AutismKB 2.0

Annotation Detail for YWHAB


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:YWHAB ( GW128,HS1,KCIP-1,YWHAA )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Band: 20q13.12
Quick LinksEntrez ID:7529; OMIM: 601289; Uniprot ID:1433B_HUMAN; ENSEMBL ID: ENSG00000166913; HGNC ID: 12849
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine; in 14-3-3 protein
2N-acetylthreonine; in 14-3-3 protein
6Phosphoserine.
70N6-acetyllysine.
117N6-acetyllysine.
186Phosphoserine (By similarity).
Location(AA) Modifications Resource
2N-acetylthreonine (By similarity).Swiss-Prot 53.0
59Phosphoserine (PKC delta;SD)Phospho.ELM 6.0
131Phosphoserine (PKC zeta)Phospho.ELM 6.0
142Phosphothreonine (PKC zeta)Phospho.ELM 6.0
185Phosphoserine (MAPK8)Phospho.ELM 6.0
186Phosphoserine (By similarity).Swiss-Prot 53.0
Location(AA) Modification Resource
21SulfotyrosineHMM predict
21Phosphotyrosine(Syk)HMM predict
60Phosphoserine(PKB)HMM predict
110N-linkedHMM predict
151Phosphotyrosine(EGFR)HMM predict
151Phosphotyrosine(Syk)HMM predict
175N-linkedHMM predict
186Phosphoserine(CDK)HMM predict
186Phosphoserine(CDC2)HMM predict
186PhosphoserineHMM predict
213Phosphotyrosine(EGFR)HMM predict
226N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003404
  • Location:chr20 42947757-42970573
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42929734 42929933 199 17924
CTCF CD4SISSRdata 42929734 42929933 199 17924
CTCF HelaGSE12889 42929745 42929968 223 17901
CTCF G2GSE9613 42929769 42929964 195 17891
H3ac HepG2E 42946907 42947464 557 572
PHF8 293TGSE20725 42947084 42948424 1340 4
Rb GrowingGSE19898 42947282 42947458 176 388
Rb GrowingGSE19898 42947477 42947663 186 188
Rb QuiescentGSE19898 42947323 42947695 372 249
Rb SenescentGSE19898 42947256 42947654 398 303
USF1 HepG2E 42946907 42947464 557 572
USF2 HepG2E 42946907 42947464 557 572
hScc1 BcellGSE12603 42929769 42929964 195 17891
hScc1 BcellGSE12603 42947442 42947745 303 164
hScc1 CdLSGSE12603 42929769 42929964 195 17891
hScc1 G2GSE9613 42929769 42929964 195 17891
p130 QuiescentGSE19898 42947460 42947643 183 206
p130 SenescentGSE19898 42947315 42947712 397 244
p130 shRbQuiescentGSE19898 42947163 42947685 522 334
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42973532 42973720 188 3053
CTCF CD4SISSRdata 42973532 42973720 188 3053
CTCF G2GSE9613 42973556 42973865 309 3137
TFAP2C MCF7GSE21234 42986543 42986996 453 16196
hScc1 BcellGSE12603 42971982 42972456 474 1646
hScc1 BcellGSE12603 42973556 42974011 455 3210
hScc1 BcellGSE12603 42977235 42977535 300 6812
hScc1 G2GSE9613 42973556 42974011 455 3210
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 42947267 42948257 990 0
H3K4me3 colorectalcancer 42948492 42949743 1251 0
H3ac HepG2E 42948271 42949743 1472 0
H3ac HepG2E 42950583 42951397 814 0
PHF8 HeLaGSE20725 42947665 42948407 742 0
Rb shRbSenescenceGSE19898 42948918 42949107 189 0
Rb shRbSenescenceGSE19898 42949323 42949546 223 0
p130 SenescentGSE19898 42964111 42964404 293 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
16409 mRNA YWHAB chr20 42947757 42970574 320 EST chr20 42970054 42970574Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved