Annotation Detail for YWHAZ
Basic Information Top
| Gene Symbol: | YWHAZ ( 14-3-3-zeta,KCIP-1,MGC111427,MGC126532,MGC138156,YWHAD ) |
|---|---|
| Gene Full Name: | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide |
| Band: | 8q22.3 |
| Quick Links | Entrez ID:7534; OMIM: 601288; Uniprot ID:1433Z_HUMAN; ENSEMBL ID: ENSG00000164924; HGNC ID: 12855 |
| Relate to Another Database: | SFARIGene; denovo-db |
| Location(AA) | Modification | |
|---|---|---|
| 1 | N-acetylmethionine. | |
| 3 | N6-acetyllysine. | |
| 49 | N6-acetyllysine. | |
| 58 | Phosphoserine; by PKA and PKB/AKT1. | |
| 68 | N6-acetyllysine. | |
| 115 | N6-acetyllysine. | |
| 120 | N6-acetyllysine. | |
| 184 | Phosphoserine; by MAPK8. | |
| 207 | Phosphoserine. | |
| 210 | Phosphoserine. | |
| 232 | Phosphothreonine; by CK1. | |
| Location(AA) | Modifications | Resource |
|---|---|---|
| 1 | N-acetylmethionine. | Swiss-Prot 53.0 |
| 58 | Phosphoserine (PKA | |
| 184 | Phosphoserine (By similarity). | Swiss-Prot 53.0 |
| 184 | Phosphoserine (MAPK8) | Phospho.ELM 6.0 |
| 232 | Phosphothreonine. | Swiss-Prot 53.0 |
| 232 | Phosphothreonine (CK1 alpha) | Phospho.ELM 6.0 |
| Location(AA) | Modification | Resource |
|---|---|---|
| 19 | Sulfotyrosine | HMM predict |
| 19 | Phosphotyrosine(Syk) | HMM predict |
| 58 | Phosphoserine(PKB) | HMM predict |
| 108 | N-linked | HMM predict |
| 110 | Phosphoserine(ATM) | HMM predict |
| 149 | Phosphotyrosine(Syk) | HMM predict |
| 149 | Phosphotyrosine(EGFR) | HMM predict |
| 173 | N-linked | HMM predict |
| 184 | Phosphoserine | HMM predict |
| 184 | Phosphoserine(CDC2) | HMM predict |
| 184 | Phosphoserine(CDK) | HMM predict |
| 207 | Phosphoserine(CK1) | HMM predict |
| 211 | Phosphotyrosine(Syk) | HMM predict |
| 224 | N-linked | HMM predict |
| 232 | Phosphothreonine | HMM predict |
- RefSeq ID: NM_003406
- Location:chr8 102000089-102034744
- strand:-
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| FOXA1 | MCF7 | GSE15244 | 102034620 | 102035367 | 747 | 249 |
| GATA3 | MCF7 | GSE15244 | 102034907 | 102035299 | 392 | 359 |
| H3ac | HepG2 | E | 102034654 | 102035329 | 675 | 247 |
| Nanog | hES | GSE18292 | 102041981 | 102042525 | 544 | 7509 |
| RARA | MCF7 | GSE15244 | 102034585 | 102035438 | 853 | 267 |
| RARG | MCF7 | GSE15244 | 102034714 | 102035329 | 615 | 277 |
| Rb | Growing | GSE19898 | 102054578 | 102054766 | 188 | 19928 |
| Sox2 | hES | GSE18292 | 102042140 | 102042395 | 255 | 7523 |
| No data |
| Transcrip Factors | Experimental Cell | Database | TF Binding Start | TF Binding End | TF Binding Length | The Distance to Gene |
|---|---|---|---|---|---|---|
| PHF8 | 293T | GSE20725 | 102032859 | 102035133 | 2274 | 0 |
| Rb | Quiescent | GSE19898 | 102033636 | 102033915 | 279 | 0 |
| Rb | Senescent | GSE19898 | 102033339 | 102034056 | 717 | 0 |
| hScc1 | Bcell | GSE12603 | 102033289 | 102033830 | 541 | 0 |
| hScc1 | CdLS | GSE12603 | 102033223 | 102033988 | 765 | 0 |
| p130 | Quiescent | GSE19898 | 102033533 | 102034078 | 545 | 0 |
| p130 | Senescent | GSE19898 | 102033397 | 102034075 | 678 | 0 |
| p130 | shRbSenescent | GSE19898 | 102033286 | 102034015 | 729 | 0 |
Validated miRNA targets