AutismKB 2.0

Annotation Detail for TRIM25


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Basic Information Top
Gene Symbol:TRIM25 ( EFP,RNF147,Z147,ZNF147 )
Gene Full Name: tripartite motif-containing 25
Band: 17q23.1
Quick LinksEntrez ID:7706; OMIM: 600453; Uniprot ID:TRI25_HUMAN; ENSEMBL ID: ENSG00000121060; HGNC ID: 12932
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
91Phosphothreonine.
100Phosphoserine.
273N6-acetyllysine.
278Phosphotyrosine.
320N6-acetyllysine.
567N6-acetyllysine.
Location(AA) Modifications Resource
278Phosphotyrosine.Swiss-Prot 53.0
278PhosphotyrosinePhospho.ELM 6.0
Location(AA) Modification Resource
16S-palmitoylHMM predict
38N-linkedHMM predict
48Phosphotyrosine(Jak)HMM predict
97O-linkedHMM predict
97Phosphoserine(IKK)HMM predict
97Phosphoserine(PKG)HMM predict
100Phosphoserine(MAPK)HMM predict
122S-palmitoylHMM predict
158Phosphoserine(PKG)HMM predict
187Phosphoserine(MAPK)HMM predict
190O-linkedHMM predict
195O-linkedHMM predict
245Phosphotyrosine(Syk)HMM predict
290Phosphothreonine(PKC)HMM predict
290Phosphothreonine(CK2)HMM predict
300Phosphothreonine(PKC)HMM predict
359Phosphothreonine(MAPK)HMM predict
362O-linkedHMM predict
373Phosphothreonine(CDK)HMM predict
427Phosphothreonine(PKC)HMM predict
429O-linkedHMM predict
432N-linkedHMM predict
575Phosphothreonine(PKA)HMM predict
625Phosphoserine(IKK)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_005082
  • Location:chr17 52320268-52346407
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3K4me3 colorectalcancer 52347288 52347646 358 1060
H3ac HepG2E 52346826 52347646 820 829
Pol2 GM12878GSE19551 52345974 52347057 1083 108
RARA MCF7GSE15244 52347978 52348533 555 1848
STAT1 HeLaGSE12782 52344250 52349807 5557 621
STAT1 HeLaGSE12783 52344146 52349807 5661 569
TAF HelaGSE8489 52346756 52347646 890 794
TAF k562GSE8489 52346722 52347646 924 777
USF1 HepG2E 52346625 52347646 1021 728
USF1 HepG2E 52347978 52348533 555 1848
p130 SenescentGSE19898 52346375 52346843 468 202
p130 shRbQuiescentGSE19898 52346549 52347013 464 374
p130 shRbSenescentGSE19898 52348408 52348681 273 2137
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
TFAP2C MCF7GSE21234 52318678 52319375 697 1242
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 52324215 52324382 167 0
CTCF CD4SISSRdata 52324215 52324382 167 0
CTCF G2GSE9613 52323629 52324462 833 0
CTCF G2GSE9613 52345533 52346397 864 0
ER MCF7GSE19013 52323105 52323842 737 0
H3K4me2 HCT116GSE10453 52344427 52344946 519 0
H3K4me3 colorectalcancer 52344427 52344946 519 0
H3ac HepG2E 52342078 52342951 873 0
H3ac HepG2E 52344427 52344946 519 0
H3ac HepG2E 52345533 52345726 193 0
NFkBII GM12892GSE19485 52344499 52347285 2786 0
PHF8 HeLaGSE20725 52345520 52347295 1775 0
RARA MCF7GSE15244 52344427 52344847 420 0
RARG MCF7GSE15244 52342480 52343303 823 0
RARG MCF7GSE15244 52344427 52344946 519 0
TFAP2C MCF7GSE21234 52342539 52343520 981 0
USF1 HepG2E 52342078 52343154 1076 0
USF1 HepG2E 52344427 52344946 519 0
USF1 HepG2E 52345533 52345726 193 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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