AutismKB 2.0

Annotation Detail for ZNF74


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Basic Information Top
Gene Symbol:ZNF74 ( Cos52,ZNF520,Zfp520 )
Gene Full Name: zinc finger protein 74
Band: 22q11.21
Quick LinksEntrez ID:7625; OMIM: 194548; Uniprot ID:ZNF74_HUMAN; ENSEMBL ID: ENSG00000185252; HGNC ID: 13144
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
15Phosphoserine(ATM)HMM predict
21Phosphoserine(CK1)HMM predict
39Phosphoserine(CK1)HMM predict
62Phosphoserine(CDC2)HMM predict
159Phosphoserine(IKK)HMM predict
159Phosphoserine(ATM)HMM predict
221N-linkedHMM predict
238MethylarginineHMM predict
252S-palmitoylHMM predict
275Phosphotyrosine(Jak)HMM predict
308S-palmitoylHMM predict
344Phosphoserine(IKK)HMM predict
382Phosphothreonine(PKC)HMM predict
403Phosphothreonine(PKC)HMM predict
512Phosphoserine(IKK)HMM predict
565N-linkedHMM predict
636Phosphoserine(CAMK2)HMM predict
643AsparagineHMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003426
  • Location:chr22 19078479-19092750
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 19077890 19079036 1146 17
P300 T0-glioblastomaGSE21026 19077887 19078927 1040 73
P300 T30-glioblastomaGSE21026 19077897 19078835 938 114
PHF8 Hs68minusFBSGSE20725 19077615 19079226 1611 59
TAF k562GSE8489 19075515 19075873 358 2786
TAFII hESGSE17917 19078171 19078627 456 81
p130 QuiescentGSE19898 19077981 19078409 428 285
p130 SenescentGSE19898 19077854 19078526 672 290
p130 shRbQuiescentGSE19898 19077804 19078611 807 272
p130 shRbSenescentGSE19898 19078006 19078652 646 151
p63 keratinocytesGSE17611 19064759 19065328 569 13436
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 19079359 19079726 367 0
Myc hESGSE17917 19078313 19078679 366 0
PHF8 293TGSE20725 19077682 19079450 1768 0
hScc1 BcellGSE12603 19089911 19090958 1047 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018