AutismKB 2.0

Annotation Detail for SCG2


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Basic Information Top
Gene Symbol:SCG2 ( CHGC,SN,SgII )
Gene Full Name: secretogranin II
Band: 2q36.1
Quick LinksEntrez ID:7857; OMIM: 118930; Uniprot ID:SCG2_HUMAN; ENSEMBL ID: ENSG00000171951; HGNC ID: 10575
Relate to Another Database: SFARIGene; denovo-db
Post Translation Modification Top
Location(AA) Modification
151Sulfotyrosine.
532Phosphoserine.
533Phosphoserine.
Location(AA) Modifications Resource
151Sulfotyrosine.Swiss-Prot 53.0
532Phosphoserine.Swiss-Prot 53.0
533Phosphoserine.Swiss-Prot 53.0
Location(AA) Modification Resource
74Phosphoserine(CK2)HMM predict
74Phosphoserine(CK1)HMM predict
78Phosphotyrosine(Syk)HMM predict
78SulfotyrosineHMM predict
81Phosphotyrosine(Syk)HMM predict
104Phosphoserine(CK1)HMM predict
106Phosphoserine(CK1)HMM predict
151SulfotyrosineHMM predict
151Phosphotyrosine(Syk)HMM predict
226SulfotyrosineHMM predict
227Phosphothreonine(CK2)HMM predict
268Phosphoserine(CK1)HMM predict
285Phosphoserine(PKG)HMM predict
299Phosphoserine(PKG)HMM predict
376N-linkedHMM predict
415Phosphotyrosine(EGFR)HMM predict
418Phosphothreonine(MAPK)HMM predict
418Phosphothreonine(CDC2)HMM predict
457Phosphotyrosine(Abl)HMM predict
556Phosphoserine(ATM)HMM predict
579Phosphothreonine(CDK)HMM predict
579Phosphothreonine(MAPK)HMM predict
579Phosphothreonine(CDC2)HMM predict
Validated transcription factor binding site by ChIP-Chip and ChIP-Seq
  • RefSeq ID: NM_003469
  • Location:chr2 224169903-224175364
  • strand:-
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF JurkatGSE13047 224175000 224175836 836 54
NRSF JurkatSISSRdata 224175046 224175765 719 41
NRSF-mono JurkatQuESTdata 224174999 224175818 819 44
NRSF-poly JurkatQuESTdata 224175038 224175777 739 43
Nanog hESGSE18292 224191224 224191767 543 16131
P300 T30-glioblastomaGSE21026 224185551 224187009 1458 10916
Sox2 hESGSE18292 224191111 224191780 669 16081
TFAP2C MCF7GSE21234 224185945 224186645 700 10931
p130 shRbSenescentGSE19898 224186090 224186509 419 10935
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
CTCF G2GSE9613 224165947 224166149 202 3856
Nanog hESGSE18292 224161105 224161625 520 8539
P300 T30-glioblastomaGSE21026 224149655 224150503 848 19825
Transcrip Factors Experimental Cell Database TF Binding Start TF Binding End TF Binding Length The Distance to Gene
NRSF mAbJurkat 224170288 224172046 1758 0
NRSF mAbJurkat 224172477 224177763 5286 0
NRSF-mono JurkatQuESTdata 224174740 224174984 244 0
hScc1 G2GSE9613 224175112 224175546 434 0
Validated miRNA targets Top
Cis-Nats regulation Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018