AutismKB 2.0

Annotation Detail for WT1


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Basic Information Top
Gene Symbol:WT1 ( AWT1,GUD,NPHS4,WAGR,WIT-2,WT33 )
Gene Full Name: Wilms tumor 1
Band: 11p13
Quick LinksEntrez ID:7490; OMIM: 607102; Uniprot ID:WT1_HUMAN; ENSEMBL ID: ENSG00000184937; HGNC ID: 12796
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
410KTS motif.
Location(AA) Modifications Resource
365Phosphoserine (PKA
393Phosphoserine (PKA
Location(AA) Modification Resource
50O-linkedHMM predict
97Phosphoserine(CDK)HMM predict
103O-linkedHMM predict
118Phosphoserine(ATM)HMM predict
118O-linkedHMM predict
140Phosphoserine(ATM)HMM predict
153O-linkedHMM predict
163Phosphothreonine(MAPK)HMM predict
187Phosphoserine(IKK)HMM predict
193Phosphotyrosine(Abl)HMM predict
193Phosphotyrosine(Syk)HMM predict
193Phosphotyrosine(SRC)HMM predict
194Phosphoserine(IKK)HMM predict
194Phosphoserine(SRC)HMM predict
204O-linkedHMM predict
227Phosphotyrosine(Syk)HMM predict
257Phosphoserine(ATM)HMM predict
275N-linkedHMM predict
309Phosphothreonine(PKC)HMM predict
315Phosphoserine(CK2)HMM predict
315Phosphoserine(CAMK2)HMM predict
317Phosphothreonine(PKC)HMM predict
318Phosphoserine(CK1)HMM predict
348Phosphothreonine(PKC)HMM predict
365Phosphoserine(PKG)HMM predict
365Phosphoserine(CK1)HMM predict
378Phosphothreonine(PKA)HMM predict
378Phosphothreonine(PKC)HMM predict
388S-palmitoylHMM predict
395Phosphoserine(CK2)HMM predict
400Phosphothreonine(CDK)HMM predict
410Phosphoserine(PKG)HMM predict
421S-palmitoylHMM predict
441N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_000378
  • Location:chr11 32365900-32413662
  • strand:-
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 32352469 32352670 201 13331
CTCF CD4SISSRdata 32352469 32352670 201 13331
Fos K562GSE19551 32364711 32365357 646 867
Oct1 HelaGSE14283 32346045 32346082 37 19837
Oct1 HelaGSE14283 32354105 32354147 42 11775
Oct1 HelaGSE14283 32359661 32359712 51 6214
Oct1 HelaGSE14283 32365114 32365187 73 750
hScc1 BcellGSE12603 32352614 32352902 288 13143
hScc1 G2GSE9613 32352614 32353064 450 13062
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 32398712 32402359 3647 0
ER E2-MCF7GSE14664 32377210 32377246 36 0
FOXA1 DLD1GSE12801 32391505 32391670 165 0
FOXA1 MCF7GSE15244 32378306 32378707 401 0
GATA3 MCF7GSE15244 32398916 32400096 1180 0
H3K27me3 colorectalcancer 32406173 32408464 2291 0
H3K27me3 colorectalcancer 32410690 32412396 1706 0
NRSF pAbJurkat 32412642 32413175 533 0
Oct1 H2O2-HelaGSE14283 32398880 32398919 39 0
Oct1 HelaGSE14283 32375108 32375159 51 0
Oct1 HelaGSE14283 32398876 32398918 42 0
Oct1 HelaGSE14283 32403599 32403678 79 0
RARG MCF7GSE15244 32378306 32378743 437 0
TAF k562GSE8489 32410909 32412186 1277 0
hScc1 BcellGSE12603 32404858 32405488 630 0
hScc1 BcellGSE12603 32412605 32413299 694 0
hScc1 CdLSGSE12603 32404517 32405845 1328 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-1 hsa-mir-1-2 18 20368543
hsa-miR-1 hsa-mir-1-1 20 20368543
hsa-miR-126 hsa-mir-126 9 18776121
hsa-miR-126* hsa-mir-126 9 18776121
hsa-miR-133a hsa-mir-133a-1 18 20368543
hsa-miR-133a hsa-mir-133a-2 20 20368543
hsa-miR-133b hsa-mir-133b 6 20368543
hsa-miR-144 hsa-mir-144 17 20656931
hsa-miR-144* hsa-mir-144 17 20656931
hsa-miR-145 hsa-mir-145 5 18776121
hsa-miR-145* hsa-mir-145 5 18776121
hsa-miR-155 hsa-mir-155 21 20656931
hsa-miR-155* hsa-mir-155 21 20656931
hsa-miR-15a hsa-mir-15a 13 16204133
hsa-miR-15a* hsa-mir-15a 13 16204133
hsa-miR-16 hsa-mir-16-1 13 16204133
hsa-miR-16 hsa-mir-16-2 3 16204133
hsa-miR-181a hsa-mir-181a-2 9 18809607
hsa-miR-181a hsa-mir-181a-1 1 18809607
hsa-miR-181a* hsa-mir-181a-1 1 18809607
hsa-miR-181a-2* hsa-mir-181a-2 9 18809607
hsa-miR-181b hsa-mir-181b-1 1 18809607
hsa-miR-181b hsa-mir-181b-2 9 18809607
hsa-miR-181c hsa-mir-181c 19 18809607
hsa-miR-181c* hsa-mir-181c 19 18809607
hsa-miR-181d hsa-mir-181d 19 18809607
hsa-miR-221 hsa-mir-221 X 21076613
hsa-miR-221* hsa-mir-221 X 21076613
hsa-miR-23b hsa-mir-23b 9 18832437
hsa-miR-23b* hsa-mir-23b 9 18832437
hsa-miR-24 hsa-mir-24-1 9 18832437
hsa-miR-24 hsa-mir-24-2 19 18832437
hsa-miR-26a hsa-mir-26a-1 3 18832437
hsa-miR-26a hsa-mir-26a-2 12 18832437
hsa-miR-30a hsa-mir-30a 6 18776121
hsa-miR-30a* hsa-mir-30a 6 18776121
hsa-miR-451 hsa-mir-451 17 20656931
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018