AutismKB 2.0

Annotation Detail for MPPED1


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Basic Information Top
Gene Symbol:MPPED1 ( 239AB,C22orf1,FAM1A,FLJ50009,FLJ54633,FLJ59965,FLJ78907,MGC88045 )
Gene Full Name: metallophosphoesterase domain containing 1
Band: 22q13.2
Quick LinksEntrez ID:758; OMIM: 602112; Uniprot ID:MPPD1_HUMAN; ENSEMBL ID: ENSG00000186732; HGNC ID: 1306
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
28Phosphoserine(ATM)HMM predict
53N-linkedHMM predict
55O-linkedHMM predict
98Phosphothreonine(CDK)HMM predict
100Phosphoserine(IKK)HMM predict
168Phosphotyrosine(Syk)HMM predict
181Phosphotyrosine(INSR)HMM predict
181Phosphotyrosine(Syk)HMM predict
209Phosphoserine(CDC2)HMM predict
299Phosphotyrosine(INSR)HMM predict
301N-linkedHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001044370
  • Location:chr22 42137963-42234127
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 42123198 42123581 383 14574
CTCF G2GSE9613 42125180 42125611 431 12568
ER MCF7GSE19013 42125593 42126360 767 11987
Fos K562GSE19551 42125381 42125656 275 12445
FoxA1 MCF7MACSdata 42123034 42123175 141 14859
H3ac HepG2E 42124141 42125429 1288 13179
H3ac HepG2E 42126934 42128162 1228 10416
NRSF JurkatGSE13047 42133077 42133908 831 4471
NRSF JurkatSISSRdata 42133082 42133516 434 4665
NRSF mAbJurkat 42133159 42133791 632 4489
NRSF-mono JurkatQuESTdata 42133013 42133901 888 4507
NRSF-poly JurkatQuESTdata 42133077 42133799 722 4526
USF1 HepG2E 42124104 42126536 2432 12644
USF1 HepG2E 42126934 42128162 1228 10416
USF2 HepG2E 42124141 42126162 2021 12812
hScc1 BcellGSE12603 42137490 42138319 829 59
p63 keratinocytesGSE17611 42130279 42131266 987 7191
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
hScc1 BcellGSE12603 42243307 42243721 414 9387
p63 keratinocytesGSE17611 42238465 42239455 990 4833
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 42207475 42207644 169 0
CTCF CD4SISSRdata 42207475 42207644 169 0
CTCF JurkatGSE12889 42207470 42207618 148 0
CTCF G2GSE9613 42175347 42175955 608 0
CTCF G2GSE9613 42202372 42202821 449 0
NRSF JurkatGSE13047 42174839 42176317 1478 0
NRSF mAbJurkat 42172038 42173525 1487 0
NRSF mAbJurkat 42174744 42176076 1332 0
NRSF-mono JurkatQuESTdata 42174858 42175640 782 0
NRSF-poly JurkatQuESTdata 42174839 42175714 875 0
RARA MCF7GSE15244 42200425 42200802 377 0
RARG MCF7GSE15244 42148304 42148690 386 0
hScc1 BcellGSE12603 42152613 42152903 290 0
hScc1 BcellGSE12603 42166277 42166760 483 0
hScc1 BcellGSE12603 42207310 42207723 413 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018