AutismKB 2.0

Annotation Detail for ZBTB16


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Basic Information Top
Gene Symbol:ZBTB16 ( PLZF,ZNF145 )
Gene Full Name: zinc finger and BTB domain containing 16
Band: 11q23.2
Quick LinksEntrez ID:7704; OMIM: 176797; Uniprot ID:ZBT16_HUMAN; ENSEMBL ID: ENSG00000109906; HGNC ID: 12930
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
76Phosphoserine; by PDPK (Potential).
184Phosphoserine; by PDPK (Potential).
197Phosphoserine; by PDPK (Potential).
256Phosphoserine; by PDPK (Potential).
282Phosphothreonine; by PDPK (Potential).
628Phosphoserine; by PDPK (Potential).
Location(AA) Modifications Resource
76Phosphoserine (by PDPK) (Potential).Swiss-Prot 53.0
184Phosphoserine (by PDPK) (Potential).Swiss-Prot 53.0
197Phosphoserine (by PDPK) (Potential).Swiss-Prot 53.0
256Phosphoserine (by PDPK) (Potential).Swiss-Prot 53.0
282Phosphothreonine (by PDPK) (Potential).Swiss-Prot 53.0
628Phosphoserine (by PDPK) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
13N-linkedHMM predict
131N-linkedHMM predict
162Phosphoserine(CK2)HMM predict
162PhosphoserineHMM predict
166Phosphoserine(CK1)HMM predict
166Phosphoserine(CK2)HMM predict
168Phosphotyrosine(INSR)HMM predict
168Phosphotyrosine(Syk)HMM predict
168Phosphotyrosine(EGFR)HMM predict
170Phosphoserine(CAMK2)HMM predict
184Phosphoserine(ATM)HMM predict
186Phosphoserine(CK2)HMM predict
190Phosphoserine(IKK)HMM predict
197Phosphoserine(CDC2)HMM predict
253Phosphoserine(ATM)HMM predict
263Phosphoserine(CK1)HMM predict
282Phosphothreonine(MAPK)HMM predict
282Phosphothreonine(CDK)HMM predict
286O-linkedHMM predict
317O-linkedHMM predict
351Phosphoserine(ATM)HMM predict
495S-palmitoylHMM predict
524N-linkedHMM predict
546Phosphotyrosine(Syk)HMM predict
641Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001018011
  • Location:chr11 113436497-113626603
  • strand:+
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 113637070 113637240 170 10552
CTCF CD4SISSRdata 113637070 113637240 170 10552
CTCF JurkatGSE12889 113628036 113628282 246 1556
Oct1 HelaGSE14283 113632638 113632737 99 6084
Oct1 HelaGSE14283 113635321 113635351 30 8733
hScc1 BcellGSE12603 113636485 113637205 720 10242
hScc1 BcellGSE12603 113638406 113639151 745 12175
hScc1 CdLSGSE12603 113636661 113637205 544 10330
hScc1 G2GSE9613 113636204 113637205 1001 10101
hScc1 G2GSE9613 113638406 113639151 745 12175
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP JurkatGSE17954 113452822 113454805 1983 0
CBP JurkatGSE17954 113457944 113459692 1748 0
CBP T30-glioblastomaGSE21026 113573761 113574443 682 0
CTCF CD4GSE12889 113572323 113572479 156 0
CTCF CD4SISSRdata 113572323 113572479 156 0
CTCF HelaGSE12889 113556472 113556708 236 0
ER E2-MCF7GSE14664 113465800 113465876 76 0
ER E2-MCF7GSE14664 113472144 113472264 120 0
ER E2-MCF7GSE14664 113537558 113537590 32 0
ER E2-MCF7GSE14664 113545394 113545426 32 0
ER E2-MCF7GSE14664 113581576 113581614 38 0
FOXA1 DLD1GSE12801 113453566 113454715 1149 0
FOXA1 DLD1GSE12801 113485314 113485705 391 0
FOXA1 DLD1GSE12801 113535838 113536417 579 0
FOXA1 MCF7GSE15244 113485096 113485740 644 0
FOXA1 MCF7GSE15244 113535456 113536306 850 0
Gata2 K562GSE18868 113523583 113524295 712 0
Gata2 K562GSE18868 113591532 113592721 1189 0
Myc K562GSE19551 113535842 113536400 558 0
NRSF pAbJurkat 113540767 113541229 462 0
Oct1 H2O2-HelaGSE14283 113444401 113444435 34 0
Oct1 H2O2-HelaGSE14283 113452896 113452936 40 0
Oct1 H2O2-HelaGSE14283 113453973 113454007 34 0
Oct1 H2O2-HelaGSE14283 113516260 113516291 31 0
Oct1 H2O2-HelaGSE14283 113520758 113520784 26 0
Oct1 H2O2-HelaGSE14283 113523495 113523524 29 0
Oct1 H2O2-HelaGSE14283 113568939 113568966 27 0
Oct1 H2O2-HelaGSE14283 113569799 113569828 29 0
Oct1 HelaGSE14283 113452889 113452938 49 0
Oct1 HelaGSE14283 113453967 113454011 44 0
Oct1 HelaGSE14283 113460540 113460569 29 0
Oct1 HelaGSE14283 113467742 113467769 27 0
Oct1 HelaGSE14283 113486615 113486656 41 0
Oct1 HelaGSE14283 113488129 113488173 44 0
Oct1 HelaGSE14283 113494453 113494482 29 0
Oct1 HelaGSE14283 113516262 113516292 30 0
Oct1 HelaGSE14283 113522300 113522326 26 0
Oct1 HelaGSE14283 113523496 113523525 29 0
Oct1 HelaGSE14283 113533147 113533173 26 0
Oct1 HelaGSE14283 113535528 113535573 45 0
Oct1 HelaGSE14283 113552258 113552295 37 0
Oct1 HelaGSE14283 113581582 113581614 32 0
Oct1 HelaGSE14283 113614812 113614842 30 0
P300 T30-glioblastomaGSE21026 113573542 113574416 874 0
RARA MCF7GSE15244 113578099 113578313 214 0
RNAII Tamoxifen-MCF7GSE14664 113461586 113461674 88 0
hScc1 BcellGSE12603 113436550 113437005 455 0
hScc1 CdLSGSE12603 113451932 113452301 369 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-miR-146a hsa-mir-146a 5 18568019
hsa-miR-146a* hsa-mir-146a 5 18568019
hsa-miR-221 hsa-mir-221 X 18417445
hsa-miR-221* hsa-mir-221 X 18417445
hsa-miR-222 hsa-mir-222 X 18417445
hsa-miR-222* hsa-mir-222 X 18417445
No data
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
5211 mRNA ZBTB16 chr11 113436438 113626568 78 mRNA chr11 113436236 113437471Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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