AutismKB 2.0

Annotation Detail for YWHAG


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Basic Information Top
Gene Symbol:YWHAG ( 14-3-3GAMMA )
Gene Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Band: 7q11.23
Quick LinksEntrez ID:7532; OMIM: 605356; Uniprot ID:1433G_HUMAN; ENSEMBL ID: ENSG00000170027; HGNC ID: 12852
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
1N-acetylmethionine; in 14-3-3 protein
2N-acetylvaline; partial.
2N-acetylvaline; in 14-3-3 protein gamma,
117Phosphotyrosine (By similarity).
145Phosphothreonine.
Location(AA) Modifications Resource
2N-acetylvaline.Swiss-Prot 53.0
Location(AA) Modification Resource
20SulfotyrosineHMM predict
20Phosphotyrosine(Syk)HMM predict
29N-linkedHMM predict
34N-linkedHMM predict
59Phosphoserine(PKB)HMM predict
102Phosphoserine(CK1)HMM predict
111N-linkedHMM predict
117Phosphotyrosine(SRC)HMM predict
145Phosphothreonine(PKC)HMM predict
154Phosphotyrosine(SRC)HMM predict
178N-linkedHMM predict
183Phosphotyrosine(Syk)HMM predict
216Phosphotyrosine(EGFR)HMM predict
229N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012479
  • Location:chr7 75794052-75826251
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 75840703 75841045 342 14623
Fos K562GSE19551 75831618 75832520 902 5818
PHF8 293TGSE20725 75825498 75827091 1593 43
PHF8 HeLaGSE20725 75825471 75827044 1573 6
Rb shRbQuiescentGSE19898 75836010 75836165 155 9836
hScc1 CdLSGSE12603 75826128 75826926 798 276
p130 QuiescentGSE19898 75831950 75832221 271 5834
p130 SenescentGSE19898 75826371 75827228 857 548
p130 SenescentGSE19898 75831675 75832295 620 5734
p130 shRbQuiescentGSE19898 75826624 75827198 574 660
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 75784718 75785962 1244 8713
ER Fulvestrant-MCF7GSE14664 75788767 75788815 48 5262
Fos K562GSE19551 75784911 75785797 886 8699
Oct1 H2O2-HelaGSE14283 75787169 75787201 32 6868
Oct1 HelaGSE14283 75787169 75787205 36 6866
Oct1 HelaGSE14283 75788765 75788811 46 5265
PHF8 HeLaGSE20725 75784653 75786155 1502 8649
RNAII Tamoxifen-MCF7GSE14664 75788781 75788817 36 5254
TFAP2C MCF7GSE21234 75784992 75785641 649 8736
p130 QuiescentGSE19898 75785099 75785370 271 8818
p130 SenescentGSE19898 75785042 75785533 491 8765
p130 SenescentGSE19898 75785608 75785971 363 8263
p130 shRbQuiescentGSE19898 75785915 75786421 506 7885
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 75825316 75827100 1784 0
ETS1 JurkatGSE17954 75825165 75827142 1977 0
FoxA1 MCF7MACSdata 75799465 75799601 136 0
H3K4me2 HCT116GSE10453 75824862 75825397 535 0
H3K4me3 colorectalcancer 75824618 75825464 846 0
H3ac HepG2E 75824546 75825593 1047 0
Oct1 HelaGSE14283 75816484 75816527 43 0
PHF8 Hs68minusFBSGSE20725 75825687 75826656 969 0
TAF HelaGSE8489 75824795 75825542 747 0
TAF k562GSE8489 75824648 75825505 857 0
TFAP2C MCF7GSE21234 75805546 75805906 360 0
hScc1 BcellGSE12603 75825593 75826450 857 0
hScc1 G2GSE9613 75825361 75826525 1164 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
24197 EST chr7 75600762 75601203 436 mRNA YWHAG chr7 75600767 75632967Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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