AutismKB 2.0

Annotation Detail for XRCC2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:XRCC2 ( DKFZp781P0919 )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 2
Band: 7q36.1
Quick LinksEntrez ID:7516; OMIM: 600375; Uniprot ID:XRCC2_HUMAN; ENSEMBL ID: ENSG00000196584; HGNC ID: 12829
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
247Phosphoserine.
249Phosphoserine.
Location(AA) Modifications Resource
Location(AA) Modification Resource
10Phosphoserine(CK1)HMM predict
10Phosphoserine(PKG)HMM predict
101Phosphoserine(CK2)HMM predict
101Phosphoserine(ATM)HMM predict
101Phosphoserine(CK1)HMM predict
101Phosphoserine(PKG)HMM predict
101Phosphoserine(PKA)HMM predict
103Phosphoserine(CK2)HMM predict
204Phosphoserine(CK1)HMM predict
204Phosphoserine(CK2)HMM predict
204Phosphoserine(CK2)HMM predict
205Phosphoserine(CK1)HMM predict
206O-linkedHMM predict
247Phosphoserine(ATM)HMM predict
247Phosphoserine(IKK)HMM predict
272IsoleucineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005431
  • Location:chr7 151974521-152004182
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TAFII hESGSE17917 152003991 152004423 432 25
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 151989596 151989844 248 0
CTCF G2GSE9613 152003873 152004144 271 0
E2F4 G0GSE7516 152003398 152004573 1175 0
ETS1 JurkatGSE17954 152003564 152004592 1028 0
H3K4me2 HCT116GSE10453 152003069 152003629 560 0
H3ac HepG2E 152003069 152003796 727 0
LIN9 G0GSE7516 152003069 152004595 1526 0
LIN9 SGSE7516 152003286 152004595 1309 0
Rb QuiescentGSE19898 152003850 152004438 588 0
Rb SenescentGSE19898 152003776 152004459 683 0
Rb shRbSenescenceGSE19898 152003815 152004288 473 0
hScc1 BcellGSE12603 152003796 152004304 508 0
hScc1 CdLSGSE12603 152003873 152004390 517 0
p130 QuiescentGSE19898 152003798 152004387 589 0
p130 SenescentGSE19898 152003327 152004594 1267 0
p130 shRbQuiescentGSE19898 152003724 152004326 602 0
p130 shRbSenescentGSE19898 152003728 152004557 829 0
p130 G0GSE7516 152003142 152004595 1453 0
p130 SGSE7516 152003509 152004390 881 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018