AutismKB 2.0

Annotation Detail for IL1R2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IL1R2 ( CD121b,IL1RB,MGC47725 )
Gene Full Name: interleukin 1 receptor, type II
Band: 2q11.2
Quick LinksEntrez ID:7850; OMIM: 147811; Uniprot ID:IL1R2_HUMAN; ENSEMBL ID: ENSG00000115590; HGNC ID: 5994
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
22Phosphothreonine (By similarity).
66N-linked (GlcNAc...) (Potential).
72N-linked (GlcNAc...) (Potential).
109Phosphothreonine (By similarity).
112N-linked (GlcNAc...).
219N-linked (GlcNAc...).
277N-linked (GlcNAc...) (Potential).
Location(AA) Modifications Resource
66N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
72N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
112N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
219N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
277N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
Location(AA) Modification Resource
66N-linkedHMM predict
72N-linkedHMM predict
106Phosphotyrosine(Jak)HMM predict
106Phosphotyrosine(INSR)HMM predict
109O-linkedHMM predict
112N-linkedHMM predict
114Phosphoserine(PKB)HMM predict
143O-linkedHMM predict
218Phosphotyrosine(Abl)HMM predict
219N-linkedHMM predict
241Phosphoserine(CDK)HMM predict
241Phosphoserine(CDC2)HMM predict
255Phosphothreonine(PKC)HMM predict
277N-linkedHMM predict
299PhosphoserineHMM predict
305Phosphotyrosine(EGFR)HMM predict
377Phosphothreonine(PKA)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_004633
  • Location:chr2 101974737-102011311
  • strand:+
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101961824 101963351 1527 12150
CTCF G2GSE9613 101965749 101966061 312 8833
CTCF G2GSE9613 101969297 101969577 280 5301
NFkBII GM12878GSE19485 101959182 101960724 1542 14785
Oct1 H2O2-HelaGSE14283 101968871 101968899 28 5853
Oct1 HelaGSE14283 101971915 101971956 41 2802
No data
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 101980169 101980529 360 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018