AutismKB 2.0

Annotation Detail for LUZP1


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Basic Information Top
Gene Symbol:LUZP1 ( FLJ35697,KIAA0601,LUZP )
Gene Full Name: leucine zipper protein 1
Band: 1p36.12
Quick LinksEntrez ID:7798; OMIM: 601422; Uniprot ID:LUZP1_HUMAN; ENSEMBL ID: ENSG00000169641; HGNC ID: 14985
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
2N-acetylalanine.
338Phosphoserine.
394Phosphoserine.
570Phosphoserine.
574Phosphoserine.
659Phosphoserine.
677Phosphothreonine.
679Phosphothreonine.
690Phosphoserine.
745Phosphoserine.
805Phosphoserine.
905Phosphoserine.
956Phosphoserine.
Location(AA) Modifications Resource
338Phosphoserine.Swiss-Prot 53.0
338PhosphoserinePhospho.ELM 6.0
394Phosphoserine.Swiss-Prot 53.0
394PhosphoserinePhospho.ELM 6.0
659Phosphoserine.Swiss-Prot 53.0
659PhosphoserinePhospho.ELM 6.0
690Phosphoserine.Swiss-Prot 53.0
690PhosphoserinePhospho.ELM 6.0
745Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
57Phosphoserine(IKK)HMM predict
101N-linkedHMM predict
140Phosphoserine(CK1)HMM predict
146N-linkedHMM predict
148Phosphothreonine(PKC)HMM predict
168Phosphoserine(CK1)HMM predict
263Phosphotyrosine(Jak)HMM predict
269N-linkedHMM predict
273N-linkedHMM predict
326Phosphotyrosine(Syk)HMM predict
326SulfotyrosineHMM predict
394Phosphoserine(ATM)HMM predict
413N-linkedHMM predict
418N-linkedHMM predict
423Phosphoserine(CDC2)HMM predict
427Phosphothreonine(PKC)HMM predict
443O-linkedHMM predict
459Phosphoserine(CK2)HMM predict
460Phosphoserine(ATM)HMM predict
467Phosphoserine(PKG)HMM predict
531O-linkedHMM predict
534Phosphoserine(CK1)HMM predict
548N-linkedHMM predict
573Phosphoserine(PKG)HMM predict
573Phosphoserine(CK1)HMM predict
574Phosphoserine(PKA)HMM predict
574Phosphoserine(PKA)HMM predict
574Phosphoserine(CK1)HMM predict
574Phosphoserine(PKG)HMM predict
575Phosphoserine(PKA)HMM predict
593Phosphoserine(IKK)HMM predict
639Phosphoserine(ATM)HMM predict
659Phosphoserine(CK2)HMM predict
659PhosphoserineHMM predict
675N-linkedHMM predict
679Phosphothreonine(MAPK)HMM predict
679Phosphothreonine(CDC2)HMM predict
696Phosphothreonine(PKC)HMM predict
724Phosphoserine(PKG)HMM predict
724Phosphoserine(IKK)HMM predict
745Phosphoserine(CDC2)HMM predict
747MethylarginineHMM predict
793O-linkedHMM predict
797O-linkedHMM predict
804Phosphoserine(CK1)HMM predict
805Phosphoserine(CDK)HMM predict
805Phosphoserine(CDC2)HMM predict
820Phosphoserine(PKB)HMM predict
833Phosphoserine(CK1)HMM predict
872Phosphothreonine(PKC)HMM predict
898Phosphothreonine(PKC)HMM predict
919Phosphothreonine(PKC)HMM predict
952Phosphotyrosine(Abl)HMM predict
961Phosphoserine(CK1)HMM predict
990O-linkedHMM predict
995Phosphoserine(IKK)HMM predict
1004Phosphothreonine(PKC)HMM predict
1069Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_033631
  • Location:chr1 23284037-23367924
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
H3ac HepG2E 23368755 23369352 597 1129
Oct1 HelaGSE14283 23377912 23377949 37 10006
PHF8 Hs68plusFBSGSE20725 23376448 23377585 1137 9092
USF1 HepG2E 23368755 23369352 597 1129
USF2 HepG2E 23368755 23369352 597 1129
hScc1 BcellGSE12603 23376285 23377184 899 8810
p130 SenescentGSE19898 23376482 23376764 282 8699
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 23297876 23298088 212 0
CTCF CD4SISSRdata 23297876 23298088 212 0
CTCF G2GSE9613 23297581 23298284 703 0
CTCF G2GSE9613 23366714 23367139 425 0
H3ac HepG2E 23365949 23366566 617 0
NFkBII GM12892GSE19485 23366729 23368503 1774 0
Oct1 H2O2-HelaGSE14283 23323976 23324018 42 0
Oct1 HelaGSE14283 23323967 23324018 51 0
PolII HeLaGSE12783 23366175 23368273 2098 0
hScc1 BcellGSE12603 23297653 23298384 731 0
hScc1 BcellGSE12603 23367485 23368076 591 0
hScc1 CdLSGSE12603 23297462 23298594 1132 0
hScc1 G2GSE9613 23297543 23298384 841 0
p130 SenescentGSE19898 23367480 23367672 192 0
p130 SenescentGSE19898 23367827 23368007 180 0
p63 keratinocytesGSE17611 23366171 23367094 923 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
1065 Unknown pSILAC miR-16 LUZP1 down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000169641 n_a n_a n_a "macrophage, muscle cell, lymphocyte" "benign tumour, malignant tumour, carcinoma, sarcoma, "
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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