AutismKB 2.0

Annotation Detail for ZFP36


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Basic Information Top
Gene Symbol:ZFP36 ( G0S24,GOS24,NUP475,RNF162A,TIS11,TTP )
Gene Full Name: zinc finger protein 36, C3H type, homolog (mouse)
Band: 19q13.1
Quick LinksEntrez ID:7538; OMIM: 190700; Uniprot ID:TTP_HUMAN; ENSEMBL ID: ENSG00000128016; HGNC ID: 12862
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
60Phosphoserine (By similarity).
88Phosphoserine (By similarity).
90Phosphoserine (By similarity).
92Phosphothreonine.
93Phosphoserine (By similarity).
186Phosphoserine.
257Phosphothreonine (By similarity).
323Phosphoserine (By similarity).
Location(AA) Modifications Resource
66PhosphoserinePhospho.ELM 6.0
88PhosphoserinePhospho.ELM 6.0
92PhosphothreoninePhospho.ELM 6.0
169PhosphoserinePhospho.ELM 6.0
197PhosphoserinePhospho.ELM 6.0
218PhosphoserinePhospho.ELM 6.0
228PhosphoserinePhospho.ELM 6.0
276PhosphoserinePhospho.ELM 6.0
296PhosphoserinePhospho.ELM 6.0
Location(AA) Modification Resource
12Phosphoserine(MAPK)HMM predict
14Phosphoserine(CDC2)HMM predict
14Phosphoserine(ATM)HMM predict
14Phosphoserine(MAPK)HMM predict
29O-linkedHMM predict
35O-linkedHMM predict
39Phosphoserine(IKK)HMM predict
41Phosphoserine(CDC2)HMM predict
41O-linkedHMM predict
43Phosphoserine(ATM)HMM predict
45Phosphoserine(CK1)HMM predict
46Phosphoserine(IKK)HMM predict
46Phosphoserine(CDC2)HMM predict
48Phosphoserine(CK1)HMM predict
48O-linkedHMM predict
60Phosphoserine(PKB)HMM predict
60Phosphoserine(IKK)HMM predict
88Phosphoserine(ATM)HMM predict
88O-linkedHMM predict
90Phosphoserine(CDC2)HMM predict
90Phosphoserine(IKK)HMM predict
90Phosphoserine(ATM)HMM predict
90Phosphoserine(CDK)HMM predict
90O-linkedHMM predict
90PhosphoserineHMM predict
90O-linkedHMM predict
92O-linkedHMM predict
93Phosphoserine(CDC2)HMM predict
93O-linkedHMM predict
93Phosphoserine(IKK)HMM predict
93Phosphoserine(MAPK)HMM predict
95O-linkedHMM predict
97O-linkedHMM predict
98O-linkedHMM predict
98O-linkedHMM predict
100Phosphothreonine(CDK)HMM predict
100Phosphothreonine(MAPK)HMM predict
197O-linkedHMM predict
197Phosphoserine(PKB)HMM predict
197Phosphoserine(IKK)HMM predict
197Phosphoserine(CDC2)HMM predict
197Phosphoserine(PKA)HMM predict
197Phosphoserine(PKG)HMM predict
197Phosphoserine(CDK)HMM predict
207O-linkedHMM predict
214Phosphoserine(ATM)HMM predict
214O-linkedHMM predict
214Phosphoserine(CDC2)HMM predict
217O-linkedHMM predict
218Phosphoserine(ATM)HMM predict
228Phosphoserine(ATM)HMM predict
228Phosphoserine(MAPK)HMM predict
233O-linkedHMM predict
238Phosphothreonine(CDK)HMM predict
238Phosphothreonine(MAPK)HMM predict
246Phosphothreonine(PKA)HMM predict
249S-palmitoylHMM predict
250S-palmitoylHMM predict
257Phosphothreonine(PKA)HMM predict
284Phosphotyrosine(INSR)HMM predict
284Phosphotyrosine(Syk)HMM predict
289Phosphoserine(CK1)HMM predict
296Phosphoserine(CDC2)HMM predict
317ProlineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003407
  • Location:chr19 44589326-44591884
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 HeLaGSE20725 44588630 44589994 1364 15
Rb SenescentGSE19898 44586069 44586543 474 3021
TFAP2C MCF7GSE21234 44585915 44586694 779 3022
hScc1 BcellGSE12603 44586381 44586718 337 2777
hScc1 BcellGSE12603 44588942 44589709 767 1
p130 QuiescentGSE19898 44586119 44586293 174 3121
p130 QuiescentGSE19898 44586319 44586698 379 2818
p130 SenescentGSE19898 44585925 44586662 737 3033
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ER MCF7GSE19013 44591818 44592745 927 397
H3K4me2 HCT116GSE10453 44593318 44594077 759 1813
H3ac HepG2E 44593133 44594304 1171 1834
Pol2 GM12878GSE19551 44588685 44595541 6856 229
TFAP2C MCF7GSE21234 44591826 44592257 431 157
VDR GM10855-UnstimGSE22484 44588255 44595716 7461 101
VDR GM10855-stimGSE22484 44588351 44596112 7761 347
VDR GM10861-stimGSE22484 44588288 44596306 8018 413
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
PHF8 293TGSE20725 44588901 44589837 936 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-29a hsa-mir-29a 7 19247375
hsa-miR-29a* hsa-mir-29a 7 19247375
hsa-miR-29b hsa-mir-29b-1 7 19801654
hsa-miR-29b hsa-mir-29b-2 1 19801654
No data
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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