Annotation Detail for PTTG1IP

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Basic Information Top

Gene Symbol:	PTTG1IP ( C21orf1,C21orf3,PBF )
Gene Full Name:	pituitary tumor-transforming 1 interacting protein
Band:	21q22.3
Quick Links	Entrez ID:754; OMIM: 603784; Uniprot ID:PTTG_HUMAN; ENSEMBL ID: ENSG00000183255; HGNC ID: 13524
Relate to Another Database:	SFARIGene; denovo-db

Post Translation Modification

Location(AA)	Modifications	Resource
45	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0
54	N-linked (GlcNAc...) (Potential).	Swiss-Prot 53.0

Validated transcription factor binding site by ChIP-Chip and ChIP-Seq

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
H3ac	HepG2	E	45119834	45120013	179	1755
Rb	shRbQuiescent	GSE19898	45121059	45121311	252	3017
TFAP2C	MCF7	GSE21234	45118836	45119334	498	917
hScc1	Bcell	GSE12603	45117345	45119071	1726	40
hScc1	CdLS	GSE12603	45117674	45119327	1653	332
hScc1	CdLS	GSE12603	45119834	45120083	249	1790

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length	The Distance to Gene
USF1	HepG2	E	45078569	45079039	470	15137
hScc1	Bcell	GSE12603	45081262	45081691	429	12464
hScc1	Bcell	GSE12603	45091510	45092364	854	2004
hScc1	Bcell	GSE12603	45093469	45093811	342	301

Transcrip Factors	Experimental Cell	Database	TF Binding Start	TF Binding End	TF Binding Length
CTCF	G2	GSE9613	45107371	45107746	375
ER	MCF7	GSE19013	45114282	45115034	752
FOXA1	MCF7	GSE15244	45102330	45102585	255
FOXA1	MCF7	GSE15244	45109409	45110514	1105
FOXA1	MCF7	GSE15244	45116114	45117345	1231
Gata2	K562	GSE18868	45097861	45099893	2032
H3K4me2	HCT116	GSE10453	45115572	45117066	1494
H3K4me3	colorectal	cancer	45116441	45117066	625
H3ac	HepG2	E	45114895	45117205	2310
PHF8	HeLa	GSE20725	45117389	45118935	1546
RARA	MCF7	GSE15244	45102374	45102585	211
RARA	MCF7	GSE15244	45114895	45115572	677
RARA	MCF7	GSE15244	45116513	45117101	588
RARG	MCF7	GSE15244	45102374	45102585	211
RARG	MCF7	GSE15244	45114895	45115572	677
RARG	MCF7	GSE15244	45115970	45117101	1131
TFAP2C	MCF7	GSE21234	45102453	45103481	1028
TFAP2C	MCF7	GSE21234	45116169	45116726	557
hScc1	Bcell	GSE12603	45098125	45098681	556
hScc1	Bcell	GSE12603	45106927	45107746	819
hScc1	Bcell	GSE12603	45109952	45110487	535
p130	shRbSenescent	GSE19898	45116233	45116494	261

Validated miRNA targets

Micro RNA Name	Stem Loop Name	The chromosome that miRNA located	Publication
hsa-miR-1	hsa-mir-1-2	18	15685193
hsa-miR-1	hsa-mir-1-1	20	15685193
hsa-miR-124	hsa-mir-124-1	8	15685193
hsa-miR-124	hsa-mir-124-2	8	15685193
hsa-miR-124	hsa-mir-124-3	20	15685193
hsa-miR-373	hsa-mir-373	19	15685193
hsa-miR-373*	hsa-mir-373	19	15685193

ID in Tarbase	Data Type	Support Type	miRNA	Gene	Direct Support	Publication
376	Unknown	MicroArray	miR-124	PTTG1IP	n_a	15685193
Ensembl	Protein Type	Differentially expressed in	Pathology or Event	Mis Regulation	Gene Expression	Tumour Involvement
ENSG00000183255		G1-to-S transition	n_a	n_a	"epithelium, squamous cell, lymphoblast, lymphocyte, leukocyte, muscle cell"	"benign tumour, malignant tumour, carcinoma, leukaemia, non-Hodgkin's, sarcoma"

Cis-Nats regulation

Cluster ID	Plue Type	Plus Gene Name	Plus Chromosome	Plus Start	Plus End	Overlap Length	Minus Type	Minus Gene Name	Minus Chromosome	Minus Star	Minus End	Type
17042	EST		chr21	45093907	45094277	245	mRNA	PTTG1IP	chr21	45093940	45118169	Sense/Antisense (SA) pairs

Simple Query:

Paper Collected: 6/30/2018

Last Update: 8/26/2018