AutismKB 2.0

Annotation Detail for VRK2


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Basic Information Top
Gene Symbol:VRK2 ( - )
Gene Full Name: vaccinia related kinase 2
Band: 2p16.1
Quick LinksEntrez ID:7444; OMIM: 602169; Uniprot ID:VRK2_HUMAN; ENSEMBL ID: ENSG00000028116; HGNC ID: 12719
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
336Phosphothreonine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
135N-linkedHMM predict
183Phosphotyrosine(Syk)HMM predict
211N-linkedHMM predict
239S-palmitoylHMM predict
245S-palmitoylHMM predict
336Phosphothreonine(CDK)HMM predict
406Phosphoserine(ATM)HMM predict
430Phosphotyrosine(Syk)HMM predict
449Phosphoserine(PKC)HMM predict
456O-linkedHMM predict
458O-linkedHMM predict
459O-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_006296
  • Location:chr2 58127223-58240506
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 58125780 58126457 677 1105
H3ac HepG2E 58126788 58127244 456 208
Nanog hESGSE18292 58120094 58120524 430 6915
TAF k562GSE8489 58125053 58126457 1404 1469
TAF k562GSE8489 58126788 58127175 387 242
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER E2-MCF7GSE14664 58136208 58136243 35 0
ER Fulvestrant-MCF7GSE14664 58136209 58136246 37 0
Fos K562GSE19551 58227263 58227830 567 0
Jun K562GSE19551 58227364 58227795 431 0
Nanog hESGSE18292 58138463 58138968 505 0
Oct1 H2O2-HelaGSE14283 58193666 58193695 29 0
Oct1 HelaGSE14283 58136209 58136244 35 0
Oct1 HelaGSE14283 58148046 58148089 43 0
Oct1 HelaGSE14283 58165058 58165097 39 0
P300 T30-glioblastomaGSE21026 58188290 58189030 740 0
PHF8 HeLaGSE20725 58126627 58128442 1815 0
PHF8 Hs68minusFBSGSE20725 58126903 58128183 1280 0
PolII HeLaGSE12783 58187872 58189056 1184 0
RNAII Tamoxifen-MCF7GSE14664 58148046 58148085 39 0
Rb GrowingGSE19898 58211911 58212067 156 0
Sox2 hESGSE18292 58138293 58138960 667 0
TAF HelaGSE8489 58188384 58189277 893 0
TAF k562GSE8489 58128237 58129574 1337 0
hScc1 BcellGSE12603 58127138 58127508 370 0
p130 shRbSenescentGSE19898 58127654 58128167 513 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14311 mRNA VRK2 chr2 58185476 58298654 452 mRNA FANCL chr2 58298030 58380165Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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