3 20 19843643
hsa-miR-17 hsa-mir-17 13 19771525
hsa-miR-17* hsa-mir-17 13 19771525
hsa-miR-203 hsa-mir-203 14 19843643
hsa-miR-375 hsa-mir-375 2 19843643
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
2858 mRNA VIM chr10 17311299 17319598 641 EST chr10 17297076 17311990Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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