AutismKB 2.0

Annotation Detail for VRK1


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Basic Information Top
Gene Symbol:VRK1 ( MGC117401,MGC138280,MGC142070,PCH1 )
Gene Full Name: vaccinia related kinase 1
Band: 14q32.2
Quick LinksEntrez ID:7443; OMIM: 602168; Uniprot ID:VRK1_HUMAN; ENSEMBL ID: ENSG00000100749; HGNC ID: 12718
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
355Phosphothreonine; by autocatalysis.
Location(AA) Modifications Resource
305PhosphothreoninePhospho.ELM 6.0
355Phosphothreonine (by autocatalysis).Swiss-Prot 53.0
355PhosphothreoninePhospho.ELM 6.0
390PhosphothreoninePhospho.ELM 6.0
Location(AA) Modification Resource
57N-linkedHMM predict
58Phosphoserine(CK1)HMM predict
194Phosphotyrosine(Syk)HMM predict
317Phosphotyrosine(INSR)HMM predict
386Phosphothreonine(PKC)HMM predict
390Phosphothreonine(PKC)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003384
  • Location:chr14 96333436-96417702
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 96333057 96333752 695 32
LIN9 G0GSE7516 96333009 96333662 653 101
Oct1 H2O2-HelaGSE14283 96318451 96318492 41 14965
Oct1 HelaGSE14283 96318451 96318492 41 14965
P300 T0-glioblastomaGSE21026 96333099 96333497 398 139
P300 T30-glioblastomaGSE21026 96332974 96333761 787 69
Rb SenescentGSE19898 96333232 96333597 365 22
p130 QuiescentGSE19898 96333119 96333617 498 69
p130 SenescentGSE19898 96333060 96333601 541 106
p130 shRbSenescentGSE19898 96333141 96333613 472 60
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Oct1 H2O2-HelaGSE14283 96428364 96428393 29 10676
Oct1 HelaGSE14283 96428360 96428399 39 10677
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 96389054 96389247 193 0
CTCF CD4SISSRdata 96389054 96389247 193 0
ER Fulvestrant-MCF7GSE14664 96394524 96394588 64 0
ER Fulvestrant-MCF7GSE14664 96394648 96394714 66 0
ETS1 JurkatGSE17954 96332972 96334480 1508 0
H3K4me3 colorectalcancer 96333951 96334560 609 0
H3ac HepG2E 96333983 96334910 927 0
Oct1 HelaGSE14283 96347195 96347224 29 0
PHF8 293TGSE20725 96333219 96334122 903 0
PHF8 HeLaGSE20725 96333128 96334258 1130 0
Rb shRbQuiescentGSE19898 96333349 96333576 227 0
Rb shRbSenescenceGSE19898 96333377 96333603 226 0
TAF k562GSE8489 96334197 96334801 604 0
USF1 HepG2E 96335195 96336247 1052 0
hScc1 BcellGSE12603 96388990 96389313 323 0
hScc1 CdLSGSE12603 96388920 96389418 498 0
p130 shRbQuiescentGSE19898 96333283 96333667 384 0
p130 shRbSenescentGSE19898 96333695 96334204 509 0
p63 keratinocytesGSE17611 96357337 96358084 747 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018