AutismKB 2.0

Annotation Detail for XPO1


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Basic Information Top
Gene Symbol:XPO1 ( CRM1,DKFZp686B1823,emb )
Gene Full Name: exportin 1 (CRM1 homolog, yeast)
Band: 2p15
Quick LinksEntrez ID:7514; OMIM: 602559; Uniprot ID:XPO1_HUMAN; ENSEMBL ID: ENSG00000082898; HGNC ID: 12825
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
391Phosphoserine.
397Phosphoserine.
446N6-acetyllysine.
455N6-acetyllysine.
693N6-acetyllysine.
1031Phosphoserine.
Location(AA) Modifications Resource
1055PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
20Phosphoserine(ATM)HMM predict
159Phosphothreonine(PKC)HMM predict
162Phosphoserine(IKK)HMM predict
277Phosphoserine(ATM)HMM predict
279Phosphotyrosine(Syk)HMM predict
321N-linkedHMM predict
387O-linkedHMM predict
391Phosphoserine(CDC2)HMM predict
391Phosphoserine(IKK)HMM predict
391Phosphoserine(CDK)HMM predict
395Phosphoserine(CK1)HMM predict
485N-linkedHMM predict
634Phosphotyrosine(Syk)HMM predict
841Phosphotyrosine(EGFR)HMM predict
841SulfotyrosineHMM predict
915Phosphotyrosine(Syk)HMM predict
1055PhosphoserineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003400
  • Location:chr2 61558573-61618921
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Fos K562GSE19551 61618540 61619700 1160 199
LIN9 G0GSE7516 61618578 61619690 1112 213
LIN9 SGSE7516 61618709 61619690 981 278
Oct1 H2O2-HelaGSE14283 61627267 61627294 27 8359
Oct1 HelaGSE14283 61627263 61627295 32 8358
PHF8 HeLaGSE20725 61618271 61619904 1633 166
RNAII Tamoxifen-MCF7GSE14664 61634730 61634819 89 15853
Rb QuiescentGSE19898 61619052 61619427 375 318
Rb SenescentGSE19898 61618536 61619779 1243 236
p130 QuiescentGSE19898 61618736 61619205 469 49
p130 SenescentGSE19898 61618526 61620119 1593 401
p130 shRbQuiescentGSE19898 61618163 61620091 1928 206
p130 shRbSenescentGSE19898 61618656 61619760 1104 287
p130 G0GSE7516 61618608 61619450 842 108
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
Nanog hESGSE18292 61558262 61558480 218 203
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 61617177 61617460 283 0
FOXA1 MCF7GSE15244 61616929 61617781 852 0
H3K4me2 HCT116GSE10453 61616787 61617641 854 0
H3K4me3 colorectalcancer 61616517 61617841 1324 0
H3ac HepG2E 61616258 61618019 1761 0
Pol2 GM12878GSE19551 61616836 61618060 1224 0
RNAII Tamoxifen-MCF7GSE14664 61614249 61614347 98 0
RNAII Tamoxifen-MCF7GSE14664 61616359 61616397 38 0
TAF HelaGSE8489 61616443 61617745 1302 0
TAF k562GSE8489 61615352 61617817 2465 0
TFAP2C MCF7GSE21234 61618330 61619508 1178 0
USF1 HepG2E 61616481 61618019 1538 0
USF2 HepG2E 61616929 61618019 1090 0
hScc1 BcellGSE12603 61616929 61617460 531 0
hScc1 BcellGSE12603 61617781 61618217 436 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7a hsa-let-7a-1 9 20436454
hsa-let-7a hsa-let-7a-2 11 20436454
hsa-let-7a hsa-let-7a-3 22 20436454
hsa-let-7a* hsa-let-7a-1 9 20436454
hsa-let-7a* hsa-let-7a-3 22 20436454
hsa-let-7b hsa-let-7b 22 20436454
hsa-let-7b* hsa-let-7b 22 20436454
hsa-let-7c hsa-let-7c 21 20436454
hsa-let-7c* hsa-let-7c 21 20436454
hsa-let-7d hsa-let-7d 9 20436454
hsa-let-7d* hsa-let-7d 9 20436454
hsa-let-7e hsa-let-7e 19 20436454
hsa-let-7e* hsa-let-7e 19 20436454
hsa-let-7f hsa-let-7f-1 9 20436454
hsa-let-7f hsa-let-7f-2 X 20436454
hsa-let-7f-1* hsa-let-7f-1 9 20436454
hsa-let-7f-2* hsa-let-7f-2 X 20436454
hsa-let-7g hsa-let-7g 3 20436454
hsa-let-7g* hsa-let-7g 3 20436454
hsa-let-7i hsa-let-7i 12 20436454
hsa-let-7i* hsa-let-7i 12 20436454
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
14338 EST chr2 61621452 61622916 169 mRNA XPO1 chr2 61616719 61677069Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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