AutismKB 2.0

Annotation Detail for PXDN


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Basic Information Top
Gene Symbol:PXDN ( D2S448,D2S448E,KIAA0230,MG50,PRG2,PXN,VPO )
Gene Full Name: peroxidasin homolog (Drosophila)
Band: 2p25.3
Quick LinksEntrez ID:7837; OMIM: 605158; Uniprot ID:PXDN_HUMAN; ENSEMBL ID: ENSG00000130508; HGNC ID: 14966
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
640N-linked (GlcNAc...) (Potential).
699N-linked (GlcNAc...) (Potential).
719N-linked (GlcNAc...) (Potential).
731N-linked (GlcNAc...) (Potential).
865N-linked (GlcNAc...) (Potential).
1176Phosphotyrosine.
1178N-linked (GlcNAc...).
1180Phosphoserine.
1280N-linked (GlcNAc...) (Potential).
1368N-linked (GlcNAc...) (Potential).
1425N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
No data
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_012293
  • Location:chr2 1614666-1727297
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF CD4GSE12889 1733696 1733894 198 6498
CTCF CD4SISSRdata 1733696 1733894 198 6498
CTCF G2GSE9613 1730124 1730751 627 3140
CTCF G2GSE9613 1732101 1732352 251 4929
CTCF G2GSE9613 1733544 1734503 959 6726
H3K27me3 colorectalcancer 1728686 1730235 1549 2163
PHF8 HeLaGSE20725 1726715 1727982 1267 51
PHF8 Hs68minusFBSGSE20725 1726775 1727914 1139 47
Rb SenescentGSE19898 1738704 1738920 216 11515
hScc1 BcellGSE12603 1733544 1734289 745 6619
hScc1 BcellGSE12603 1741688 1741818 130 14456
hScc1 G2GSE9613 1733544 1734503 959 6726
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 1600239 1601144 905 13975
FOXA1 MCF7GSE15244 1604598 1605179 581 9778
FOXA1 MCF7GSE15244 1608017 1608696 679 6310
FoxA1 MCF7MACSdata 1600535 1600675 140 14062
FoxA1 MCF7MACSdata 1608136 1608325 189 6436
KLF4 hESGSE17917 1600947 1601108 161 13639
KLF4 hESGSE17917 1607992 1608428 436 6457
Nanog hESGSE18292 1597075 1597662 587 17298
Oct4 hESGSE17917 1608178 1608511 333 6322
Stat6 IL-4-hr4GSE17850 1605607 1606196 589 8765
TFAP2C MCF7GSE21234 1600192 1601049 857 14046
TFAP2C MCF7GSE21234 1607797 1608783 986 6377
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CBP T30-glioblastomaGSE21026 1703675 1705247 1572 0
CTCF G2GSE9613 1617725 1618015 290 0
CTCF G2GSE9613 1619872 1620758 886 0
CTCF G2GSE9613 1622491 1623123 632 0
CTCF G2GSE9613 1623366 1623891 525 0
CTCF G2GSE9613 1625138 1625457 319 0
CTCF G2GSE9613 1630660 1630964 304 0
CTCF G2GSE9613 1633934 1634666 732 0
CTCF G2GSE9613 1639772 1640450 678 0
CTCF G2GSE9613 1640716 1641800 1084 0
CTCF G2GSE9613 1646520 1646888 368 0
CTCF G2GSE9613 1657816 1658573 757 0
CTCF G2GSE9613 1658864 1659126 262 0
CTCF G2GSE9613 1660305 1660921 616 0
CTCF G2GSE9613 1664317 1664682 365 0
CTCF G2GSE9613 1668778 1668943 165 0
CTCF G2GSE9613 1677979 1678782 803 0
CTCF G2GSE9613 1686622 1686898 276 0
CTCF G2GSE9613 1691846 1692428 582 0
CTCF G2GSE9613 1697156 1697630 474 0
CTCF G2GSE9613 1701446 1702460 1014 0
CTCF G2GSE9613 1711659 1711812 153 0
CTCF G2GSE9613 1714171 1714313 142 0
CTCF G2GSE9613 1719844 1719987 143 0
CTCF G2GSE9613 1723727 1724089 362 0
