AutismKB 2.0

Annotation Detail for XRCC5


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Basic Information Top
Gene Symbol:XRCC5 ( FLJ39089,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV )
Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Band: 2q35
Quick LinksEntrez ID:7520; OMIM: 194364; Uniprot ID:XRCC5_HUMAN; ENSEMBL ID: ENSG00000079246; HGNC ID: 12833
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
144N6-acetyllysine.
195N6-acetyllysine.
258Phosphoserine.
265N6-acetyllysine.
332N6-acetyllysine.
577Phosphoserine; by PRKDC.
579Phosphoserine; by PRKDC (Probable).
580Phosphoserine; by PRKDC.
660N6-acetyllysine.
665N6-acetyllysine.
715Phosphothreonine; by PRKDC (Probable).
728EEXXXDL motif.
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_021141
  • Location:chr2 216682376-216779247
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 216681956 216682340 384 229
ETS1 JurkatGSE17954 216681635 216682874 1239 122
H3ac HepG2E 216680607 216683792 3185 177
HIF1 HypoHepG2 216681956 216682534 578 132
HIF1 NormHepG2 216681956 216682609 653 94
P300 T30-glioblastomaGSE21026 216681726 216682960 1234 34
PHF8 293TGSE20725 216681772 216682952 1180 15
Rb GrowingGSE19898 216681955 216682601 646 99
Rb QuiescentGSE19898 216682135 216682589 454 15
Rb shRbSenescenceGSE19898 216682050 216682433 383 135
TAF HelaGSE8489 216681956 216682240 284 279
TFAP2C MCF7GSE21234 216680770 216681105 335 1439
TFAP2C MCF7GSE21234 216681999 216682721 722 17
p130 QuiescentGSE19898 216682029 216682714 685 5
p130 SenescentGSE19898 216682013 216682731 718 5
p130 shRbSenescentGSE19898 216681943 216682753 810 29
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 216795729 216795971 242 16603
Fos K562GSE19551 216790399 216790909 510 11407
NFkBII GM12878GSE19485 216795225 216796909 1684 16820
NFkBII GM12892GSE19485 216795396 216796875 1479 16888
NFkBII GM15510GSE19485 216795366 216796882 1516 16877
NFkBII GM18526GSE19485 216795143 216796889 1746 16769
hScc1 CdLSGSE12603 216795729 216796040 311 16637
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 216687602 216687926 324 0
CTCF CD4GSE12889 216712970 216713222 252 0
CTCF CD4SISSRdata 216687602 216687926 324 0
CTCF CD4SISSRdata 216712970 216713222 252 0
CTCF G2GSE9613 216729825 216730151 326 0
H3K4me3 colorectalcancer 216682240 216683647 1407 0
H3ac HepG2E 216684917 216686286 1369 0
Myc hESGSE17917 216682316 216682565 249 0
PHF8 HeLaGSE20725 216681819 216682941 1122 0
PolII HeLaGSE12783 216681052 216683846 2794 0
Rb QuiescentGSE19898 216750114 216750224 110 0
Rb SenescentGSE19898 216682061 216682691 630 0
p130 SenescentGSE19898 216715572 216715829 257 0
p130 shRbQuiescentGSE19898 216681989 216682902 913 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018