AutismKB 2.0

Annotation Detail for VTN


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Basic Information Top
Gene Symbol:VTN ( V75,VN,VNT )
Gene Full Name: vitronectin
Band: 17q11.2
Quick LinksEntrez ID:7448; OMIM: 193190; Uniprot ID:VTNC_HUMAN; ENSEMBL ID: ENSG00000109072; HGNC ID: 12724
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
66Cell attachment site.
69Phosphothreonine; by CK2; in vitro.
75Sulfotyrosine.
76Phosphothreonine; by CK2; in vitro.
78Sulfotyrosine.
86N-linked (GlcNAc...).
169N-linked (GlcNAc...).
171Phosphoserine.
242N-linked (GlcNAc...).
282Sulfotyrosine (Potential).
312Phosphoserine.
397Phosphoserine; by PKA.
417Sulfotyrosine (Potential).
420Sulfotyrosine (Potential).
Location(AA) Modifications Resource
69Phosphothreonine; by CK2; in vitro.Swiss-Prot 53.0
69Phosphothreonine (CK2
75Sulfotyrosine (Probable).Swiss-Prot 53.0
76Phosphothreonine; by CK2; in vitro.Swiss-Prot 53.0
76Phosphothreonine (CK2
78Sulfotyrosine (Probable).Swiss-Prot 53.0
86N-linked (GlcNAc...).Swiss-Prot 53.0
169N-linked (GlcNAc...).Swiss-Prot 53.0
171PhosphoserinePhospho.ELM 6.0
171Phosphoserine.Swiss-Prot 53.0
242N-linked (GlcNAc...).Swiss-Prot 53.0
282Sulfotyrosine (Potential).Swiss-Prot 53.0
312Phosphoserine.Swiss-Prot 53.0
397Phosphoserine (by PKA).Swiss-Prot 53.0
397Phosphoserine (PKA
417Sulfotyrosine (Potential).Swiss-Prot 53.0
420Sulfotyrosine (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
75SulfotyrosineHMM predict
75Phosphotyrosine(Syk)HMM predict
75Phosphotyrosine(SRC)HMM predict
78SulfotyrosineHMM predict
86N-linkedHMM predict
169N-linkedHMM predict
355SulfotyrosineHMM predict
381Phosphoserine(ATM)HMM predict
383MethylarginineHMM predict
387MethylarginineHMM predict
397Phosphoserine(PKG)HMM predict
397Phosphoserine(PKA)HMM predict
406Phosphoserine(CK1)HMM predict
417Phosphotyrosine(Syk)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000638
  • Location:chr17 23718427-23721499
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
USF1 HepG2E 23721626 23722670 1044 649
USF2 HepG2E 23721466 23722670 1204 569
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 23720826 23721528 702 0
H3ac HepG2E 23720638 23721161 523 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018