CTCF G2GSE9613 1726273 1727884 1611 0
ER Breast-CancerGSE22609 1675171 1675900 729 0
ER Breast-CancerGSE22609 1705220 1706068 848 0
ER MCF7GSE19013 1675063 1675905 842 0
ER MCF7GSE19013 1687986 1688776 790 0
FOXA1 MCF7GSE15244 1614441 1615139 698 0
FOXA1 MCF7GSE15244 1685827 1687384 1557 0
FOXA1 MCF7GSE15244 1690500 1691202 702 0
FoxA1 MCF7MACSdata 1614629 1614947 318 0
H3K27me3 colorectalcancer 1724863 1725362 499 0
HIF1 HypoHepG2 1685827 1687384 1557 0
Nanog hESGSE18292 1690623 1691206 583 0
Nanog hESGSE18292 1713402 1713821 419 0
Oct4 hESGSE17917 1683264 1683483 219 0
P300 T0-glioblastomaGSE21026 1703750 1704445 695 0
P300 T30-glioblastomaGSE21026 1614362 1615303 941 0
P300 T30-glioblastomaGSE21026 1712677 1715440 2763 0
SRF HelaGSE8489 1638985 1639323 338 0
Sox2 hESGSE18292 1691012 1691176 164 0
TFAP2C MCF7GSE21234 1614551 1615639 1088 0
TFAP2C MCF7GSE21234 1616739 1617728 989 0
TFAP2C MCF7GSE21234 1690422 1691124 702 0
TFAP2C MCF7GSE21234 1699812 1700366 554 0
TFAP2C MCF7GSE21234 1725663 1726174 511 0
hScc1 BcellGSE12603 1619837 1620688 851 0
hScc1 BcellGSE12603 1623614 1623891 277 0
hScc1 BcellGSE12603 1631436 1632235 799 0
hScc1 BcellGSE12603 1663274 1663846 572 0
hScc1 BcellGSE12603 1667922 1668320 398 0
hScc1 BcellGSE12603 1701446 1701918 472 0
hScc1 BcellGSE12603 1726157 1726753 596 0
hScc1 G2GSE9613 1678013 1678782 769 0
hScc1 G2GSE9613 1726318 1727884 1566 0
p130 shRbQuiescentGSE19898 1636072 1636729 657 0
p63 keratinocytesGSE17611 1687444 1688295 851 0
Validated miRNA targets Top
Micro RNA Name Stem Loop Name The chromosome that miRNA located Publication
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-let-7b* hsa-let-7b 22 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-1 hsa-mir-1-2 18 18668040
hsa-miR-1 hsa-mir-1-1 20 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155 hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-155* hsa-mir-155 21 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-16 hsa-mir-16-1 13 18668040
hsa-miR-16 hsa-mir-16-2 3 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30a* hsa-mir-30a 6 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30b* hsa-mir-30b 8 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c hsa-mir-30c-2 6 18668040
hsa-miR-30c hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-1* hsa-mir-30c-1 1 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30c-2* hsa-mir-30c-2 6 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30d* hsa-mir-30d 8 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
hsa-miR-30e* hsa-mir-30e 1 18668040
ID in Tarbase Data Type Support Type miRNA Gene Direct Support Publication
886 Unknown pSILAC let-7b PXDN down 50-25% 18668040
Ensembl Protein Type Differentially expressed in Pathology or Event Mis Regulation Gene Expression Tumour Involvement
ENSG00000130508 n_a n_a n_a "epithelium, squamous cell, lymphocyte, muscle cell" "benign tumour, malignant tumour, carcinoma, sarcoma"
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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