AutismKB 2.0

Annotation Detail for LRP8


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Basic Information Top
Gene Symbol:LRP8 ( APOER2,HSZ75190,MCI1 )
Gene Full Name: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Band: 1p32.3
Quick LinksEntrez ID:7804; OMIM: 602600; Uniprot ID:LRP8_HUMAN; ENSEMBL ID: ENSG00000157193; HGNC ID: 6700
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
176N-linked (GlcNAc...) (Potential).
441N-linked (GlcNAc...) (Potential).
518N-linked (GlcNAc...) (Potential).
538N-linked (GlcNAc...) (Potential).
772N-linked (GlcNAc...) (Potential).
807N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
176N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
441N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
518N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
538N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
772N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
807N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
76Phosphoserine(CK2)HMM predict
253O-linkedHMM predict
254O-linkedHMM predict
289PhosphoserineHMM predict
498Phosphoserine(MAPK)HMM predict
518N-linkedHMM predict
533Phosphothreonine(PKC)HMM predict
533Phosphothreonine(PKA)HMM predict
540Phosphoserine(CK1)HMM predict
702Phosphotyrosine(Jak)HMM predict
711O-linkedHMM predict
718O-linkedHMM predict
740Phosphoserine(IKK)HMM predict
740O-linkedHMM predict
741O-linkedHMM predict
742Phosphoserine(IKK)HMM predict
743O-linkedHMM predict
744O-linkedHMM predict
745O-linkedHMM predict
757O-linkedHMM predict
769Phosphothreonine(PKA)HMM predict
772N-linkedHMM predict
777Phosphothreonine(CDK)HMM predict
781O-linkedHMM predict
786O-linkedHMM predict
795Phosphoserine(IKK)HMM predict
795O-linkedHMM predict
795Phosphoserine(PKB)HMM predict
795Phosphoserine(PKG)HMM predict
797O-linkedHMM predict
799O-linkedHMM predict
799O-linkedHMM predict
800O-linkedHMM predict
802Phosphoserine(IKK)HMM predict
802O-linkedHMM predict
802Phosphoserine(CDC2)HMM predict
807N-linkedHMM predict
809Phosphoserine(ATM)HMM predict
856Phosphothreonine(PKA)HMM predict
869Phosphothreonine(PKC)HMM predict
869Phosphothreonine(CK2)HMM predict
932Phosphoserine(ATM)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_001018054
  • Location:chr1 53483804-53566313
  • strand:-
No data
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 53516553 53516789 236 0
CTCF CD4SISSRdata 53516553 53516789 236 0
CTCF JurkatGSE12889 53516505 53516799 294 0
CTCF G2GSE9613 53487755 53487930 175 0
CTCF G2GSE9613 53493226 53493474 248 0
CTCF G2GSE9613 53504372 53504804 432 0
CTCF G2GSE9613 53514977 53515388 411 0
CTCF G2GSE9613 53515990 53516985 995 0
CTCF G2GSE9613 53525861 53526344 483 0
CTCF G2GSE9613 53531373 53531582 209 0
CTCF G2GSE9613 53532243 53532607 364 0
CTCF G2GSE9613 53545474 53545932 458 0
CTCF G2GSE9613 53549361 53550239 878 0
CTCF G2GSE9613 53554174 53554351 177 0
CTCF G2GSE9613 53554946 53555681 735 0
CTCF G2GSE9613 53560633 53561186 553 0
CTCF G2GSE9613 53563928 53566070 2142 0
Fos K562GSE19551 53564048 53565085 1037 0
H3K4me3 colorectalcancer 53565833 53566070 237 0
H3ac HepG2E 53563710 53564115 405 0
H3ac HepG2E 53565344 53565665 321 0
NFkBII GM12878GSE19485 53530081 53531803 1722 0
Oct1 H2O2-HelaGSE14283 53493429 53493456 27 0
PHF8 Hs68plusFBSGSE20725 53563764 53565524 1760 0
SRF GMOGSE8489 53508211 53508384 173 0
SRF HepG2GSE8489 53508104 53508384 280 0
USF1 HepG2E 53563710 53564340 630 0
hScc1 BcellGSE12603 53504419 53505034 615 0
hScc1 BcellGSE12603 53512351 53512705 354 0
hScc1 BcellGSE12603 53513996 53514375 379 0
hScc1 BcellGSE12603 53514977 53515334 357 0
hScc1 BcellGSE12603 53515812 53515990 178 0
hScc1 BcellGSE12603 53516554 53516985 431 0
hScc1 BcellGSE12603 53522543 53522903 360 0
hScc1 BcellGSE12603 53525414 53525547 133 0
hScc1 BcellGSE12603 53542993 53543667 674 0
hScc1 BcellGSE12603 53548788 53550239 1451 0
hScc1 BcellGSE12603 53562909 53563077 168 0
hScc1 BcellGSE12603 53563847 53566070 2223 0
hScc1 CdLSGSE12603 53516492 53516985 493 0
Validated miRNA targets Top
Cis-Nats regulation Top
Cluster ID Plue Type Plus Gene Name Plus Chromosome Plus Start Plus End Overlap Length Minus Type Minus Gene Name Minus Chromosome Minus Star Minus End Type
803 EST chr1 53465716 53467399 123 mRNA LRP8 chr1 53423238 53505747Sense/Antisense (SA) pairs

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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