AutismKB 2.0

Annotation Detail for MKRN3


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Basic Information Top
Gene Symbol:MKRN3 ( D15S9,MGC88288,RNF63,ZFP127,ZNF127 )
Gene Full Name: makorin ring finger protein 3
Band: 15q11.2
Quick LinksEntrez ID:7681; OMIM: 603856; Uniprot ID:MKRN3_HUMAN; ENSEMBL ID: ENSG00000179455; HGNC ID: 7114
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
No data
No data
Location(AA) Modification Resource
133O-linkedHMM predict
133Phosphoserine(CDC2)HMM predict
165Phosphoserine(IKK)HMM predict
167Phosphoserine(CK1)HMM predict
336N-linkedHMM predict
343S-palmitoylHMM predict
418Phosphotyrosine(Syk)HMM predict
418SulfotyrosineHMM predict
502Phosphotyrosine(INSR)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005664
  • Location:chr15 21361546-21364652
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
AR prostate-cancerGSE14092 21342339 21342957 618 18899
ER E2-MCF7GSE14664 21347917 21347953 36 13612
ER E2-MCF7GSE14664 21350575 21350607 32 10956
ER E2-MCF7GSE14664 21359570 21359605 35 1959
Oct1 H2O2-HelaGSE14283 21359573 21359608 35 1956
Oct1 HelaGSE14283 21347914 21347950 36 13615
Oct1 HelaGSE14283 21359573 21359604 31 1958
TAF k562GSE8489 21361015 21361854 839 112
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
GABP k562GSE8489 21365083 21365938 855 858
Oct1 HelaGSE14283 21374452 21374479 27 9813
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
ETS1 JurkatGSE17954 21361275 21362871 1596 0
GABP k562GSE8489 21361015 21363852 2837 0
Myc K562GSE19551 21361511 21362715 1204 0
P300 T30-glioblastomaGSE21026 21361416 21362748 1332 0
PHF8 HeLaGSE20725 21361608 21362580 972 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
8515 mRNA MKRN3 chr15 21361956 21407800 2240 EST chr15 21380346 21382586 Non-exonic Bidirectional (NOB) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018